Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Toshiharu Akiyama"'
Autor:
Tomonari Suda, Hiroaki Kobayashi, Toshiharu Akiyama, Takuya Takano, Misa Gokyu, Takeaki Sudo, Thatawee Khemwong, Yuichi Izumi
Publikováno v:
Journal of Clinical and Diagnostic Research, Vol 9, Iss 9, Pp ZC46-ZC49 (2015)
Background: Dentin hypersensitivity can interfere with optimal periodontal care by dentists and patients. The pain associated with dentin hypersensitivity during ultrasonic scaling is intolerable for patient and interferes with the procedure, part
Externí odkaz:
https://doaj.org/article/4d77d8ebe68b435f8eb34f35f23198c4
Autor:
Takuya Takano, Tomonari Suda, Misa Gokyu, Toshiharu Akiyama, Takeaki Sudo, Thatawee Khemwong, Hiroaki Kobayashi, Yuichi Izumi
Publikováno v:
Journal of Clinical and Diagnostic Research, Vol 9, Iss 9, Pp ZC46-ZC49 (2015)
Background Dentin hypersensitivity can interfere with optimal periodontal care by dentists and patients. The pain associated with dentin hypersensitivity during ultrasonic scaling is intolerable for patient and interferes with the procedure, particul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b635e0c8d9b00a798d8cdfa2dce1f60
https://doi.org/10.7860/jcdr/2015/13775.6495
https://doi.org/10.7860/jcdr/2015/13775.6495
Autor:
Munenori Otani, Ken-Ichiro Fukumitsu, Makoto Otsuki, Dongmei Jia, Hiroyuki Yoshikawa, Mitsuyoshi Yamamoto, Toshiharu Akiyama
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 285:G681-G687
Recent studies demonstrated that cholecystokinin (CCK) at physiological levels stimulates pancreatic enzyme secretion via a capsaicin-sensitive afferent vagal pathway. This study examined whether chemical ablation of afferent vagal fibers influences
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00108e1f0561fc781d8c549c555cd1c7
https://doi.org/10.1152/ajpgi.00312.2002
https://doi.org/10.1152/ajpgi.00312.2002
Publikováno v:
Pancreas. 25:57-62
Introduction Dibutyltin dichloride (DBTC) is widely used as a stabilizer for polyvinylchloride plastics and is of particular toxicologic interest. Aim To examine the effects of DBTC on pancreatic exocrine function in isolated rat pancreatic acini. Me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9499507fb29a81593179f36688055d6f
https://doi.org/10.1097/00006676-200207000-00014
https://doi.org/10.1097/00006676-200207000-00014
Autor:
Toshiharu Akiyama, Mitsuo Tashiro, Yoshinori Okabayashi, Issei Imoto, Yoshihide Hirohata, Makoto Otsuki, Masatoshi Fujii, Yoshikuni Nagashio
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 282:G249-G256
Considered to be an etiologic factor of acute pancreatitis, hypersecretion of pancreatic juice and digestive enzymes is often associated with hyperbilirubinemia. We explored the intracellular mechanisms through which bilirubin affects pancreatic exoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e56851a78634651c36bcf7f98a519b0b
https://doi.org/10.1152/ajpgi.00429.2000
https://doi.org/10.1152/ajpgi.00429.2000
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 280:R1332-R1340
We examined the effect of troglitazone treatment on pancreatic growth in the CCK-A receptor-deficient Otsuka Long-Evans Tokushima fatty (OLETF) rat, an animal model for type 2 diabetes mellitus. A troglitazone-rich diet (0.2%) was given from 12 to 28
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2e15ac1b601c430454f1ca5578e93c8
https://doi.org/10.1152/ajpregu.2001.280.5.r1332
https://doi.org/10.1152/ajpregu.2001.280.5.r1332
Autor:
Akinari Tabaru, Toshiharu Akiyama, Makoto Otsuki, Ken-Ichiro Fukumitsu, Dong Mei Jia, Hayato Nakamura
Publikováno v:
Metabolism. 49:1167-1175
Troglitazone has been shown to improve insulin sensitivity and thereby exert hypoglycemic effects in various animal models and humans with insulin resistance and diabetes. The recently established animal model of naturally occurring obese diabetes, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a08e3e3f9ebf84dda6cfa5eeca5116ac
https://doi.org/10.1053/meta.2000.8599
https://doi.org/10.1053/meta.2000.8599
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 275:G1202-G1208
Exocrine pancreatic secretion stimulated by vasoactive intestinal polypeptide (VIP), which acts through the adenylyl cyclase-cAMP pathway, is potentiated by stimulation with other secretagogues such as CCK and carbachol (CCh). However, the potentiati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c0b30f729a394f5306c0d3813b290a0
https://doi.org/10.1152/ajpgi.1998.275.5.g1202
https://doi.org/10.1152/ajpgi.1998.275.5.g1202
Publikováno v:
Biochemical Pharmacology. 55:677-685
The effects of vanadate on exocrine pancreatic function were examined in isolated rat pancreatic acini. Vanadate caused a concentration-dependent stimulation of amylase release above a concentration of 1 mM. Co-incubation of vanadate with vasoactive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b5fc2171315acd632e12d94c0249448
https://doi.org/10.1016/s0006-2952(97)00543-1
https://doi.org/10.1016/s0006-2952(97)00543-1
Publikováno v:
Diabetes Research and Clinical Practice. 31:27-35
There is strong evidence that genetic factors contribute to the development of obesity in humans as well as laboratory animals. Another important factor leading to obesity is an increase in energy intake. However, it is difficult to make normal rats
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::724c7bedfa3b067caa038e11d424e161
https://doi.org/10.1016/0168-8227(96)01205-3
https://doi.org/10.1016/0168-8227(96)01205-3