Výsledky vyhledávání - "Toru, Hiraga"

Akademický článek

Osteogenic Factor Runx2 Marks a Subset of Leptin Receptor-Positive Cells that Sit Atop the Bone Marrow Stromal Cell Hierarchy

Autor: Mengyu Yang, Atsushi Arai, Nobuyuki Udagawa, Toru Hiraga, Zhao Lijuan, Susumu Ito, Toshihisa Komori, Takeshi Moriishi, Koichi Matsuo, Kouji Shimoda, Ali H. Zahalka, Yasuhiro Kobayashi, Naoyuki Takahashi, Toshihide Mizoguchi

Publikováno v: Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)

Abstract Bone marrow mesenchymal stem and progenitor cells (BM-MSPCs) maintain homeostasis of bone tissue by providing osteoblasts. Although several markers have been identified for labeling of MSPCs, these labeled cells still contain non-BM-MSPC pop

Externí odkaz: https://doaj.org/article/cadaaf04dcdd4fafb0cada7bb88b1263

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Data from Opposing Effects of Granulocyte Colony-Stimulating Factor on the Initiation and Progression of Breast Cancer Bone Metastases

Autor: Toshihide Mizoguchi, Susumu Ito, Toru Hiraga

Granulocyte colony stimulating factor (G-CSF), an essential cytokine regulating granulopoiesis, is expressed in a substantial proportion of breast cancers, and it has been implicated in cancer progression. Here, we examined effects of G-CSF on the de

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1711019cbff224e34a3687f2394a8379
https://doi.org/10.1158/1541-7786.c.6544962

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Supplementary Figures from Cancer Stem–like Cell Marker CD44 Promotes Bone Metastases by Enhancing Tumorigenicity, Cell Motility, and Hyaluronan Production

Autor: Hiroaki Nakamura, Susumu Ito, Toru Hiraga

Supplementary Figures - PDF file 1473K, Supplementary Figure S1 Flow cytometric analysis of CD44 expression in the human cancer cell lines, MDA-MB-231 (A, breast cancer), A375 (B, melanoma), PC-3 (C, prostate cancer), HARA-B (D, lung cancer), and MCF

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08570ad7f369b054b48fe9b59b30c1ad
https://doi.org/10.1158/0008-5472.22396586.v1

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Supplementary Figure 1 from Bone-Derived IGF Mediates Crosstalk between Bone and Breast Cancer Cells in Bony Metastases

Autor: Toshiyuki Yoneda, Gregory R. Mundy, Clifford J. Rosen, Hideki Yoshikawa, Yoshihiro Morita, Kenji Hata, Akira Sasaki, Nobuyuki Hashimoto, Akira Myoui, Toru Hiraga

PDF file - 172K, Effects of IGFIR knockdown in MDA-MB-231 cells on bone metastases. This figure shows the results of the experiments in which the effects of IGFIR knock-down in MDA-MB-231 cells using shRNA on bne metastasis were examined.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09e55d513f246f23693d8271fade3063
https://doi.org/10.1158/0008-5472.22392215

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Data from Cancer Stem–like Cell Marker CD44 Promotes Bone Metastases by Enhancing Tumorigenicity, Cell Motility, and Hyaluronan Production

Autor: Hiroaki Nakamura, Susumu Ito, Toru Hiraga

CD44, an adhesion molecule that binds to the extracellular matrix, primarily to hyaluronan (HA), has been implicated in cancer cell migration, invasion, and metastasis. CD44 has also recently been recognized as a marker for stem cells of several type

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69dd0af19d30741547a408844ca11f68
https://doi.org/10.1158/0008-5472.c.6504611

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