Výsledky vyhledávání - "Toru Shimokubo"

Differences in 24-h blood pressure profile of Japanese hypertensive patients under ARB treatment

Autor: Noboru Tamaki, Naoto Yokota, Takuma Etoh, Yusuke Ohya, Toru Shimokubo, Seigo Nakada, Toshihiro Kita, Atsushi Sakima, Kazuo Kitamura, Shuichi Takishita

Publikováno v: Clinical and Experimental Hypertension. 37:574-579

Blood pressure (BP) control throughout the entire day is recommended for cardiovascular protection. Angiotensin-II receptor blockers (ARBs) are widely used in hypertensive patients because of beneficial class effects. It is uncertain, however, whethe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d02111ebcda7c0a657375db89537b911
https://doi.org/10.3109/10641963.2015.1026042

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Adrenomedullin in the gastrointestinal tract. Distribution and gene expression in rat and augmented gastric adrenomedullin after fasting

Autor: Hisayuki Matsuo, Tanenao Eto, Haruhiko Inatsu, Toru Shimokubo, Junichiro Sakata, Akinobu Sumiyoshi, Kazuo Kitamura, Michitaka Kitani, Yujiro Asada, Kenji Kangawa

Publikováno v: Journal of Gastroenterology. 33:828-834

The aim of this study was to investigate the regional distribution, molecular forms, and gene expression of adrenomedullin in the rat gastrointestinal tract and to examine physiological changes in gastric adrenomedullin after 24-h fasting. The tissue

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3c2b0db5de5f638c2ff5f0ffceceda3
https://doi.org/10.1007/s005350050183

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Diuretics enhance effects of increased dose of candesartan on ambulatory blood pressure reduction in Japanese patients with uncontrolled hypertension treated with medium-dose angiotensin II receptor blockers

Autor: Atsushi Sakima, Toshihiro Kita, Kazuo Kitamura, Shuichi Takishita, Toru Shimokubo, Seigo Nakada, Noboru Tamaki, Yusuke Ohya, Takuma Etoh, Naoto Yokota

Publikováno v: Clinical and experimental hypertension (New York, N.Y. : 1993). 36(1)

Although blockade of the renin-angiotensin system by increasing the dose of angiotensin II receptor blockers (ARBs) is recommended to achieve clinical benefits in terms of blood pressure (BP) control and cardiovascular and renal outcomes, the effect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77be85824e04dbd73711860524f6aea5
https://pubmed.ncbi.nlm.nih.gov/23713902

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Adrenomedullin: Changes in Circulating and Cardiac Tissue Concentration in Dahl Salt-Sensitive Rats on a High-Salt Diet

Autor: Toru Shimokubo, Kazuo Kitamura, Hisayuki Matsuo, Tanenao Eto, Junichiro Sakata, Kenji Kangawa

Publikováno v: Clinical and Experimental Hypertension. 18:949-961

Adrenomedullin (AM), a novel hypotensive peptide, is suggested to be involved in defense mechanisms against hypertension, however, the detail mechanisms have not been clarified. To elucidate whether AM synthesis would be altered in a salt dependent h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e23ebaccd65baf86f58e0bbf2978ea4a
https://doi.org/10.3109/10641969609097910

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Plasma adrenomedullin in patients with primary aldosteronism

Autor: Yuichiro Ishiyama, Johji Kato, Toru Shimokubo, Kenji Kuwasako, Kazuo Kitamura, Shigeru Nakamura, Yoshinari Ichiki, Miho Tanaka, Tanenao Eto, Kenji Kangawa

Publikováno v: American Journal of Hypertension. 8:997-1000

Adrenomedullin (AM) is a novel hypotensive peptide originally isolated from the pheochromocytoma tissue of humans. To examine the pathophysiological role of AM in primary aldosteronism (PA), the plasma concentration of AM in patients with PA was meas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf4ff7c75aac031fa2a1f532311a6890
https://doi.org/10.1016/0895-7061(95)00217-0

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Distribution and characterization of immunoreactive rat adrenomedullin in tissue and plasma

Autor: Kazuo Kitamura, Masatoshi Nishizono, Hisayuki Matsuo, Junichiro Sakata, Tanenao Eto, Kenji Kangawa, Toru Shimokubo, Yoshinari Iehiki

Publikováno v: FEBS Letters. 352:105-108

Adrenomedullin is a new bioactive peptide recently isolated from pheochromocytoma. We report on the rat adrenomedullin distribution and molecular forms in various tissues and plasma. Using a sensitive radioimmunoassay system for rat adrenomedullin, h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae9847f2eb43df11f731098ab14420c2
https://doi.org/10.1016/0014-5793(94)00928-7

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[A case of mixed infection by Nocardia asteroides and Mycobacterium tuberculosis]

Autor: Toru, Shimokubo, Jun-ichi, Ashitani, Toshihiko, Ihi, Toshinobu, Higa, Kenshi, Kumamoto

Publikováno v: Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society. 40(8)

A 55-year-old man with diabetes mellitus was admitted to our hospital because of abnormal shadows in his chest radiographs. Both chest radiography and CT revealed infiltrative shadows in the right upper lung field. Repeated sputum smears showed no my

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::eefcd6a9af9ea30c8990db11cabb5059
https://pubmed.ncbi.nlm.nih.gov/12428403

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Molecular cloning and biological activities of rat adrenomedullin, a hypotensive peptide

Autor: Tanenao Eto, Toru Shimokubo, Kenji Kangawa, Shigeru Nakamura, Junichiro Sakata, Hisayuki Matsuo, Kazuo Kitamura

Publikováno v: Biochemical and biophysical research communications. 195(2)

Adrenomedullin is a new hypotensive peptide recently identified in human pheochromocytoma arising from adrenal medulla. We report here the cDNA encoding a rat adrenomedullin precursor. The precursor is 185 amino acids in length, including a 21 residu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11a55f92092fd29b3c088528500df9fd
https://pubmed.ncbi.nlm.nih.gov/7690563

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