Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Toshi Iwama"'
Autor:
Motonobu Satoh, Akira Hakura, Masao Takeuchi, Toshi Iwama, Haruhiko Kuno, Yumiko Nakagaito, Touho Yoshida
Publikováno v:
In Vitro Cellular & Developmental Biology - Animal. 34:585-592
We have established a multipotent clonal cell line, named MEB5, from embryonic mouse forebrains after the infection of a retrovirus carrying E7 oncogene of human papillomavirus type 16. MEB5 cells proliferated in serum-free, epidermal growth factor (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3262bd1135def9dedbce2488d23a2d0
https://doi.org/10.1007/s11626-998-0119-5
https://doi.org/10.1007/s11626-998-0119-5
Autor:
Norikazu Tamura, Yoshihiro Matsushita, Toshi Iwama, Katsumi Itoh, Shoji Kishimoto, Setsuo Harada
Publikováno v:
ChemInform. 23
(S)-2-Amino-3-(2,5-dihydro-5-oxo-4-isoxazolyl)propanoic acid (TAN-950 A (1)) is a novel amino acid antibiotic which shows a high affinity for glutamate receptors of the central nervous system. To improve the affinity for glutamate receptors, the stru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f416940f0797cfb3a3579bc88c75d8f
https://doi.org/10.1002/chin.199215315
https://doi.org/10.1002/chin.199215315
Autor:
Richard J. Miller, James R. Brorson, Toshi Iwama, Charles J. Marcuccilli, Vytautas P. Bindokas, Jane C. Chisholm
Publikováno v:
Journal of neurobiology. 26(3)
Although a neurotoxic role has been postulated for the beta-amyloid protein (beta AP), which accumulates in brain tissues in Alzheimer's disease, a precise mechanism underlying this toxicity has not been identified. The peptide fragment consisting of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cc425c48867e3c8dad0ba703a2f1bd6
https://pubmed.ncbi.nlm.nih.gov/7775966
https://pubmed.ncbi.nlm.nih.gov/7775966
Publikováno v:
Chemicalpharmaceutical bulletin. 40(2)
(S)-2-Amino-3-(2,5-dihydro-5-oxo-3-isoxazolyl)propanoic acid, (3a) and its analogs (3b--h) were prepared and evaluated for glutamate receptor-agonistic and antifungal activities. Several (S)- and (R)-2-amino-3-isoxazolylpropanoic acid derivatives (3a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::681bc2a06bfa8dce9aa3e7e47d32fdff
https://pubmed.ncbi.nlm.nih.gov/1318791
https://pubmed.ncbi.nlm.nih.gov/1318791
Autor:
Toshi Iwama, Shoji Kishimoto, Setsuo Harada, Yoshihiro Matsushita, Katsumi Itoh, Norikazu Tamura
Publikováno v:
Chemicalpharmaceutical bulletin. 39(5)
(S)-2-Amino-3-(2,5-dihydro-5-oxo-4-isoxazolyl)propanoic acid (TAN-950 A (1)) is a novel amino acid antibiotic which shows a high affinity for glutamate receptors of the central nervous system. To improve the affinity for glutamate receptors, the stru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be75cafff310b739bea239a329e701a2
https://pubmed.ncbi.nlm.nih.gov/1655291
https://pubmed.ncbi.nlm.nih.gov/1655291
Publikováno v:
Japanese Journal of Pharmacology. 73:85
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07b88d386c276000c2f1fcfa314129c9
https://doi.org/10.1016/s0021-5198(19)44847-6
https://doi.org/10.1016/s0021-5198(19)44847-6
Publikováno v:
Japanese Journal of Pharmacology. 55:408
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::134b0374243f3de607fe9aafc8081603
https://doi.org/10.1016/s0021-5198(19)39612-x
https://doi.org/10.1016/s0021-5198(19)39612-x
Publikováno v:
Journal of Pharmacobio-Dynamics. 10:564-570
Intracellular recordings of the CA3 pyramidal neurons in the guinea pig hippocampus were made in vitro. U-50 488H (100 microM), a selective opioid kappa agonist, decreased the synaptic response produced by stimulation of the mossy fibers but did not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09794d6023bf0d932157fc59ad6e0e49
https://doi.org/10.1248/bpb1978.10.564
https://doi.org/10.1248/bpb1978.10.564
Autor:
Toshi Iwama, T. Nakazawa, Kiyomi Yamatsu, T. Wada, T. Kaneko, M. Satoh, Masuhiro Ikeda, Hiroshi Takagi
Publikováno v:
Life sciences. 33
Analgesic effects of dynorphin and dynorphin-(1-13) injected into various regions of the CNS of rats were investigated using the tail pinch method. Dynorphin and dynorphin-(1-13) produced a dose-dependent analgesic effect when injected into the third
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7a69e963913ed23f3feebe19663ec50
https://pubmed.ncbi.nlm.nih.gov/6141507
https://pubmed.ncbi.nlm.nih.gov/6141507
Publikováno v:
Neuropeptides. 5(4-6)
Kyotorphin(KTP) and its analog D-kyotorphin(D-KTP) which is resistant to enzyme degradation produced dose-dependent analgesic effects in the tail-pinch test when applied locally to the periaqueductal gray (PAG), nucleus reticularis paragigantocellula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::392764dc4a0c250cf5ae3fc1f9e3e48b
https://pubmed.ncbi.nlm.nih.gov/4000414
https://pubmed.ncbi.nlm.nih.gov/4000414