Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Toshihide Nishishita"'
Autor:
Shinji Shimada, Yutaka Kawakami, Takashi Nakaoka, Hiroyuki Fukuda, Kenta Yoshiura, Naohide Yamashita, Toshihide Nishishita, Toshiaki Saida, Akifumi Yamamoto, Shinobu Imajoh-Ohmi, Tsuneo A. Takahashi, Katsuaki Sato, Naoki Oyaizu
Publikováno v:
Clinical Cancer Research. 11:8201-8207
Tumor-associated antigens are promising candidates as target molecules for immunotherapy and a wide variety of tumor-associated antigens have been discovered through the presence of serum antibodies in cancer patients. We previously conducted dendrit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7a6921859d7df6f85bd3c57490e8255
https://doi.org/10.1158/1078-0432.ccr-05-0816
https://doi.org/10.1158/1078-0432.ccr-05-0816
Autor:
Koichiro Kuwabara, Kenta Yoshiura, Kunie Ouchi, Xiaohong Zhang, Takashi Nakaoka, Mariko Inoue, Toshihide Nishishita, Naohide Yamashita, Tsuneo A. Takahashi, Nobukazu Watanabe, Koichi Igura, Takeshi Inazawa
Publikováno v:
Biochemical and Biophysical Research Communications. 325:24-31
Recently several strategies to treat ischemic diseases have been proposed but the ideal way has to be determined. We explored whether human placenta-derived mesenchymal cells (hPDMCs) can be used for this purpose because placenta is very rich in vess
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2910b7ecbc018338cb592cccda22a92c
https://doi.org/10.1016/j.bbrc.2004.10.003
https://doi.org/10.1016/j.bbrc.2004.10.003
Autor:
Takashi Nakaoka, Toshihide Nishishita, Naohide Yamashita, Koichiro Kuwabara, Terukatsu Sasaki, Kaori Sato
Publikováno v:
Endocrinology. 145:3324-3330
Proline-rich tyrosine kinase 2 (Pyk2), a member of the focal adhesion kinase family, is thought to act as a key component in vasculogenesis and angiogenesis. Therefore, we studied the effect of mutant Pyk2 expression on the migration and proliferatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3dabb60d6cf713e8ad88854231e461a
https://doi.org/10.1210/en.2003-1433
https://doi.org/10.1210/en.2003-1433
Autor:
Pengnain Charles Lin, Ying Chen, James W. Thomas, Laura M. DeBusk, Jin Chen, Toshihide Nishishita
Publikováno v:
Arthritis & Rheumatism. 48:2461-2471
Objective Rheumatoid arthritis (RA) is an inflammatory disease and an angiogenic disease. However, the molecular mechanisms promoting angiogenesis in RA are not clearly identified. Our objective was to study the role of an endothelium-specific recept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9088b012cd7a689977ab3a0f7cca5c2
https://doi.org/10.1002/art.11213
https://doi.org/10.1002/art.11213
Publikováno v:
Journal of Biological Chemistry. 275:13420-13426
Recent studies of beta(2)-adrenergic receptor suggest that agonist-promoted receptor internalization may play an important role in extracellular signal-regulated kinase (ERK) activation by G protein-coupled receptors. In the present study, we explore
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::244df9d045bd00316237980bcd095d87
https://doi.org/10.1074/jbc.275.18.13420
https://doi.org/10.1074/jbc.275.18.13420
Autor:
Ung-il Chung, Shogo Ebisu, Toshiro Fujita, Akira Suwa, Hiroko Iwanari, Toshihide Nishishita, Etsuro Ogata, Tetsuya Igarashi, Keishi Hata, Tomoki Okazaki, Akihiro Iwamatsu, Tsuneyo Mimori
Publikováno v:
Journal of Biological Chemistry. 271:8593-8598
Through the specific binding of a negative calcium-responsive element to its binding protein in response to extracellular Ca (Ca2+e), negative calcium-responsive element-bearing genes, such as the human parathyroid hormone gene, are negatively regula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11cad5c7304a23f5e168ab06e2d555b9
https://doi.org/10.1074/jbc.271.15.8593
https://doi.org/10.1074/jbc.271.15.8593
Autor:
Tetsuya Igarashi, Etsuro Ogata, Ung-il Chung, S Ebisu, S Usuda, S Mishiro, Taku Okazaki, S Xanthoudakis, Toshihide Nishishita
Publikováno v:
Journal of Biological Chemistry. 269:27855-27862
A rise in extracellular calcium (Ca2+e) suppresses not only secretion of parathyroid hormone (PTH) but also expression of the PTH gene to ensure constant plasma Ca2+ level. A nuclear protein(s) in a wide variety of cells bound to the specific DNA ele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51b1e949a8066159ca8bd918751d6f3f
https://doi.org/10.1016/s0021-9258(18)46865-2
https://doi.org/10.1016/s0021-9258(18)46865-2
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 28, Iss 1, p 13 (2009)
Journal of Experimental & Clinical Cancer Research : CR
Journal of Experimental & Clinical Cancer Research : CR
Background Key role of angiogenesis in tumor growth and metastasis based on accumulating evidence and recent progress of immunotherapy have led us to investigate vaccine therapy targeting tumor angiogenesis. Methods C57BL/6J mice were vaccinated with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4016a4bb744979a5782a428866b6dec
https://doi.org/10.1186/1756-9966-28-13
https://doi.org/10.1186/1756-9966-28-13
Publikováno v:
Journal of molecular endocrinology. 39(6)
The mitogen-activated protein kinases (MAPKs) signaling pathway is a potential target in cancer therapy. Constitutive phosphorylated extracellular signal-regulated kinase (ERK1/2), which is one of the MAPKs has been detected in a variety of tumors. C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::427bf785fb2dd389a42672f1e1fbb1b4
https://pubmed.ncbi.nlm.nih.gov/18055485
https://pubmed.ncbi.nlm.nih.gov/18055485
Autor:
Xiaohong Zhang, Tsuneo A. Takahashi, Naohide Yamashita, Takashi Nakaoka, Kenichi Shinomiya, Nobukazu Watanabe, Koichi Igura, Toshihide Nishishita
Publikováno v:
Microbiology and immunology. 47(1)
Mesenchymal cells from various sources are pluripotent and are attractive sources for cell transplantation. In this study, we analyzed recombinant adeno-associated virus (rAAV)-mediated gene expression in human placenta-derived mesenchymal cells (hPD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac1ad26a5e59ea4410ac9d86f3438248
https://pubmed.ncbi.nlm.nih.gov/12636261
https://pubmed.ncbi.nlm.nih.gov/12636261