Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Toshiaki Suguro"'
Autor:
Takuya Watanabe, Takatoshi Koyama, Masayoshi Shichiri, Shigeaki Kimoto, Toshiaki Suguro, Kengo Sato
Publikováno v:
Regulatory Peptides. 162:129-132
Salusin-alpha was recently shown to exert anti-atherosclerotic effects and its potential role as a clinical marker for atherosclerosis has been proposed. We determined serum salusin-alpha concentrations in 99 patients across a diverse range of renal
Autor:
Toshiaki Suguro, Tetsuo Sakai, Shigeki Hongo, Takuya Watanabe, Akira Miyazaki, Shigeko Arita, Yuji Shiraishi
Publikováno v:
Current Medicinal Chemistry. 16:550-563
Human urotensin II (U-II), the most potent vasoconstrictor undecapeptide identified to date, and its receptor (UT) are involved in the pathogenesis of systemic and pulmonary hypertension. Here, we review recent advances in our understanding of the pa
Autor:
Tsunenori Idei, Nobumasa Kato, Akira Miyazaki, Yoshiyuki Ban, Ryuji Sato, Youichi Kobayashi, Tsutomu Hirano, Taka-aki Matsuyama, Yoshio Ban, Yasuko Nakano, Toshiaki Suguro, Yoshitaka Iso, Tetsuo Sakai, Hidekazu Ota, Takuya Watanabe
Publikováno v:
Journal of Atherosclerosis and Thrombosis. 16:179-187
Aim: Human urotensin-II (UII) is a cyclic neuropeptide with potent vasoconstrictive activity in the vasculature. The expression of UII and its receptor (UT) mRNA is detected at high levels in the brain. We evaluated the relationship between plasma UI
Autor:
Tsutomu Hirano, Toshiaki Suguro, Takuya Watanabe, Mitsuru Adachi, Akira Miyazaki, Gang Xu, Syuusuke Kodate
Publikováno v:
Clinical Science. 115:327-334
Human U-II (urotensin-II), the most potent vasoconstrictor peptide identified to date, is associated with cardiovascular disease. A single nucleotide polymorphism (S89N) in the gene encoding U-II (UTS2) is associated with the onset of Type 2 diabetes
Autor:
Mitsuru Adachi, Takuya Watanabe, Masaharu Nagashima, Yuji Shiraishi, Hiroyuki Itabe, Rina Kato, Shigeki Hongo, Akira Miyazaki, Tsutomu Hirano, Toshiaki Suguro
Publikováno v:
Journal of Hypertension. 26:1955-1965
Objective Our recent studies have indicated that urotensin II, the most potent vasoconstrictor peptide identified to date, potentiates human macrophage foam cell formation and vascular smooth muscle cell proliferation, and its levels are increased in
Autor:
Akira Miyazaki, Syuusuke Kodate, Masayoshi Shichiri, Tsutomu Hirano, Kengo Sato, Mitsuru Adachi, Toshiaki Suguro, Takuya Watanabe, Takatoshi Koyama, Masaharu Nagashima
Publikováno v:
Hypertension Research. 31:463-468
Salusin-alpha is a new bioactive peptide with mild hypotensive and bradycardic effects. Our recent study showed that salusin-alpha suppresses foam cell formation in human monocyte-derived macrophages by down-regulating acyl-CoA:cholesterol acyltransf
Autor:
Takuya Watanabe, Akira Miyazaki, Tomoko Kanome, Syuusuke Kodate, Mitsuru Adachi, Tsutomu Hirano, Toshiaki Suguro
Publikováno v:
Atherosclerosis. 186:275-281
Acyl-coenzyme A:cholesterol acyltransferase-1 (ACAT-1) converts intracellular free cholesterol into cholesterol ester for storage in lipid droplets and plays an important role in the formation of macrophage-derived foam cells in atherosclerotic lesio
Publikováno v:
Vascular Disease Prevention. 3:91-98
Autor:
Syuusuke Kodate, Toshiaki Suguro, Tamio Hagiwara, Akira Miyazaki, Tomoko Kanome, Shigeki Hongo, Mitsuru Adachi, Yu-Ichiro Sakamoto, Takuya Watanabe, Tsutomu Hirano
Publikováno v:
Hypertension. 46:738-744
Human urotensin II (U-II), the most potent vasoconstrictor peptide identified to date, and its receptor (UT) are involved in hypertension and atherosclerosis. Acyl-coenzyme A:cholesterol acyltransferase-1 (ACAT-1) converts intracellular free choleste
Publikováno v:
Rinsho byori. The Japanese journal of clinical pathology. 54(6)
Small dense low-density lipoprotein (sd LDL) is more atherogenic than large buoyant (lb) LDL, which is relatively high in particle number (as estimated by apolipoprotein [apo] B) and poor in cholesterol (C) content. Because recent epidemiological stu