Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Toshiaki Aikawa"'
Autor:
Yasuharu Shimasaki, Yumi Hayashi, Yosuke Tomioka, Toshiaki Aikawa, Takashi Miki, Hiroaki Okamoto, Tetsuya Ikemoto, Masahiro Takeda
Publikováno v:
Organic Process Research & Development. 20:1615-1620
An efficient method for synthesizing 1-({[(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yloxy]carbonyl}oxy)pyrrolidine-2,5-dione (1), a key building block for HIV protease inhibitors, has been developed. A diphenylprolinol-catalyzed highly enantio- and di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76e569fd02d70a0c598aa62626e8db12
https://doi.org/10.1021/acs.oprd.6b00178
https://doi.org/10.1021/acs.oprd.6b00178
Publikováno v:
Organic Letters. 5:51-54
Nucleophilic reactions of various enol silyl ethers with carbocation species generated from propargyl silyl ethers by the action of a Lewis acid have been developed. The present method is highly useful for the introduction of allenic or enyne functio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88c3f2bb9f923efa91c8fbe1110616e8
https://doi.org/10.1021/ol0271537
https://doi.org/10.1021/ol0271537
Publikováno v:
The Journal of Organic Chemistry. 66:4635-4642
Highly useful carbon-carbon bond forming reactions using stable allenyl, propargyl, or allyl-propargyl hybrid cations have been developed. These carbocations could be generated from silyl 1-(pi-donor)-substituted propargyl ethers by the action of tri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91ab870facd1f84b5c7de8956fd6a139
https://doi.org/10.1021/jo010157p
https://doi.org/10.1021/jo010157p
Publikováno v:
Tetrahedron Letters. 51:2832-2834
A simple and highly C3 selective ring-opening method for 3,4-epoxypiperidines has been developed. We also describe a practical improvement of the C4 selective ring-opening method using the same N -alkyl substituted 3,4-epoxypiperidines. This method p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0dc2e307cfcc5facdd0af8b85100eeff
https://doi.org/10.1016/j.tetlet.2010.03.061
https://doi.org/10.1016/j.tetlet.2010.03.061
Publikováno v:
ChemInform. 32
Highly useful carbon−carbon bond forming reactions using stable allenyl, propargyl, or allyl−propargyl hybrid cations have been developed. These carbocations could be generated from silyl 1-(π-donor)-substituted propargyl ethers by the action of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c4ebe88b83be278fdf4abde31b47cff
https://doi.org/10.1002/chin.200146056
https://doi.org/10.1002/chin.200146056
Autor:
Eiko Ohata, Takako Iseki, Tatsuo Fujino, Satoshi Maeda, Seiki Saito, Toshiaki Aikawa, Teruhiko Ishikawa, Takashi Matsuo
Publikováno v:
ChemInform. 38
Enolate generated from O-(tetrahydropyran-2-yl)hydroxyacetone under thermodynamically controlled conditions (1.3 equiv of NaH, THF, 0 degrees C to rt) was allylated at the carbon bearing the protected hydroxy group with very high regioselectively. Wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2db282171b848c0d0851435a220b4535
https://doi.org/10.1002/chin.200721045
https://doi.org/10.1002/chin.200721045
Publikováno v:
Organic letters. 8(17)
[reaction: see text] Carbamates or sulfonamides have proven to regioselectively attack 2-propynyl-allyl hybrid cations, generated by the action of TMSOTf on 4-(trimethylsioxy)hex-5-en-2-ynoates, to afford conjugated 6-aminohex-4-en-2-ynoates in which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4f2697a7efd0baa592b36a9c491169e
https://pubmed.ncbi.nlm.nih.gov/16898841
https://pubmed.ncbi.nlm.nih.gov/16898841
Publikováno v:
Organic letters. 6(14)
[reaction: see text] This paper describes a novel method to synthesize a quinoline backbone by incorporating allenyl cations into a catalytic intramolecular Friedel-Crafts reaction. The initial products were isomerized and aromatized upon treatment w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0d7f3eb262d3c55037b2223da48a961
https://pubmed.ncbi.nlm.nih.gov/15228279
https://pubmed.ncbi.nlm.nih.gov/15228279
Publikováno v:
Organic letters. 6(9)
[reaction: see text] Chiral C(4)-substituted (E)- or (Z)-1-alkynyl-1-trimethylsilyloxy-2-butene systems provide anti-(Z) or syn-(Z) conjugated dienyne, with a very high level of stereocontrol, on treatment with BF(3).OEt(2) in CH(2)Cl(2) at -50 degre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2860b49912db977bf1740b919c29b2a7
https://pubmed.ncbi.nlm.nih.gov/15101744
https://pubmed.ncbi.nlm.nih.gov/15101744
Publikováno v:
ChemInform. 34
Nucleophilic reactions of various enol silyl ethers with carbocation species generated from propargyl silyl ethers by the action of a Lewis acid have been developed. The present method is highly useful for the introduction of allenic or enyne functio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31726bfca4c45dd915607c541948e279
https://doi.org/10.1002/chin.200321062
https://doi.org/10.1002/chin.200321062