Zobrazeno 1 - 10
of 584
pro vyhledávání: '"Toscan A"'
Autor:
Cara E. Toscan, Hannah McCalmont, Amir Ashoorzadeh, Xiaojing Lin, Zhe Fu, Louise Doculara, Hansen J. Kosasih, Roxanne Cadiz, Anthony Zhou, Sarah Williams, Kathryn Evans, Faezeh Khalili, Ruilin Cai, Kristy L. Yeats, Andrew J. Gifford, Russell Pickford, Chelsea Mayoh, Jinhan Xie, Michelle J. Henderson, Toby N. Trahair, Adam V. Patterson, Jeff B. Smaill, Charles E. de Bock, Richard B. Lock
Publikováno v:
Blood Cancer Journal, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematological malignancy that expresses high levels of the enzyme aldo-keto reductase family 1 member C3 (AKR1C3). To exploit this finding, we developed a novel prodrug, ACHM-025,
Externí odkaz:
https://doaj.org/article/6345a011fd5e4b7dbeced8196c76971a
Autor:
Peter Truong, Sylvie Shen, Swapna Joshi, Md Imtiazul Islam, Ling Zhong, Mark J. Raftery, Ali Afrasiabi, Hamid Alinejad-Rokny, Mary Nguyen, Xiaoheng Zou, Golam Sarower Bhuyan, Chowdhury H. Sarowar, Elaheh S. Ghodousi, Olivia Stonehouse, Sara Mohamed, Cara E. Toscan, Patrick Connerty, Purvi M. Kakadia, Stefan K. Bohlander, Katharine A. Michie, Jonas Larsson, Richard B. Lock, Carl R. Walkley, Julie A. I. Thoms, Christopher J. Jolly, John E. Pimanda
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Hypomethylating agents (HMAs) are frontline therapies for Myelodysplastic Neoplasms (MDS) and Acute Myeloid Leukemia (AML). However, acquired resistance and treatment failure are commonplace. To address this, we perform a genome-wide CRISPR-
Externí odkaz:
https://doaj.org/article/73815292edce4c1d9476e3fd55ac41f7
A group of cooperative aerial robots can be deployed to efficiently patrol a terrain, in which each robot flies around an assigned area and shares information with the neighbors periodically in order to protect or supervise it. To ensure robustness,
Externí odkaz:
http://arxiv.org/abs/2209.06968
Publikováno v:
Journal of Applied Poultry Research, Vol 33, Iss 3, Pp 100448- (2024)
SUMMARY: Considerable variability has been reported for soybean meal (SBM) nutrient and energy content and protein and amino acid (AA) digestibility. Furthermore, analytical variability among labs can introduce bias in feedstuff valuation. Energy val
Externí odkaz:
https://doaj.org/article/6f56fdc7da2443c7adb0d8eb50614a49
Publikováno v:
In Journal of Applied Poultry Research September 2024 33(3)
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
M Toscan, AD Ferrazza, LC Fauth, LG Brito, MCC Erig, AH Schuck, CT Burtet, RM Berthier, BG Pozzi, EW Silva
Publikováno v:
Hematology, Transfusion and Cell Therapy, Vol 45, Iss , Pp S565-S566 (2023)
Introdução: A vitamina B12 não é sintetizada em seres humanos e sua única fonte nutricional são produtos de origem animal. A anemia devido à deficiência dessa vitamina é uma condição rara na infância e geralmente é decorrente da insufici
Externí odkaz:
https://doaj.org/article/3bfb795a923b4779871f8bf99b4cce82
Autor:
Neckel, Alcindo, Oliveira, Marcos L.S., Maculan, Laércio Stolfo, Adelodun, Bashir, Toscan, Paloma Carollo, Bodah, Brian William, Moro, Leila Dal, Silva, Luis F.O.
Publikováno v:
In Marine Pollution Bulletin February 2023 187
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Tina Keller-Costa, Lydia Kozma, Sandra G. Silva, Rodolfo Toscan, Jorge Gonçalves, Asunción Lago-Lestón, Nikos C. Kyrpides, Ulisses Nunes da Rocha, Rodrigo Costa
Publikováno v:
Microbiome, Vol 10, Iss 1, Pp 1-20 (2022)
Abstract Background The role of bacterial symbionts that populate octocorals (Cnidaria, Octocorallia) is still poorly understood. To shed light on their metabolic capacities, we examined 66 high-quality metagenome-assembled genomes (MAGs) spanning 30
Externí odkaz:
https://doaj.org/article/5cfb1666efd24c70a07b1da831e9c434