Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Toshiaki Miyake"'
Autor:
Kazushige Sasaki, Yuzuru Akamatsu, Yohei Yamashita, Yoshihiko Kobayashi, Yoshiaki Takahashi, Takashi Kurihara, Toshiaki Miyake
Publikováno v:
The Journal of Antibiotics. 68:741-747
Arbekacin, an aminoglycoside antibiotic, is an important drug because it shows a potent efficacy against methicillin-resistant Staphylococcus aureus. However, resistance to arbekacin, which is caused mainly by the bifunctional aminoglycoside-modifyin
Autor:
Yuzuru Akamatsu, Toshiaki Miyake, Atsushi Seki, Kouji Sasaki, Yoshiaki Takahashi, Toshihiro Mori
Publikováno v:
MedChemComm. 6:581-585
The synthesis of 17-membered azalides was achieved using the following key steps: (i) Beckmann rearrangement of 16-membered oxime derivatives obtained from 3,4′-dideoxymycaminosyltylonolide (DDMT), (ii) amide-selective silane reduction of the corre
Autor:
Eijiro Umemura, Yoshihiko Kobayashi, Toru Nawa, Akihiro Morinaka, Masakatsu Shibasaki, Toshiaki Miyake, Shoichi Murakami, Yoshiaki Takahashi
Publikováno v:
The Journal of antibiotics. 71(2)
The emergence and spread of bacteria with resistance to antibacterial drugs in recent years is now considered a significant threat to global public health and the world economy.1, 2 In particular, the severe bacterial infections caused by methicillin
Publikováno v:
Tetrahedron Letters. 55:2838-2841
Methylene sp3 carbon–hydrogen bond activation of N-picolinoylcycloalkylamines provides a useful method for synthesizing cis-3-arylated cycloalkylamine derivatives. Pd(II) species catalyzed the γ-arylation of N-picolinoylcycloalkylamines with aryl
Publikováno v:
The Journal of Antibiotics. 68:421-423
Synthesis and antibacterial activity of 1- N -[( S )-ω-amino-2-hydroxyalkyl] derivatives of dibekacin, 5-deoxydibekacin, 3′-deoxykanamycin A and gentamicin B
Autor:
Masayuki Igarashi, Seiko Hattori, Yoshiaki Takahashi, Norio Doi, Yuzuru Akamatsu, Naoko Nakagawa, Yoshiko Koyama, Toshiaki Miyake, Kanae Ishikawa, Kunio Inoue, Yasuhiro Komatsuki, Hiromi Soutome
Publikováno v:
The Journal of Antibiotics. 66:171-178
Acidic treatment of a mixture of caprazamycins (CPZs) A-G isolated from a screen of novel antimycobacterial agents gave caprazene, a core structure of CPZs, in high yield. Chemical modification of the resulting caprazene was performed to give its var
Autor:
Yasujiro Taguchi, Kenichi Kato, Yoshihiro Iwasa, Toshiaki Miyake, Serena Margadonna, Kosmas Prassides
Publikováno v:
Journal of the American Chemical Society. 128:3313-3323
We report on the first synthesis of Li-intercalated manganese-phthalocyanine (MnPc) in the bulk form and on the evolution of the structural and magnetic properties as a function of Li concentration, x. We find that solid beta-MnPc, which comprises ro
Autor:
Hiroshi Naganawa, Masayuki Igarashi, Hikaru Nakamura, Toshiaki Miyake, Tetsuo Shitara, Yuzuru Akamatsu, Yoshiaki Takahashi
Publikováno v:
The Journal of Antibiotics. 58:327-337
Novel antibiotics, active against acid-fast bacteria, caprazamycins, were isolated from the culture broth of Streptomyces sp. MK730-62F2. The planar structures of the compounds were determined by 2D NMR spectroscopic study. Furthermore, the absolute
Publikováno v:
ChemInform. 45
Methylene sp3 carbon–hydrogen bond activation of N-picolinoylcycloalkylamines provides a useful method for synthesizing cis-3-arylated cycloalkylamine derivatives. Pd(II) species catalyzed the γ-arylation of N-picolinoylcycloalkylamines with aryl
Publikováno v:
Plant production science. 4(4):304-310
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論文(Article)