Zobrazeno 1 - 10
of 176
pro vyhledávání: '"Toru, Takeo"'
Autor:
Yuta Ishizuka, Satohiro Nakao, Tsutomu Kamisako, Katsuma Yamaga, Naomi Nakagata, Hiroyoshi Ishizaki, Toru Takeo
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract The cryopreservation of rat embryos is useful for efficiently archiving rat resources in bioresource repositories. The cryopreserved fertilized oocytes can be quickly reanimated to rats with homozygous mutations using embryo transfer. In add
Externí odkaz:
https://doaj.org/article/ed4839877c5a4a6281293419d5904b1f
Autor:
Lydia Teboul, James Amos-Landgraf, Fernando J. Benavides, Marie-Christine Birling, Steve D. M. Brown, Elizabeth Bryda, Rosie Bunton-Stasyshyn, Hsian-Jean Chin, Martina Crispo, Fabien Delerue, Michael Dobbie, Craig L. Franklin, Ernst-Martin Fuchtbauer, Xiang Gao, Christelle Golzio, Rebecca Haffner, Yann Hérault, Martin Hrabe de Angelis, Kevin C. Kent Lloyd, Terry R. Magnuson, Lluis Montoliu, Stephen A. Murray, Ki-Hoan Nam, Lauryl M. J. Nutter, Eric Pailhoux, Fernando Pardo Manuel de Villena, Kevin Peterson, Laura Reinholdt, Radislav Sedlacek, Je Kyung Seong, Toshihiko Shiroishi, Cynthia Smith, Toru Takeo, Louise Tinsley, Jean-Luc Vilotte, Søren Warming, Sara Wells, C. Bruce Whitelaw, Atsushi Yoshiki, Asian Mouse Mutagenesis Resource Association, CELPHEDIA infrastructure, INFRAFRONTIER consortium, International Mammalian Genome Society, International Mouse Phenotyping Consortium, International Society for Transgenic Technologies, Mutant Mouse Resource and Research Centers, Phenomics Australia, RRRC- Rat Resource and Research Center, Guillaume Pavlovic
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-8 (2024)
Abstract The biomedical research community addresses reproducibility challenges in animal studies through standardized nomenclature, improved experimental design, transparent reporting, data sharing, and centralized repositories. The ARRIVE guideline
Externí odkaz:
https://doaj.org/article/81e4d92fe0424d7c9017a0c563ae6724
Autor:
Risa Sakamoto, Takuji Fujiwara, Yuko Kawano, Shizu Aikawa, Tomoaki Inazumi, On Nakayama, Yukiko Kawasaki-Shirata, Miho Hashimoto-Iwasaki, Toshiko Sugimoto, Soken Tsuchiya, Satohiro Nakao, Toru Takeo, Yasushi Hirota, Yukihiko Sugimoto
Publikováno v:
Journal of Lipid Research, Vol 65, Iss 10, Pp 100636- (2024)
To investigate the yet-unknown roles of prostaglandins (PGs) in the uterus, we analyzed the expression of various PG receptors in the uterus. We found that three types of Gs-coupled PG receptors, DP, EP2, and EP4, were expressed in luminal epithelial
Externí odkaz:
https://doaj.org/article/4348ced3604448f3a4a4d76898ea9b70
Autor:
Rahmawati Aisyah, Noriyasu Ohshima, Daiki Watanabe, Yoshiko Nakagawa, Tetsushi Sakuma, Felix Nitschke, Minako Nakamura, Koji Sato, Kaori Nakahata, Chihiro Yokoyama, Charlotte R. Marchioni, Thanutchaporn Kumrungsee, Takahiko Shimizu, Yusuke Sotomaru, Toru Takeo, Naomi Nakagata, Takashi Izumi, Shinji Miura, Berge A. Minassian, Takashi Yamamoto, Masanobu Wada, Noriyuki Yanaka
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-17 (2024)
Abstract Glycerophosphocholine (GPC) is an important precursor for intracellular choline supply in phosphatidylcholine (PC) metabolism. GDE5/Gpcpd1 hydrolyzes GPC into choline and glycerol 3-phosphate; this study aimed to elucidate its physiological
Externí odkaz:
https://doaj.org/article/cb2483d665d74748b78e1920755b6628
Autor:
Katsuma YAMAGA, Satohiro NAKAO, Nobuyuki MIKODA, Jorge Mario SZTEIN, Naomi NAKAGATA, Toru TAKEO
Publikováno v:
The Journal of Reproduction and Development, Vol 70, Iss 2, Pp 131-137 (2024)
Cold transport of the cauda epididymides is a useful technique for shipping laboratory rat sperm. Cold transport of rat sperm avoids potential risks of microbiological infection, animal escape or death, and animal welfare issues. Previously, we repor
Externí odkaz:
https://doaj.org/article/45abf663ee8648a78d934ba8b1618e99
Publikováno v:
The Journal of Reproduction and Development, Vol 70, Iss 2, Pp 123-130 (2024)
Genetically modified rats are valuable models in human disease research. We recently developed an improved system for rat sperm cryopreservation and in vitro fertilization (IVF) that facilitates the efficient production and preservation of geneticall
Externí odkaz:
https://doaj.org/article/b035477e0d91437eb1856a4064ad4a07
Autor:
Yusei Yamada, Madoka Fukaura‐Nishizawa, Asami Nishiyama, Akira Ishii, Tatsuya Kawata, Aina Shirakawa, Mayuko Tanaka, Yuki Kondo, Toru Takeo, Naomi Nakagata, Toru Miwa, Hiroki Takeda, Yorihisa Orita, Keiichi Motoyama, Taishi Higashi, Hidetoshi Arima, Takahiro Seki, Yuki Kurauchi, Hiroshi Katsuki, Katsumi Higaki, Kentaro Minami, Naoki Yoshikawa, Ryuji Ikeda, Muneaki Matsuo, Tetsumi Irie, Yoichi Ishitsuka
Publikováno v:
Clinical and Translational Medicine, Vol 13, Iss 8, Pp n/a-n/a (2023)
Abstract Background Niemann–Pick disease type C (NPC) is a fatal neurodegenerative disorder caused by abnormal intracellular cholesterol trafficking. Cyclodextrins (CDs), the most promising therapeutic candidates for NPC, but with concerns about ot
Externí odkaz:
https://doaj.org/article/4e90738b28c44e4c9ddaf53a1c5805b3
Autor:
Satohiro Nakao, Kotono Ito, Chihiro Sugahara, Hitomi Watanabe, Gen Kondoh, Naomi Nakagata, Toru Takeo
Publikováno v:
PLoS ONE, Vol 18, Iss 2, p e0281330 (2023)
The number of sperm that reaches the oocytes in mammalian species is limited. In mice, 8-10 oocytes are ovulated, a similar number of sperm reaches the oocytes, and nearly all oocytes are fertilized via natural mating. Meanwhile, our improved superov
Externí odkaz:
https://doaj.org/article/f9318075d01941a88ebea707ed0c06be
Quercetin-treated rat sperm enables refrigerated transport with motility and fertility for five days
Autor:
Katsuma Yamaga, Satohiro Nakao, Nobuyuki Mikoda, Hidetaka Yoshimoto, Ena Nakatsukasa, Naomi Nakagata, Toru Takeo
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Shipment of laboratory rats between animal facilities is frequently performed using special containers. However, the shipment of live animals is associated with potential risks of infectious diseases, escape and death during shipment and ani
Externí odkaz:
https://doaj.org/article/d9562981f159469689a0ae9bc2299f33
Autor:
Hiroshi Watanabe, Rui Fujimura, Yuto Hiramoto, Ryota Murata, Kento Nishida, Jing Bi, Tadashi Imafuku, Hisakazu Komori, Hitoshi Maeda, Ayumi Mukunoki, Toru Takeo, Naomi Nakagata, Motoko Tanaka, Kazutaka Matsushita, Masafumi Fukagawa, Toru Maruyama
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract The molecular mechanism for acute kidney injury (AKI) and its progression to chronic kidney disease (CKD) continues to be unclear. In this study, we investigated the pathophysiological role of the acute phase protein α1-acid glycoprotein (A
Externí odkaz:
https://doaj.org/article/39863770c8144052b17dfd1f72939b0f