Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Toru Komai"'
Autor:
Chang Paik, William C. Eckelman, Toru Komai, W. J. Rzeszotarski, Raymond E. Gibson, J. Krijn Mazaitis, Richard C. Reba, Victor Jiang
Publikováno v:
Principles of Radiopharmacology ISBN: 9780429288760
Principles of Radiopharmacology
Principles of Radiopharmacology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a91b003675f7e7375e30ff779132d20
https://doi.org/10.1201/9780429288760-3
https://doi.org/10.1201/9780429288760-3
Autor:
J. Krijn Mazaitis, William C. Eckelman, W. J. Rzeszotarski, Raymond E. Gibson, Toru Komai, Victor Jiang, Richard C. Reba, Chang Paik
Publikováno v:
Principles of Radiopharmacology ISBN: 9780429288715
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f7d95c76a7d09de53842ef010aa7a60
https://doi.org/10.1201/9780429288715-13
https://doi.org/10.1201/9780429288715-13
Autor:
Kiyomi Ito, Minoru Uchiyama, Yuichi Sugiyama, Toshihiko Ikeda, Haruo Iwabuchi, Michi Ishigam, Toru Komai, Tomoko Kondo, Shin-ichi Inoue, Wataru Takasaki
Publikováno v:
Pharmaceutical Research. 18:622-631
Purpose. To evaluate an interaction between simvastatin and itraconazole in in vitro studies and to attempt a quantitative prediction of in vivo interaction in humans.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::070efcfae0b3073dc1ff53c9fe8a75db
https://doi.org/10.1023/a:1011077109233
https://doi.org/10.1023/a:1011077109233
Autor:
Toru Komai
Publikováno v:
Japanese poultry science. 33:268-272
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::477d150da7b34e3ac0af724b541033b9
https://doi.org/10.2141/jpsa.33.268
https://doi.org/10.2141/jpsa.33.268
Autor:
Toru Komai, Sayoko Akiyama, Ryuichiro Nishigaki, Masayo Yamazaki, Michi Ishigami, Yuichi Sugiyama, Taro Tokui
Publikováno v:
Drug Metabolism and Pharmacokinetics. 10:108-111
Among the HMG-CoA reductase inhibitors, pravastatin which is hydrophilic in nature, has been shown to exhibit relatively specific inhibition of cholesterol synthesis in the liver. As one of the reasons for this relatively specific pharmacological act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e93b61a4657154afab8071c1a110065a
https://doi.org/10.2133/dmpk.10.supplement_108
https://doi.org/10.2133/dmpk.10.supplement_108
Publikováno v:
Pharmaceutical Research. 12:1741-1745
Purpose. We have already demonstrated that the HMG-CoA reductase inhibitor, pravastatin is actively taken up by isolated rat hepatocytes via a multispecific anion transporter (Yamazaki et al., Am. J. Physiol. 264, G36-44, (1993)). We further attempte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::483ea29ba82704f4720e9e9e53b6d86d
https://doi.org/10.1023/a:1016226024587
https://doi.org/10.1023/a:1016226024587
Autor:
Toru Komai
Publikováno v:
Japanese poultry science. 32:52-71
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b265db75605af8c8994686f66e11fb7
https://doi.org/10.2141/jpsa.32.52
https://doi.org/10.2141/jpsa.32.52
Autor:
Naoyuki Maeda, Chitose Kuroiwa, Kazuhiko Sasagawa, Kenji Kawai, Takashi Inoue, Toshihiko Ikeda, Taro Tokui, Toru Komai
Publikováno v:
Pharmaceutical Research. 12:370-375
RS-1541 is a 13-O-palmitoyl derivative of rhizoxin, an inhibitor of tubulin polymerization. After intravenous administration of RS-1541 to mice bearing M5076 sarcoma, the maximal inhibitory effect of RS-1541 on DNA synthesis in the tumor was observed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d938565d3b1795382f4e58a5cc087165
https://doi.org/10.1023/a:1016248417492
https://doi.org/10.1023/a:1016248417492
Autor:
K. Kawai, Y. Tokui, Kazuhiko Sasagawa, Chitose Kuroiwa, Toru Komai, Tomowo Kobayashi, Taro Tokui, Toshihiko Ikeda
Publikováno v:
Biopharmaceutics & Drug Disposition. 15:93-107
The tumour uptake as well as the anti-tumour activity of RS-1541 (palmitoyl rhizoxin), a potent antineoplastic agent, were investigated in mice bearing M5076 sarcoma. After intravenous administration, 14C-RS-1541 preferentially bound to the lipoprote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1de498486806514a1b847c83985f0c24
https://doi.org/10.1002/bdd.2510150202
https://doi.org/10.1002/bdd.2510150202
Publikováno v:
Drug Metabolism and Pharmacokinetics. 9:588-595
The uptake mechanism of tetramethylammonium (TMA) and tetraethylammonium (TEA) ions was investigated using the isolated rat hepatocytes. TMA and TEA were trans ported against concentration gradient into the isolated hepatocytes. The cellular uptake o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ad140a513ef6927eabcf49c9422ffc2
https://doi.org/10.2133/dmpk.9.588
https://doi.org/10.2133/dmpk.9.588