Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Toru Kanke"'
Autor:
Takashi Nishimura, Makoto Mitsunaga, Ryoichi Sawada, Masayuki Saruta, Hisataka Kobayashi, Noriko Matsumoto, Toru Kanke, Hiroyuki Yanai, Koji Nakamura
Publikováno v:
Cancer Medicine, Vol 8, Iss 18, Pp 7781-7792 (2019)
Abstract Photoimmunotherapy (PIT) is a new type of tumor‐specific treatment utilizing monoclonal antibody (mAb)‐photosensitizer conjugates and near‐infrared (NIR) light irradiation. One potential PIT target, the type I transmembrane protein TRO
Externí odkaz:
https://doaj.org/article/59a29a6328554bffa4cc970a7b9cd63c
Autor:
Hideo Kohka Takahashi, Toru Kanke, Keyue Liu, Tadashi Yoshino, Toshiaki Sendo, Noriaki Tanaka, Masahiro Nishibori
Publikováno v:
Journal of Pharmacological Sciences, Vol 104, Iss 2, Pp 183-186 (2007)
Adenosine inhibited interleukin (IL)-18 production in lipopolysaccharide (LPS)-stimulated monocytes. The action of adenosine was antagonized by an adenosine A2A-receptor (A2AR) antagonist and was mimicked by an A2AR agonist, suggesting that the stimu
Externí odkaz:
https://doaj.org/article/30748c376d5f46539151fabd08aa9fcc
Publikováno v:
Journal of Pharmacological Sciences, Vol 97, Iss 1, Pp 38-42 (2005)
PAR-2 is the second member of the family of proteinase-activated receptors activated by trypsin, tryptase, and several other serine proteinases. In order to evaluate the therapeutic potential for PAR-2, we have performed studies on PAR-2-mediated sig
Externí odkaz:
https://doaj.org/article/00b175c871794a93b90fddd08d73d66c
Autor:
Toshiaki Takizawa, Masaki Tamiya, Takuya Hara, Jiro Matsumoto, Naohiro Saito, Toru Kanke, Junichi Kawagoe, Yukio Hattori
Publikováno v:
Journal of Pharmacological Sciences, Vol 98, Iss 1, Pp 99-102 (2005)
Protease-activated receptor 2 (PAR2) belongs to the PAR family (PAR1 to PAR4), which is activated by serine proteases (trypsin, tryptase, etc.). In this study, we evaluated the role of PAR2 in allergic inflammation of airways using PAR2-deficient (PA
Externí odkaz:
https://doaj.org/article/c4830d5e02724128abeb2f5e87749126
Autor:
Masayuki Saruta, Koji Nakamura, Hiroyuki Yanai, Hisataka Kobayashi, Takashi Nishimura, Noriko Matsumoto, Makoto Mitsunaga, Toru Kanke, Ryoichi Sawada
Publikováno v:
Cancer Medicine, Vol 8, Iss 18, Pp 7781-7792 (2019)
Cancer Medicine
Cancer Medicine
Photoimmunotherapy (PIT) is a new type of tumor‐specific treatment utilizing monoclonal antibody (mAb)‐photosensitizer conjugates and near‐infrared (NIR) light irradiation. One potential PIT target, the type I transmembrane protein TROP2, is ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1a19b2381664c04fa8df830e607c22a
https://doaj.org/article/59a29a6328554bffa4cc970a7b9cd63c
https://doaj.org/article/59a29a6328554bffa4cc970a7b9cd63c
Publikováno v:
Cancer Research. 79:1535-1535
Delta-like 1 homolog (DLK-1) is a type I transmembrane protein with 6 tandem EGF-like motifs in extracellular region. In fetal development, DLK-1 is expressed at high levels in undifferentiated, highly proliferative tissues, such as, liver, kidney, s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e8cdd94b95c7d508decb94918a3b031
https://doi.org/10.1158/1538-7445.am2019-1535
https://doi.org/10.1158/1538-7445.am2019-1535
Publikováno v:
British Journal of Pharmacology. 158:1695-1704
Here we have examined the effects of the novel peptide antagonist N-[1-(2,6-dichlorophenyl)methyl]-3-(1-pyrrolidinylmethyl)-1H-indol-5-yl]aminocarbonyl}-glycinyl-L-lysinyl-L-phenylalanyl-N-benzhydrylamide (K-14585) on proteinase-activated receptor (P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc2ed964abc696232b28dbefacb3f18c
https://doi.org/10.1111/j.1476-5381.2009.00415.x
https://doi.org/10.1111/j.1476-5381.2009.00415.x
Autor:
Toru Kanke, Hiromi Iwagaki, Hideo Takahashi, Tadashi Yoshino, Noriaki Tanaka, Toshiaki Sendo, Ryosuke Hamano, Masahiro Nishibori, Keyue Liu
Publikováno v:
Shock. 29:154-159
LPS stimulates CD14/Toll-like receptor (TLR) 4, leading to induce TNF-alpha production. Cell-to-cell interaction through the engagement between intercellular adhesion molecule (ICAM) 1 on monocytes and its ligand on T cells has been suggested to play
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::affaf76281fe124cdeb1760a898bc2da
https://doi.org/10.1097/shk.0b013e31812385da
https://doi.org/10.1097/shk.0b013e31812385da
Autor:
Naoto Adachi, Keyue Liu, Masahiro Nishibori, Tadashi Yoshino, Hideo Takahashi, Shuji Mori, Toru Kanke, Hidenori Wake, Yasuko Tomono, Norihito Hiraga, Yasuharu Sato
Publikováno v:
Okayama Igakkai Zasshi (Journal of Okayama Medical Association). 120:271-277
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34d53ed1d2c8d4145f083d610c0320b0
https://doi.org/10.4044/joma.120.271
https://doi.org/10.4044/joma.120.271
Autor:
Hiroshi Sadamori, Toru Kanke, Keyue Liu, Toshiaki Sendo, Noriaki Tanaka, Tadashi Yoshino, Ryosuke Hamano, Hiromi Iwagaki, Hideo Takahashi, Takahito Yagi, Masahiro Nishibori
Publikováno v:
European Journal of Pharmacology. 564:204-210
The cell-to-cell interaction through binding of intercellular adhesion molecule (ICAM)-1 on monocytes to their ligands lymphocyte function-associated antigen (LFA)-1 on T-cells plays important roles in cytokine production and T-cell proliferation. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffb181938b63c605a73ead1d7b6f1545
https://doi.org/10.1016/j.ejphar.2007.02.005
https://doi.org/10.1016/j.ejphar.2007.02.005