Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Toshiaki Iwase"'
Autor:
Toshiaki Iwase, Kenichi Harano, Hiroko Masuda, Kumiko Kida, Kenneth R. Hess, Ying Wang, Luc Dirix, Steven J. Van Laere, Anthony Lucci, Savitri Krishnamurthy, Wendy A. Woodward, Rachel M. Layman, François Bertucci, Naoto T. Ueno
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-9 (2020)
Abstract Background The purpose of this study was to determine the prognostic role of hormone receptor (HR) on inflammatory breast cancer (IBC) to elucidate its aggressive biological behavior. Methods We evaluated the expression of estrogen receptor
Externí odkaz:
https://doaj.org/article/e7df9ce540224a8793e5c2239b2fe831
Autor:
Naoto T. Ueno, Rie K. Tahara, Takeo Fujii, James M. Reuben, Hui Gao, Babita Saigal, Anthony Lucci, Toshiaki Iwase, Nuhad K. Ibrahim, Senthil Damodaran, Yu Shen, Diane D. Liu, Gabriel N. Hortobagyi, Debu Tripathy, Bora Lim, Beth A. Chasen
Publikováno v:
Cancer Medicine, Vol 9, Iss 3, Pp 1025-1032 (2020)
Abstract Background Radium‐223 dichloride (Ra‐223) is a targeted alpha therapy that induces localized cytotoxicity in bone metastases. We evaluated the efficacy and safety of Ra‐223 plus hormonal therapy in hormone receptor‐positive (HR+), bo
Externí odkaz:
https://doaj.org/article/cad357d50e8d4880907807ce1272c30c
Autor:
Xuemei Xie, Jangsoon Lee, Jon A. Fuson, Huey Liu, Toshiaki Iwase, Kyuson Yun, Cori Margain, Debu Tripathy, Naoto T. Ueno
Publikováno v:
Biomedicines, Vol 11, Iss 3, p 735 (2023)
Background: Triple-negative breast cancer (TNBC) is the most aggressive molecular subtype of breast cancer, and current treatments are only partially effective in disease control. More effective combination approaches are needed to improve the surviv
Externí odkaz:
https://doaj.org/article/926a35ecbeb94936ac48c03e9a0b5526
Autor:
Sudpreeda Chainitikun, Jose Rodrigo Espinosa Fernandez, James P Long, Toshiaki Iwase, Kumiko Kida, Xiaoping Wang, Sadia Saleem, Bora Lim, Vicente Valero, Naoto T Ueno
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0250057 (2021)
BackgroundThe current use of targeted therapy plus neoadjuvant chemotherapy for inflammatory breast cancer (IBC) is based on data extrapolated from studies in non-IBC. We conducted a systematic review to determine whether neoadjuvant chemotherapy plu
Externí odkaz:
https://doaj.org/article/eacfe47c019745d09765a013d999b9ec
Autor:
Jangsoon Lee, Huey Liu, Troy Pearson, Toshiaki Iwase, Jon Fuson, Alshad S. Lalani, Lisa D. Eli, Irmina Diala, Debu Tripathy, Bora Lim, Naoto T. Ueno
Publikováno v:
Biomedicines, Vol 9, Iss 7, p 740 (2021)
Human epidermal growth factor receptor (EGFR) 2 (HER2) is overexpressed/amplified in about 25% of all breast cancers, and EGFR is overexpressed in up to 76% and amplified in up to 24% of triple-negative breast cancers (TNBC). Here, we aimed to identi
Externí odkaz:
https://doaj.org/article/cedd88ae516042b3b4bd35ba6d3e15c2
Autor:
Toshiaki Iwase1,2, Parikh, Aaroh3, Dong Wenli4, Yu Shen5, Adams, Daniel L.6, Cha-mei Tang6, Cohen, Evan N.6, Reuben, James M.6, Shrimanker, Tushaar Vishal7, Sudpreeda Chainitikun8, Kumiko Kida9, Raghavendra, Akshara Singareeka10, Sapon, Maryanne E.1, Sahin, Onur1, James, Anjali1, Sridhar, Nithya1, Klopp, Ann H.11, Tripathy, Debasish10, Ueno, Naoto T.2 nueno@cc.hawaii.edu
Publikováno v:
Journal of Cancer. 2024, Vol. 15 Issue 18, p5855-5862. 8p.
Autor:
Faina Nakhlis, Samuel Niman, Naoto T. Ueno, Elizabeth Troll, Sean Ryan, Eren Yeh, Laura Warren, Jennifer Bellon, Beth Harrison, Toshiaki Iwase, H. T. Carisa Le-Petross, Sadia Saleem, Mediget Teshome, Gary J. Whitman, Wendy Woodward, Beth Overmoyer, Sara Tolaney, Meredith Regan, Filipa Lynce, Rachel M. Layman
Publikováno v:
Cancer Research. 83:P4-07
Background: Inflammatory breast cancer (IBC) is associated with a poor prognosis. While many stage III IBC patients (pts) experience a sufficient response to first-line (1L) neoadjuvant chemotherapy (NAC) to permit subsequent surgical therapy, the pr
Autor:
Dennis Wylie, Xiaoping Wang, Jun Yao, Hengyi Xu, Elizabeth A Ferrick-Kiddie, Toshiaki Iwase, Savitri Krishnamurthy, Naoto T Ueno, Alan M Lambowitz
Publikováno v:
medRxiv
Inflammatory breast cancer (IBC) is the most aggressive and lethal breast cancer subtype, but lags in biomarker identification. Here, we used an improved Thermostable Group II Intron Reverse Transcriptase RNA sequencing (TGIRT-seq) method to simultan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14ded9f175e34cba320058efbafe3097
https://europepmc.org/articles/PMC10312853/
https://europepmc.org/articles/PMC10312853/
Autor:
Xiaoping Wang, Takashi Semba, Ganiraju C. Manyam, Jing Wang, Shan Shao, Francois Bertucci, Pascal Finetti, Savitri Krishnamurthy, Lan ThiHanh Phi, Troy Pearson, Jared K. Burks, Evan N. Cohen, James M. Reuben, Fei Yang, Hu Min, Nicholas Navin, Toshiaki Iwase, Yichao Shen, Xiang Zhang, Debu Tripathy, Naoto T. Ueno
Publikováno v:
Cancer Research. 82:PD10-08
Background: Inflammatory breast cancer (IBC) is the most lethal and aggressive form of breast cancer, yet no targeted therapy has been approved specifically for this disease. There is a critical need for innovative treatment approaches for patients w
Autor:
David Bourdon, Alessandra Cunsolo, Brandon Guillory, Megan M. Slade, Giuseppe Di Caro, Alisa Tubbs, Toshiaki Iwase, Naoto T. Ueno
Publikováno v:
Cancer Research. 83:P5-06
Introduction A blood-based biopsy can inform the prognosis for MBC patients when conventional tissue biopsies are not feasible within often biologically heterogeneous sites of metastatic disease. Several anti-Trophoblast cell-surface antigen 2 (TROP2