Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Toru Fukuda"'
Autor:
Chengshan Ma, Toru Fukuda, Hiroki Ochi, Satoko Sunamura, Cheng Xu, Ren Xu, Atsushi Okawa, Shu Takeda
Publikováno v:
Molecular Metabolism, Vol 4, Iss 3, Pp 175-185 (2015)
Objective: Bone mass is maintained through a balance of bone formation and resorption. This homeostatic balance is regulated by various systems involving humoral and local factors. The discovery that the anorexigenic hormone leptin regulates bone mas
Externí odkaz:
https://doaj.org/article/b02a3f96a00b4b929174c125b45afd47
Autor:
Tsuyoshi Sato, Yuichiro Enoki, Yasushi Sakamoto, Kazuhiro Yokota, Masahiko Okubo, Masahito Matsumoto, Naoki Hayashi, Michihiko Usui, Shoichiro Kokabu, Toshihide Mimura, Yoshihiko Nakazato, Nobuo Araki, Toru Fukuda, Yasushi Okazaki, Tatsuo Suda, Shu Takeda, Tetsuya Yoda
Publikováno v:
Heliyon, Vol 1, Iss 1 (2015)
Objective: Donepezil, an inhibitor of acetylcholinesterase (AChE) targeting the brain, is a common medication for Alzheimer's disease. Interestingly, a recent clinical study found that administration of this agent is associated with lower risk of hip
Externí odkaz:
https://doaj.org/article/507f8d320d184a8a83d7cfd3bceb421b
Autor:
Tamotsu Igarashi, Akihiko Kuze, Shinichi Sobue, Aya Yamamoto, Kazuhide Yamamoto, Kei Oyoshi, Keiji Imaoka, Toru Fukuda
Publikováno v:
Geospatial Health, Vol 8, Iss 3 (2014)
In this paper we review the status of new applications research of the Japanese Aerospace Exploration Agency (JAXA) for global health promotion using information derived from Earth observation data by satellites in cooperation with inter-disciplinary
Externí odkaz:
https://doaj.org/article/5443b736ca6b4a3f93a236f5e3d3c9ea
Autor:
Kenichiro Kinouchi, Atsuhiro Ichihara, Motoaki Sano, Ge-Hong Sun-Wada, Yoh Wada, Hiroki Ochi, Toru Fukuda, Kanako Bokuda, Hideaki Kurosawa, Naohiro Yoshida, Shu Takeda, Keiichi Fukuda, Hiroshi Itoh
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e78603 (2013)
The ATPase 6 accessory protein 2 (ATP6AP2)/(pro)renin receptor (PRR) is essential for the biogenesis of active vacuolar H(+)-ATPase (V-ATPase). Genetic deletion of ATP6AP2/PRR causes V-ATPase dysfunction and compromises vesicular acidification. Here,
Externí odkaz:
https://doaj.org/article/83fefe0b3de8487583369a879995f052
Autor:
Yoshimi Tokuzawa, Ken Yagi, Yzumi Yamashita, Yutaka Nakachi, Itoshi Nikaido, Hidemasa Bono, Yuichi Ninomiya, Yukiko Kanesaki-Yatsuka, Masumi Akita, Hiromi Motegi, Shigeharu Wakana, Tetsuo Noda, Fred Sablitzky, Shigeki Arai, Riki Kurokawa, Toru Fukuda, Takenobu Katagiri, Christian Schönbach, Tatsuo Suda, Yosuke Mizuno, Yasushi Okazaki
Publikováno v:
PLoS Genetics, Vol 6, Iss 7, p e1001019 (2010)
Excessive accumulation of bone marrow adipocytes observed in senile osteoporosis or age-related osteopenia is caused by the unbalanced differentiation of MSCs into bone marrow adipocytes or osteoblasts. Several transcription factors are known to regu
Externí odkaz:
https://doaj.org/article/74eb93390b81475ba9f86c0bc03a269b
Autor:
Ken Kurisaki, Akihiko Soyama, Shin Hamauzu, Masahiko Yamada, Shun Yamaguchi, Kunihito Matsuguma, Kerkhof, Enzo, Toru Fukuda, Ryo Toya, Susumu Eguchi
Publikováno v:
Journal of the American College of Surgeons (2563-9021); May2024, Vol. 238 Issue 5, p856-860, 5p
Autor:
Masahito Watanabe, Kazuhiro Umeyama, Kazuaki Nakano, Hitomi Matsunari, Toru Fukuda, Kei Matsumoto, Susumu Tajiri, Shuichiro Yamanaka, Koki Hasegawa, Kazutoshi Okamoto, Ayuko Uchikura, Shuko Takayanagi, Masaki Nagaya, Takashi Yokoo, Hiromitsu Nakauchi, Hiroshi Nagashima
Publikováno v:
Laboratory Investigation. 102:560-569
Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited kidney disease, manifesting as the progressive development of fluid-filled renal cysts. In approximately half of all patients with ADPKD, end-stage renal disease result
Autor:
Shun Yamaguchi, Masaaki Hidaka, Shin Hamauzu, Shinichiro Ono, Masahiko Yamada, Susumu Eguchi, Toru Fukuda, Toshiyuki Tsurumoto, Masataka Uetani, Akihiko Soyama
Publikováno v:
Journal of the American College of Surgeons. 233:686-696
Background Retained surgical items are a serious human error. Surgical sponges account for 70% of retained surgical items. To prevent retained surgical sponges, it is important to establish a system that can identify errors and avoid the occurrence o
Autor:
Ayuko Uchikura, Hitomi Matsunari, A. Wuensch, Shin Enosawa, Kazuaki Nakano, Nikolai Klymiuk, Barbara Kessler, Hiroshi Nagashima, Hiromitsu Nakauchi, Masahito Watanabe, Toru Fukuda, Yutaka Hanazono, Akihiro Umezawa, Kazuhiro Umeyama, Sayaka Yashima, Masaki Nagaya, Mayuko Kurome, Valeri Zakhartchenko, Eckhard Wolf
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance The development of therapies for rare and intractable genetic disorders represents a significant unmet medical need. Disease model pigs characterized by physiological, anatomical, and pathogenetic similarities to humans allow translation
Autor:
Shu Takeda, Kyoko Hashimoto, Yo Mabuchi, Satoko Sunamura, Hiroki Ochi, Mitsuru Futakuchi, Keisuke Ae, Kenta Yao, Toru Fukuda, Atsushi Okawa, Nobuyoshi Kosaka, Hiroaki Kanda, Takahiro Ochiya, Shingo Sato, Chihiro Akazawa
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Prostate cancer is one of most common cancers in men worldwide, and osteoblastic bone metastasis is frequently observed in prostate cancer patients. However, the mechanisms responsible for the predominantly osteoblastic phenotype have no