Zobrazeno 1 - 10
of 152
pro vyhledávání: '"Toshiaki Kubota"'
Autor:
Shunji Nakatake, Yoshiki Sato, Maho Itotani, Kenichi Kimoto, Toshiaki Kubota, Atsunobu Takeda
Publikováno v:
Case Reports in Ophthalmology, Vol 15, Iss 1, Pp 507-512 (2024)
Introduction: Perioperative visual loss (POVL) owing to hemi-retinal vein occlusion (HRVO) following prone positioning during spinal surgery is rare. Here, we report a case of HRVO with macular edema (ME) after spinal surgery that was successfully tr
Externí odkaz:
https://doaj.org/article/8044b4651e1744f8b9cb0d966f37d58e
Publikováno v:
Case Reports in Ophthalmology, Vol 13, Iss 1, Pp 9-16 (2022)
We experienced a rare case of severe peripheral ulcerative keratitis in a patient undergoing surgery combined with deep anterior lamellar keratoplasty (DALK) and peripheral lamellar keratoplasty (LK). A 63-year-old Japanese woman was referred to our
Externí odkaz:
https://doaj.org/article/bfb03cb5379546e08730c68cc3603b06
Autor:
Francesca Pasutto, Matthias Zenkel, Ursula Hoja, Daniel Berner, Steffen Uebe, Fulvia Ferrazzi, Johannes Schödel, Panah Liravi, Mineo Ozaki, Daniela Paoli, Paolo Frezzotti, Takanori Mizoguchi, Satoko Nakano, Toshiaki Kubota, Shinichi Manabe, Erika Salvi, Paolo Manunta, Daniele Cusi, Christian Gieger, Heinz-Erich Wichmann, Tin Aung, Chiea Chuen Khor, Friedrich E. Kruse, André Reis, Ursula Schlötzer-Schrehardt
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
LOXL1 is a genetic risk factor for pseudoexfoliation syndrome of the eye but a causal variant has not been identified. Here, Pasutto et al., find intronic LOXL1 risk variants influence transcription factor binding and alternative splicing of LOXL1 in
Externí odkaz:
https://doaj.org/article/4c5b624c0f3046ca8b61dfafdf853221
Publikováno v:
Case Reports in Ophthalmology, Vol 8, Iss 1, Pp 190-194 (2017)
We report a rare case with histologically proven melanocytoma of the iris that demonstrated diffuse melanocytic proliferation with uncontrolled secondary glaucoma and investigate the etiology of the intraocular pressure elevation. The patient was a 7
Externí odkaz:
https://doaj.org/article/9eb04ba12de645a9bf8550982148bbbe
Publikováno v:
Journal of Ophthalmology, Vol 2016 (2016)
Purpose. To perform multivariate analysis for identifying independent predictors of elevated intraocular pressure (IOP) with neovascular glaucoma (NVG), including antivascular endothelial growth factor (VEGF) intravitreal injections. Methods. We retr
Externí odkaz:
https://doaj.org/article/d1d5e69ff32c497796635cab2dbd2b68
Publikováno v:
Case Reports in Ophthalmology, Vol 1, Iss 1, Pp 14-19 (2010)
Aim: Infliximab, an anti-tumor necrosis factor (TNF)-α monoclonal antibody, has been reported to be effective in refractory uveoretinitis in Behçet’s disease. Because it has been used clinically for a short time, information on its adverse effect
Externí odkaz:
https://doaj.org/article/d97a29710a3a4923bb2f8b15543c3e4f
Direct Inhibition of N-Methyl-D-Aspartate (NMDA)-Receptor Function by Antiglaucomatous β-Antagonists
Autor:
Tatsuo Nagata, Susumu Ueno, Hirofumi Morita, Toshiaki Kubota, Yumiko Toyohira, Masato Tsutsui, Akihiko Tawara, Nobuyuki Yanagihara
Publikováno v:
Journal of Pharmacological Sciences, Vol 106, Iss 3, Pp 423-434 (2008)
In the present study, we investigated the direct effects of antiglaucoma drugs (timolol, betaxolol, pilocarpine, and latanoprost) on N-methyl-D-aspartate (NMDA)-receptor function using a Xenopus oocytes expression system and electrophysiological tech
Externí odkaz:
https://doaj.org/article/8b1cc9dffda24632a5921fc6e8381292
Autor:
Satoko Nakano, Emi Ikebe, Yoshiyuki Tsukamoto, Yan Wang, Takashi Matsumoto, Takahiro Mitsui, Takaaki Yahiro, Kunimitsu Inoue, Hiroaki Kawazato, Aiko Yasuda, Kanako Ito, Shigeo Yokoyama, Naohiko Takahashi, Mitsuo Hori, Tatsuo Shimada, Masatsugu Moriyama, Toshiaki Kubota, Katsushige Ono, Wataru Fujibuchi, Kuan-Teh Jeang, Hidekatsu Iha, Akira Nishizono
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e73205 (2013)
Tax1-binding protein 1 (Tax1bp1) negatively regulates NF-κB by editing the ubiquitylation of target molecules by its catalytic partner A20. Genetically engineered TAX1BP1-deficient (KO) mice develop age-dependent inflammatory constitutions in multip
Externí odkaz:
https://doaj.org/article/2db2cf33f8c34d35a7cd341ca6838de5
Publikováno v:
Journal of Ophthalmology, Vol 2012 (2012)
Externí odkaz:
https://doaj.org/article/d69800ad5ce74f26827e00cad497a2be
Autor:
Kenichi Kimoto, Toshiaki Kubota
Publikováno v:
Journal of Ophthalmology, Vol 2012 (2012)
We review articles describing intravitreal injection of anti-VEGF drug trials, while discussing the mechanisms of the action of anti-VEGF antibodies, and also evaluating their outcomes. Intraocular injections of anti-VEGF drug are considered to be an
Externí odkaz:
https://doaj.org/article/11d8212017ce46ef9bb68f8d538dec5b