Zobrazeno 1 - 10
of 201
pro vyhledávání: '"Toru Okamoto"'
Autor:
Toshihiro Sakata, Sachiyo Yoshio, Taiji Yamazoe, Taizo Mori, Eiji Kakazu, Yoshihiko Aoki, Nobuyoshi Aoyanagi, Toru Okamoto, Takanori Ito, Hidenori Toyoda, Takumi Kawaguchi, Yoshihiro Ono, Yu Takahashi, Akinobu Taketomi, Tatsuya Kanto
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionNatural killer (NK) cells play a pivotal role in immune surveillance in the liver. We aimed to identify potential targets for NK cell-mediated immune intervention by revealing the functional molecules on NK cells in HCC patients.MethodsTo
Externí odkaz:
https://doaj.org/article/de5b2ce4f5254880b08b1d33681469b5
Autor:
Shohei Minami, Tomohiro Kotaki, Yusuke Sakai, Shinya Okamura, Shiho Torii, Chikako Ono, Daisuke Motooka, Rina Hamajima, Ryotaro Nouda, Jeffery A. Nurdin, Moeko Yamasaki, Yuta Kanai, Hirotaka Ebina, Yusuke Maeda, Toru Okamoto, Taro Tachibana, Yoshiharu Matsuura, Takeshi Kobayashi
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 4 (2024)
ABSTRACTSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) utilizes several host proteases to cleave the spike (S) protein to enter host cells. SARS-CoV-2 S protein is cleaved into S1 and S2 subunits by furin, which is closely involved in t
Externí odkaz:
https://doaj.org/article/52bcfaa75fde4976b2cff269b2a83cf6
Autor:
Junya Okabe, Takahiro Kodama, Yu Sato, Satoshi Shigeno, Takayuki Matsumae, Kazuma Daiku, Katsuhiko Sato, Teppei Yoshioka, Minoru Shigekawa, Masaya Higashiguchi, Shogo Kobayashi, Hayato Hikita, Tomohide Tatsumi, Toru Okamoto, Takashi Satoh, Hidetoshi Eguchi, Shizuo Akira, Tetsuo Takehara
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-15 (2023)
Abstract Background Pancreatitis is known to be an important risk factor for pancreatic ductal adenocarcinoma (PDAC). However, the exact molecular mechanisms of how inflammation promotes PDAC are still not fully understood. Regnase-1, an endoribonucl
Externí odkaz:
https://doaj.org/article/068d42afa9724d5e91d235e206d129dd
Autor:
Yoshihiro Samune, Akatsuki Saito, Tadahiro Sasaki, Ritsuko Koketsu, Narinee Srimark, Juthamas Phadungsombat, Masaru Yokoyama, Osamu Kotani, Hironori Sato, Atsushi Yamanaka, Saori Haga, Toru Okamoto, Takeshi Kurosu, Emi E Nakayama, Tatsuo Shioda
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 18, Iss 1, p e0011885 (2024)
Dengue is a mosquito-borne disease that has spread to over 100 countries. Its symptoms vary from the relatively mild acute febrile illness called dengue fever to the much more severe dengue shock syndrome. Dengue is caused by dengue virus (DENV), whi
Externí odkaz:
https://doaj.org/article/41fb754db4244c05a9a5a5e6dfd43ecb
Autor:
Shohei Minami, Naomi Matsumoto, Hiroko Omori, Yutaka Nakamura, Shigeyuki Tamiya, Ryotaro Nouda, Jeffery A. Nurdin, Moeko Yamasaki, Tomohiro Kotaki, Yuta Kanai, Toru Okamoto, Taro Tachibana, Hiroshi Ushijima, Takeshi Kobayashi, Shintaro Sato
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes severe acute respiratory symptoms in humans. Controlling the coronavirus disease pandemic is a worldwide priority. The number of SARS-CoV-2 studies has dramatically increase
Externí odkaz:
https://doaj.org/article/87258b246f2a436185b38dcf74f2a65a
Autor:
Brandon Havranek, Graeme Walker Lindsey, Yusuke Higuchi, Yumi Itoh, Tatsuya Suzuki, Toru Okamoto, Atsushi Hoshino, Erik Procko, Shahidul M. Islam
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-16 (2023)
Abstract SARS-CoV-2, especially B.1.1.529/omicron and its sublineages, continues to mutate to evade monoclonal antibodies and antibodies elicited by vaccination. Affinity-enhanced soluble ACE2 (sACE2) is an alternative strategy that works by binding
Externí odkaz:
https://doaj.org/article/9f60e82e652f473a945c00b3838f25bc
Autor:
Nagisa Tokunoh, Shigeyuki Tamiya, Masato Watanabe, Toru Okamoto, Jessica Anindita, Hiroki Tanaka, Chikako Ono, Toshiro Hirai, Hidetaka Akita, Yoshiharu Matsuura, Yasuo Yoshioka
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionVaccinations are ideal for reducing the severity of clinical manifestations and secondary complications of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); however, SARS-CoV-2 continues to cause morbidity and mortality worldw
Externí odkaz:
https://doaj.org/article/f914d127f33843f0b67bac0828d33e89
Autor:
Naoko Nemoto, Hitoshi Kawanabe, Kazunori Fukui, Akihiko Oyama, Toru Okamoto, Kazuhiro Shimamura
Publikováno v:
Journal of Clinical Medicine, Vol 12, Iss 23, p 7254 (2023)
Sleep-disordered breathing affects children’s growth and development, mental health, and learning ability. Postoperative scarring causes anteroposterior and vertical developmental disorders of the maxilla. Obstructive apnea is likely to occur due t
Externí odkaz:
https://doaj.org/article/6d535f017fb04669ab664971ffe4dfef
Autor:
Emi Sano, Tatsuya Suzuki, Rina Hashimoto, Yumi Itoh, Ayaka Sakamoto, Yusuke Sakai, Akatsuki Saito, Daisuke Okuzaki, Daisuke Motooka, Yukiko Muramoto, Takeshi Noda, Tomohiko Takasaki, Jun-Ichi Sakuragi, Shohei Minami, Takeshi Kobayashi, Takuya Yamamoto, Yasufumi Matsumura, Miki Nagao, Toru Okamoto, Kazuo Takayama
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-9 (2022)
Bronchial organoids (BO) and BO-derived air-liquid interface models (BO-ALI) are used to model SARS-CoV-2 infection of human bronchial epithelial cells, reporting that ciliated cells were permissive to the virus, unlike basal cells.
Externí odkaz:
https://doaj.org/article/9cc2cd2c28c541b5a28dd5c6e275c374
Autor:
Yoichi Miyamoto, Yumi Itoh, Tatsuya Suzuki, Tomohisa Tanaka, Yusuke Sakai, Masaru Koido, Chiaki Hata, Cai-Xia Wang, Mayumi Otani, Kohji Moriishi, Taro Tachibana, Yoichiro Kamatani, Yoshihiro Yoneda, Toru Okamoto, Masahiro Oka
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-15 (2022)
The SARS-CoV-2 ORF6, an antagonist of interferon-mediated antiviral signaling, directly binds to STAT1 and prevents its nuclear localization.
Externí odkaz:
https://doaj.org/article/ab4f7dbe07584f11b248243e57c5400c