Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Toshie Kanayasu-Toyoda"'
Autor:
Toshie Kanayasu-Toyoda, Eriko Uchida, Akifumi Matsuyama, Hiroko Kitagawa, Teruhide Yamaguchi, Takeshi Tanaka, Akiko Ishii-Watabe
Publikováno v:
Journal of Cellular Physiology. 230:2763-2775
Since the introduction of angiogenic cell therapy using early endothelial progenitor cells (EPCs), myeloid angiogenic cells (MACs) have been expected to be useful in treating ischemic diseases. In order to elucidate the angiogenic properties of MACs/
Autor:
Takuo Suzuki, Hiroko Kitagawa, Hiroyuki Mizuguchi, Yutaka Kikuchi, Minoru Tada, Hiroomi Tamura, Akiko Ishii-Watabe, Teruhide Yamaguchi, Hiroko Suzuki, Toshie Kanayasu-Toyoda
Publikováno v:
Journal of cellular physiology. 233(2)
Cell therapy using endothelial progenitor cells (EPCs) is a promising strategy for the treatment of ischemic diseases. Two types of EPCs have been identified: early EPCs and late EPCs. Late EPCs are able to form tube structure by themselves, and have
Publikováno v:
Biological and Pharmaceutical Bulletin. 36:176-181
Cell therapies for severe ischemic diseases such as limb ischemia, acute myocardial infarction, and cerebral ischemia have been developed through in vitro and in vivo animal and clinical studies. Active cells for angiogenic cell therapy are believed
Autor:
Masayuki Sano, Teruhide Yamaguchi, Hideyuki Sato, Hiromitsu Nakauchi, Mahito Nakanishi, Hiroaki Segawa, Yuzuru Ikehara, Yoko Umemura, Satoko Takayasu, Birei Furuta, Makoto Asashima, Ken Nishimura, Manami Ohtaka, Toshie Kanayasu-Toyoda, Kaori Motomura, Yoshiro Nakajima, Toshihiro Kobayashi, Eriko Uchida
Publikováno v:
Journal of Biological Chemistry. 286:4760-4771
The ectopic expression of transcription factors can reprogram differentiated tissue cells into induced pluripotent stem cells. However, this is a slow and inefficient process, depending on the simultaneous delivery of multiple genes encoding essentia
Autor:
Takuo Suzuki, Tetsu Kobayashi, Toshie Kanayasu-Toyoda, Teruhide Yamaguchi, Akiko Ishii-Watabe, Toru Kawanishi, Minoru Tada
Publikováno v:
The Journal of Immunology. 184:1968-1976
The neonatal FcR (FcRn) binds to the Fc domain of IgG at acidic pH in the endosome and protects IgG from degradation, thereby contributing to the long serum half-life of IgG. To date, more than 20 mAb products and 5 Fc-fusion protein products have re
Autor:
Toshie Kanayasu-Toyoda, Takayoshi Suzuki, Teruhide Yamaguchi, Akiko Ishii-Watabe, Tadashi Oshizawa
Publikováno v:
Journal of Biological Chemistry. 282:33507-33514
We previously reported that CD31(bright) cells, which were sorted from cultured AC133(+) cells of adult peripheral blood cells, differentiated more efficiently into endothelial cells than CD31(+) cells or CD31(-) cells, suggesting that CD31(bright) c
Autor:
Akifumi Matsuyama, Toshie Kanayasu-Toyoda, Teruhide Yamaguchi, Yutaka Kikuchi, Takeshi Tanaka, Eriko Uchida
Publikováno v:
Stem cells (Dayton, Ohio). 34(5)
To develop cell therapies for ischemic diseases, endothelial progenitor cells (EPCs) have been expected to play a pivotal role in vascular regeneration. It is desirable to use a molecular marker that is related to the function of the cells. Here, a q
Autor:
Yoji Sato, Tadashi Oshizawa, Yasuo Ohno, Koichi Shudo, Kazuhide Inoue, Jun-ichi Sawada, Toshie Kanayasu-Toyoda, Takayoshi Suzuki, Tomoko Nishimaki-Mogami, Tomofumi Fujino, Teruhide Yamaguchi
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 94:303-309
HX531 is a retinoid X receptor (RXR) antagonist that inhibits 9-cis retinoic acid-induced neutrophilic differentiation of HL-60 cells. In order to elucidate the inhibitory mechanism of HX531, we have developed a novel ligand sensor assay for RXR in w
Autor:
Kazuhide Inoue, Mizuho Une, Koichi Shudo, Tomoko Nishimaki-Mogami, Toshie Kanayasu-Toyoda, Yoji Sato, Tomofumi Fujino, Teruhide Yamaguchi
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 87:247-252
Ligand binding to nuclear receptors leads to a conformational change that increases the affinity of the receptors to coactivator proteins. We have developed a ligand sensor assay for farnesoid X receptor (FXR) in which the receptor-coactivator intera
Publikováno v:
Biochemical Pharmacology. 66:133-140
We have previously suggested that phosphatidylinositol 3-kinase (PI3K)/p70 S6 kinase (p70 S6K) plays an important role in the regulation of neutrophilic differentiation of HL-60 cells on the basis of analysis of transferrin receptor (Trf-R)-positive