Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Toshifumi Tomoda"'
Autor:
Hiroaki Mochizuki, Hirofumi Toda, Mai Ando, Mitsuhiko Kurusu, Toshifumi Tomoda, Katsuo Furukubo-Tokunaga
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e19632 (2011)
Members of the evolutionary conserved Ser/Thr kinase Unc-51 family are key regulatory proteins that control neural development in both vertebrates and invertebrates. Previous studies have suggested diverse functions for the Unc-51 protein, including
Externí odkaz:
https://doaj.org/article/347ac684a24843a08ec95b0aec17f69d
Publikováno v:
Journal of Visualized Experiments.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cfaa93d036ace1c430ee50e75e697ee5
https://doi.org/10.3791/65063
https://doi.org/10.3791/65063
Autor:
Xiaolu Zhang, Mahmoud Ali Eladawi, William George Ryan, Xiaoming Fan, Stephen Prevoznik, Trupti Devale, Barkha Ramnani, Krishnamurthy Malathi, Etienne Sibille, Robert Mccullumsmith, Toshifumi Tomoda, Rammohan Shukla
The underlying biological mechanisms that contribute to the heterogeneity of major depressive disorder (MDD) presentation remain poorly understood, highlighting the need for a conceptual framework that can explain this variability and bridge the gap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c08b5ff1661c7d9496f65b24c5ea1d6
https://doi.org/10.1101/2023.05.04.539419
https://doi.org/10.1101/2023.05.04.539419
Autor:
Hanna Jaaro-Peled, Sunil Kumar, Dalton Hughes, Akiko Sumitomo, Sun-Hong Kim, Sandra Zoubovsky, Yuki Hirota-Tsuyada, Diana Zala, Julie Bruyere, Brittany M. Katz, Beverly Huang, Rafael Flores, Soumya Narayan, Zhipeng Hou, Aris N. Economides, Takatoshi Hikida, William C. Wetsel, Karl Deisseroth, Susumu Mori, Nicholas J. Brandon, Motomasa Tanaka, Koko Ishizuka, Miles D. Houslay, Frédéric Saudou, Kafui Dzirasa, Akira Sawa, Toshifumi Tomoda
Publikováno v:
Molecular Psychiatry. 27:1805-1815
Sensorimotor information processing underlies normal cognitive and behavioral traits and has classically been evaluated through prepulse inhibition (PPI) of a startle reflex. PPI is a behavioral dimension deregulated in several neurological and psych
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52c5361c7dcda2626d9b38677ea2d8ef
https://doi.org/10.1038/s41380-021-01389-3
https://doi.org/10.1038/s41380-021-01389-3
Autor:
Akiko Sumitomo, Habil Zare, David A. Lewis, Etienne Sibille, Robert E. McCullumsmith, Dwight F. Newton, Toshifumi Tomoda, Rammohan Shukla
Publikováno v:
Molecular Psychiatry. 27:1083-1094
Major depressive disorder (MDD) is a brain disorder often characterized by recurrent episode and remission phases. The molecular correlates of MDD have been investigated in case-control comparisons, but the biological alterations associated with illn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72d7340bd2e0f8099ba0afd25e2ea163
https://doi.org/10.1038/s41380-021-01347-z
https://doi.org/10.1038/s41380-021-01347-z
Autor:
Akiko Sumitomo, Toshifumi Tomoda
Publikováno v:
Current Opinion in Pharmacology. 60:133-140
Neural circuit functions critically depend on homeostatic regulation and quality control of neuronal proteins and organelles. Emerging evidence shows that autophagy, cellular clearance machinery, selectively degrades or controls homeostasis of both p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22ea9c28c9b40f9ee536276608bc764f
https://doi.org/10.1016/j.coph.2021.07.013
https://doi.org/10.1016/j.coph.2021.07.013
Autor:
Kun Yang, Koko Ishizuka, Andrew P. Lane, Zui Narita, Yukiko Y. Lema, Toshifumi Tomoda, Atsushi Kamiya, Minghong Ma, Donald Geman, Laurent Younes, Akira Sawa
Biopsy is crucial in clinical medicine to obtain tissues and cells that may directly reflect the pathological changes of each disease. However, the brain is an exception due to ethical and practical challenges. Nasal biopsy, which captures olfactory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f92b47b51b764167a6f7e359037f3cc
https://doi.org/10.1101/2022.09.23.509290
https://doi.org/10.1101/2022.09.23.509290
Autor:
Etienne Sibille, James Minton Cook, Mounira Banasr, Guanguan Li, Toshifumi Tomoda, Thomas Prevot, Daniel E Knutson, Sepideh Rezvanian, Dishary Sharmin, Kamal Prasad Pandey, Yeunus Mian, PRITHU MONDAL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06cdc74833d82c488e6d4ca19ff9d3c7
https://doi.org/10.1021/scimeetings.2c00466
https://doi.org/10.1021/scimeetings.2c00466
Publikováno v:
Biol Psychiatry
Homeostatic maintenance of physiological functions is fundamental to organismal well-being. Disruption or imbalance in homeostasis results in functional disturbances at molecular, cellular, and tissue levels, leading to manifestation as physical and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab07d9c0f3642e56a3c71b1f412d8924
https://doi.org/10.1016/j.biopsych.2019.07.018
https://doi.org/10.1016/j.biopsych.2019.07.018
Autor:
Takuya Sakamoto, Hiroko Shimbo, Seiji Shioda, Tomoya Nakamachi, Yasumasa Nishito, Hideki Miwa, Junjiro Horiuchi, Toshio Miyata, Yasuto Kunii, Atsuko Nagaoka, Toshifumi Tomoda, Mitsuhiro Miyashita, Takatoshi Hikida, Hirooki Yabe, Haruo Okado, Takashi Dan, Ryuta Izumi, Makoto Arai, Masanari Itokawa, Kazuhiro Suzuki, Mizuki Hino, Kazuya Toriumi, Tomoko Tanaka, Shinobu Hirai
Publikováno v:
Science Advances
Description
High-sugar diet in adolescence induces neural angiopathy and multiple psychiatric endophenotypes with impaired glucose logistics.
Metabolic dysfunction is thought to contribute to the severity of psychiatric disorders; however,
High-sugar diet in adolescence induces neural angiopathy and multiple psychiatric endophenotypes with impaired glucose logistics.
Metabolic dysfunction is thought to contribute to the severity of psychiatric disorders; however,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2b2e4588dd7f8d2f09ac1bb3c9e440a
http://europepmc.org/articles/PMC8580307
http://europepmc.org/articles/PMC8580307