Zobrazeno 1 - 10
of 114
pro vyhledávání: '"Toshiaki Nishihata"'
Autor:
Yusaku Matsuda, Yosuke Nonaka, Satoshi Futakawa, Hirotaka Imai, Kazumasa Akita, Toshiaki Nishihata, Masatoshi Fujiwara, Yusuf Ali, Robert B. Bhisitkul, Yoshikazu Nakamura
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 17, Iss , Pp 819-828 (2019)
Currently approved therapies for age-related macular degeneration (AMD) are inhibitors against vascular endothelial growth factor (VEGF), which is a major contributor to the pathogenesis of neovascular AMD (nAMD). Intravitreal injections of anti-VEGF
Externí odkaz:
https://doaj.org/article/80978e83ce7e4da59a94b6e8f58f10e5
Autor:
Yoshikazu Nakamura, Daniel Pereira, Raj Maturi, Kazumasa Akita, Robert Bhisitkul, Toshiaki Nishihata, Eri Sakota, Yusuf Ali, Emiko Nakamura, Padma Bezwada
Intravitreal injections of anti-vascular endothelial growth factor (VEGF) agents are the first-line treatment for exudative/wet age-related macular degeneration (wet AMD). Alternative mechanisms of action may be helpful for treatment of this very com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b111487abd297850b60e8bf4fe66e883
https://doi.org/10.21203/rs.3.rs-2656731/v1
https://doi.org/10.21203/rs.3.rs-2656731/v1
Autor:
Yoshikazu Nakamura, Toshiaki Nishihata, Satoshi Futakawa, Yusaku Matsuda, Hirotaka Imai, Masatoshi Fujiwara, Yusuf Ali, Kazumasa Akita, Robert B. Bhisitkul, Yosuke Nonaka
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 17, Iss, Pp 819-828 (2019)
Molecular Therapy. Nucleic Acids
Molecular Therapy. Nucleic Acids
Currently approved therapies for age-related macular degeneration (AMD) are inhibitors against vascular endothelial growth factor (VEGF), which is a major contributor to the pathogenesis of neovascular AMD (nAMD). Intravitreal injections of anti-VEGF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4db6f1a11c5e458a67db060efcbfc8e1
https://doi.org/10.1016/j.omtn.2019.07.018
https://doi.org/10.1016/j.omtn.2019.07.018
Autor:
Toshiaki Nishihata, J. Howard Rytting
Publikováno v:
Advanced Drug Delivery Reviews. 28:205-228
Studies of absorption-promoting adjuvants used for the modification of the barrier function of the rectal membrane are interesting for biochemical research as well as providing a basis for the development of new formulations of poorly absorbed drugs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6b8ed0406aa00e38951eea7a1712397
https://doi.org/10.1016/s0169-409x(97)00073-2
https://doi.org/10.1016/s0169-409x(97)00073-2
Publikováno v:
Drug Development and Industrial Pharmacy. 23:193-202
To characterize the progression of high-shear wet granulation for various drugs and formulations based on the particle size distribution of wet granules during granulation, a general sieving method for wet granules was investigated. Wet granulation w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::380614fd3397f91113b234faf504934c
https://doi.org/10.3109/03639049709149793
https://doi.org/10.3109/03639049709149793
Publikováno v:
International Journal of Pharmaceutics. 133:17-27
The effect of drug solubility on the dissolution from the sustained release (SR) matrix tablet prepared with hydroxypropyl methylcellulose (HPMC) 2910 4000 cps was investigated using model-independent moment analysis and Higuchi-type model analysis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::218da3ecd68f5a20ef6417d08ad0b01f
https://doi.org/10.1016/0378-5173(95)04400-0
https://doi.org/10.1016/0378-5173(95)04400-0
Publikováno v:
Drug Development and Industrial Pharmacy. 22:1041-1046
Three different tablet formulations of bropirimine were evaluated in an in vitro dissolution study. Further, the effect of dissolution rate of bropirimine and food on the bioavailability after oral administration of the tablets was investigated in do
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::edfe4a5dfa8d3d072796d1749ea441e3
https://doi.org/10.3109/03639049609065939
https://doi.org/10.3109/03639049609065939
Publikováno v:
Journal of Pharmacy and Pharmacology. 47:822-826
The postprandial effect on the bioavailability of bropirimine in dogs after oral administration of bropirimine tablets (Bropirimine 250 mg Tablet) was investigated. At a dose of 500 mg bropirimine (two tablets of bropirimine 250 mg), the maximum plas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae4bbde1cb4fd3ec7478b42726d1d90d
https://doi.org/10.1111/j.2042-7158.1995.tb05748.x
https://doi.org/10.1111/j.2042-7158.1995.tb05748.x
Publikováno v:
Journal of Controlled Release. 35:59-66
The mechanisms of sustained release (SR) from tablet matrices prepared with hydroxypropyl methylcellulose (HPMC) 2910 polymers were investigated to define the conditions for selection of appropriate polymers for SR formulation development. It is well
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ff71a79f65242db5c0164783a7a1c4c
https://doi.org/10.1016/0168-3659(95)00021-y
https://doi.org/10.1016/0168-3659(95)00021-y
Publikováno v:
Biological and Pharmaceutical Bulletin. 17:715-720
The inhibitory effect of clindamycin on beta-lactamase biosynthesis was investigated in beta-lactam resistant bacteria with inducible and/or constitutive production of the enzyme(s). Clinical isolates of Enterobacter cloacae (E. cloacae) and Pseudomo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3837de159e1c478eeb08876c8f085c7
https://doi.org/10.1248/bpb.17.715
https://doi.org/10.1248/bpb.17.715