Výsledky vyhledávání - "Toshie, Sugano"

Akademický článek

In Vivo Pharmacodynamics of β-Lactams/Nacubactam against Carbapenem-Resistant and/or Carbapenemase-Producing Enterobacter cloacae and Klebsiella pneumoniae in Murine Pneumonia Model

Autor: Mao Hagihara, Hideo Kato, Toshie Sugano, Hayato Okade, Nobuo Sato, Yuichi Shibata, Daisuke Sakanashi, Jun Hirai, Nobuhiro Asai, Hiroyuki Suematsu, Yuka Yamagishi, Hiroshige Mikamo

Publikováno v: Antibiotics, Vol 10, Iss 10, p 1179 (2021)

Carbapenem-resistant Enterobacterales (CRE) and carbapenemase-producing Enterobacterales (CPE) have become global threats. CRE− and CPE− derived infections have been associated with high mortality due to limited treatment options. Nacubactam is a

Externí odkaz: https://doaj.org/article/d83c6ca51be241a785f1987f6c5e28da

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In Vivo Pharmacodynamics of β-Lactams/Nacubactam against Carbapenem-Resistant and/or Carbapenemase-Producing Enterobacter cloacae and Klebsiella pneumoniae in Murine Pneumonia Model

Autor: Toshie Sugano, Yuichi Shibata, Hideo Kato, Hiroyuki Suematsu, Mao Hagihara, Yuka Yamagishi, Nobuo Sato, Daisuke Sakanashi, Jun Hirai, Hayato Okade, Hiroshige Mikamo, Nobuhiro Asai

Publikováno v: Antibiotics
Volume 10
Issue 10
Antibiotics, Vol 10, Iss 1179, p 1179 (2021)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::763ff1e43018a128bba0c575aea608c4

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Pharmacodynamic evaluation of meropenem, cefepime, or aztreonam combined with a novel β-lactamase inhibitor, nacubactam, against carbapenem-resistant and/or carbapenemase-producing Klebsiella pneumoniae and Escherichia coli using a murine thigh-infection model

Autor: Toshie Sugano, Yuka Yamagishi, Hideo Kato, Mao Hagihara, Yusuke Koizumi, Hiroyuki Suematsu, Nobuo Sato, Hayato Okade, Hiroshige Mikamo, Daisuke Sakanashi, Yuichi Shibata, Nobuhiro Asai

Publikováno v: International journal of antimicrobial agents. 57(5)

Background Carbapenem-resistant Enterobacterales (CRE) and carbapenemase-producing Enterobacterales (CPE) are difficult to treat and are a serious public health threat. Nacubactam (NAC) is a novel non-β-lactam diazabicyclooctane β-lactamase inhibit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cc99a2f8775fc20ea3f4bc0d860ff86
https://pubmed.ncbi.nlm.nih.gov/33789129

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Investigations on yearly changes in tebipenem susceptibility of bacterial isolates from pediatric patients -A post-marketing surveillance of tebipenem pivoxil granules for pediatric

Autor: Toshie, Sugano, Toshihiko, Takata, Nami, Senju, Yoshihiro, Takayama, Takashi, Ida

Publikováno v: The Japanese journal of antibiotics. 69(4)

We conducted the post-marketing surveillance of tebipenem pivoxil (Orapeneme fine granules 10% for pediatric), an oral carbapenem antibacterial agent, to investigate changes in bacterial susceptibility against tebipenem (TBPM). Bacterial strains used

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::31cc1608b04458a2f3b874e351f68b2a
https://pubmed.ncbi.nlm.nih.gov/30226954

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Prediction of clinical bacteriological efficacy of oral antibiotics using a mechanism-based pharmacokinetic-pharmacodynamics modeling

Autor: Kayoko, Matsumoto, Toshie, Sugano, Nobuo, Sato, Takashi, Ida, Shigeki, Shibasaki

Publikováno v: The Japanese journal of antibiotics. 67(1)

The objective of this study was to predict the clinical bacteriological efficacy of antibiotics and to examine the pharmacodynamics (PD) characteristics of antibiotics against bacterial strains using a mechanism-based pharmacokinetic-pharmacodynamics

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::04b28107cecfdbb93c067994685d071e
https://pubmed.ncbi.nlm.nih.gov/24809207

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Therapeutic Effect of ME1036 on Endocarditis Experimentally Induced by Methicillin-Resistant Staphylococcus aureus

Autor: Mizuyo Kurazono, Toshie Sugano, Yoko Hirai, Sho Takahata, Jun Nagura, Minoru Yonezawa, Eiki Shitara, Keiko Yamada, Yukari Tanaka, Koji Kijima, Yoshihiro Takayama

Publikováno v: Antimicrobial Agents and Chemotherapy. 49:3526-3528

The efficacy of ME1036, a novel parenteral carbapenem, was compared with that of vancomycin by using a rabbit model of methicillin-resistant Staphylococcus aureus (MRSA) endocarditis. Compared with vancomycin, ME1036 reduced the bacterial counts in t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7157376a63291596adabab8044788bf3
https://doi.org/10.1128/aac.49.8.3526-3528.2005

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New concept and a theoretical consideration of the mechanism-based pharmacokinetics/ pharmacodynamics (PK/PD) modeling for antimicrobial agents

Autor: Nobuo, Sato, Hisashi, Suzuki, Hiroyuki, Hayashi, Shigeki, Shibasaki, Toshie, Sugano, Kazunori, Maebashi, Tohru, Kurosawa, Mari, Shiomi, Hiroyasu, Ogata

Publikováno v: The Japanese journal of antibiotics. 61(5)

Pharmacodynamic (PD) characterization (concentration-dependent, time-dependent, etc.) of antibiotics is determined by aspects of the pharmacodynamic interaction between antibiotics and microorganisms. There are three major aspects of the pharmacodyna

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1f873381b4aa486fc5cf7ff35e211fae
https://pubmed.ncbi.nlm.nih.gov/19260351

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