Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Toru Kinugawa"'
Publikováno v:
Journal of cardiac failure. 25(10)
Activation of neurohormonal systems contributes to the progression of heart failure (HF). The mechanism(s) whereby these systems become activated is(are) not fully explained. We determined whether vagal cardiopulmonary baroreflex control of renal sym
Autor:
Chiaki Shigemasa, Masashi Fujita, Toru Kinugawa, Kazuhide Ogino, Masahiko Kato, Osamu Igawa, Ichiro Hisatome, Masafumi Kitakaze, Shuichi Osaki
Publikováno v:
Journal of Cardiac Failure. 12:720-725
Background Adenosine 5′-triphosphate is catabolized to adenosine 5′-monophosphate (AMP), which is further degraded by 2 pathways: deamination to inosine 5′-monophosphate and ammonia by AMP deaminase, or dephosphorylation to adenosine and inorga
Autor:
Masahiro Yamawaki, Hiroaki Tanaka, Yasutaka Yamamoto, Osamu Igawa, Kazuhide Ogino, Toru Kinugawa, Koichi Matsubara, Takashi Matsuura, Fumihiro Ando, Yasushi Tanaka, Chiaki Shigemasa, Ichiro Hisatome, Rei Yamamoto, Gou Igawa, Tadasu Ikeda, Yoko Tomikura, Akira Takeda
Publikováno v:
Internal Medicine. 42:788-792
OBJECTIVE The aim of this study was to investigate whether or not the purine degradation in the skeletal muscle during forearm exercise is augmented in patients with diabetes mellitus (DM). METHODS We used the semi-ischemic forearm test to examine th
Autor:
Masahiko Kato, Osamu Igawa, Yoko Tomikura, Masaki Shimoyama, Kazuhide Ogino, Chiaki Shigemasa, Ichiro Hisatome, Toru Kinugawa, Shuichi Osaki
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 29:1060-1065
Summary 1. Alacepril is a long-acting, sulphydryl-containing angiotensin-converting enzyme inhibitor. Data are limited regarding the effects of alacepril on exercise tolerance in patients with chronic heart failure (CHF). The aim of the present study
Autor:
Kazuhide Ogino, Osamu Igawa, Yoko Tomikura, John P. Bilezikian, Yoshiyuki Furuse, Masahiko Kato, Toru Kinugawa, Shuichi Osaki, Kazuyoshi Ogura, Kazuhiko Uchida, Yoshiharu Kinugasa, Chiaki Shigemasa, Ichiro Hisatome, Masaki Shimoyama
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 87:4722-4727
PTHrP is produced in a wide variety of different cells, including cardiomyocytes. Its production is augmented by mechanical and neurohumoral stimulation, and PTHrP has positive chronotropic and vasodilatory effects. Thus, in the heart, PTHrP has the
Autor:
Shiro Ikawa, Kazuhiko Uchida, Masahiko Kato, Osamu Igawa, Yoshiyuki Furuse, Toru Kinugawa, Masaki Shimoyama, Chiaki Shigemasa, Shuichi Osaki, Kazuhide Ogino, Ichiro Hisatome, Akihiro Endo
Publikováno v:
Cardiovascular Drugs and Therapy. 16:215-220
Troglitazone increased cardiac output and stroke volume, as a result of decreased peripheral resistance, in diabetic patients with normal cardiac function. The cardiovascular effects of troglitazone in patients with heart failure are unknown. The aim
Publikováno v:
International Heart Journal. 52:398-400
A 33-year-old Japanese man with atrial tachycardia visited our clinic. He regularly consumed daily alcohol with cola, one cup of regular coffee, and a candy containing 0.7 mg of caffeine per tablet. After stopping his caffeine intake, his arrhythmia
Autor:
Kazuhide Ogino, Ichiro Hisatome, Chiaki Shigemasa, Akira Otahara, Yasutaka Yamamoto, Toshihiro Hamada, Toru Kinugawa, Syuichi Ozaki, Osamu Igawa, Tetsuya Yamamoto, Masako Furuse, Kazuhiko Sonoyama
Publikováno v:
Gout and Nucleic Acid Metabolism. 24:31-37
Autor:
Ryoichi Sato, Tadashi Urashima, Toru Kinugawa, Kaoru Ikeda, Osamu Igawa, Jiro Miyamoto, Yasunori Tanaka, Kazuhide Ogino, Akio Yoshida, Yumi Yamanouchi, Yasutaka Kurata, Norihito Sasaki, Chiaki Shigemasa, Ichiro Hisatome
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1418(2):320-334
Objective: To study the interaction between salicylate and class 1 antiarrhythmic agents. Methods: The effects of salicylate on class 1 antiarrhythmic agent-induced tonic and phasic block of the Na+ current (INa) of ventricular myocytes and the upstr
Autor:
Masahiko Kato, Chiaki Shigemasa, Akihiro Endo, Ichiro Hisatome, Osamu Igawa, Shuichi Osaki, Toru Kinugawa, Edward W. Holmes, Tatsuo Kato, Kazuhide Ogino
Publikováno v:
Metabolism. 48:484-488
Plasma levels of ammonia and hypoxanthine (HX) can be indices of purine nucleotide degradation. The present study determined if patients with heart failure (HF) have altered exercise plasma ammonia and HX levels relative to the peak work rate perform