Zobrazeno 1 - 10
of 460
pro vyhledávání: '"Torsten Witte"'
Autor:
Konstantin Fritz Jendretzky, Lisa-Marie Lezius, Thea Thiele, Franz Felix Konen, André Huss, Lena Heitmann, Yunus Emre Güzeloglu, Philipp Schwenkenbecher, Kurt-Wolfram Sühs, Jelena Skuljec, Mike Peter Wattjes, Torsten Witte, Christoph Kleinschnitz, Refik Pul, Hayrettin Tumani, Stefan Gingele, Thomas Skripuletz
Publikováno v:
Neurological Research and Practice, Vol 6, Iss 1, Pp 1-10 (2024)
Abstract Background Diagnosing multiple sclerosis (MS) is challenging due to diverse symptoms and the absence of specific biomarkers. Concurrent autoimmune diseases (AID) or non-specific antibodies further complicate diagnosis, progression monitoring
Externí odkaz:
https://doaj.org/article/8e185e916ca14246bf45240d22f85721
Autor:
Peter C. Taylor, Alejandro Balsa, Anne-Barbara Mongey, Mária Filková, Myriam Chebbah, Solenn Le Clanche, Linda A. W. Verhagen, Torsten Witte, Daniela Opris-Belinski, Hubert Marotte, Jérôme Avouac
Publikováno v:
Rheumatology and Therapy, Vol 11, Iss 6, Pp 1425-1435 (2024)
Abstract This commentary explores the potential cardiovascular (CV) benefits of combining methotrexate (MTX) and Janus kinase inhibitors (JAKis) in the treatment of rheumatoid arthritis (RA). While European guidelines recommend MTX as first-line trea
Externí odkaz:
https://doaj.org/article/c93fce690cd94334afbf1764694f45ad
Autor:
Melanie Haar, Franz Felix Konen, Marten A. Gehlhaar, Irene Oluwatoba-Popoola, Emilia Donicova, Marija Wachsmann, Ahmed Lubbad, Katerina Hufendiek, Amelie Pielen, Bettina Hohberger, Christian Mardin, Stefan Gingele, Nils K. Prenzler, Diana Ernst, Torsten Witte, Carsten Framme, Thomas Skripuletz, Tabea Seeliger, Anna Bajor
Publikováno v:
Therapeutic Advances in Ophthalmology, Vol 16 (2024)
Background: Sjögren’s syndrome is an autoimmune disease characterized by sicca symptoms and various extraglandular manifestations including vasculitis. Neurological involvement occurs frequently (Neuro-Sjögren) and often mimics immune neuropathie
Externí odkaz:
https://doaj.org/article/5b53532b8dff45019cd72bca4d35264e
Autor:
Torsten Witte, Thomas Thum, Diana Ernst, Nadine Zehrfeld, Malin Abelmann, Sabrina Benz, Tabea Seeliger, Thomas Skripuletz, Anselm Arthur Derda, Kristina Sonnenschein, Fiona Engelke, Christian Baer
Publikováno v:
RMD Open, Vol 10, Iss 3 (2024)
Background MicroRNAs (miRNAs) can regulate gene expression, controlling numerous cellular processes. Dysregulation of miRNA function is linked to various diseases, making them attractive diagnostic and therapeutic targets. Examples include hsa-miR-92
Externí odkaz:
https://doaj.org/article/3b0f6a42d79d455e86ca3629e831d18b
Autor:
Faranaz Atschekzei, Stephan Traidl, Julia Carlens, Katharina Schütz, Sandra von Hardenberg, Abdulwahab Elsayed, Diana Ernst, Linus Risser, Thea Thiele, Theresa Graalmann, Juliana Raab, Ulrich Baumann, Torsten Witte, Georgios Sogkas
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
ObjectiveThe signal transducer and activator of transcription 3 (STAT3) gain-of-function (GOF) syndrome (STAT3-GOF) is an inborn error of immunity (IEI) characterized by diverse manifestations of immune dysregulation that necessitate systemic immunom
Externí odkaz:
https://doaj.org/article/ec35e62e95e345bda9ae17fda9dc6942
Autor:
Patrick-Pascal Strunz, Linus Maximilian Risser, Matthias Englbrecht, Torsten Witte, Matthias Froehlich, Marc Schmalzing, Michael Gernert, Sebastian Hueper, Peter Bartz-Bazzanella, Cay von der Decken, Kirsten Karberg, Georg Gauler, Susanna Späthling-Mestekemper, Christoph Kuhn, Wolfgang Vorbrüggen, Martin Welcker, Stefan Kleinert
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundSafety recommendations for Janus kinase inhibitors (JAKi) issued by the European Medical Agency (EMA) in 2023 could potentially influence treatment patterns for rheumatoid arthritis (RA) drugs, but little is known about the impact of these
Externí odkaz:
https://doaj.org/article/8fdf039605db47819e20145e68fee00c
Autor:
Patrick-Pascal Strunz, Matthias Englbrecht, Linus Maximilian Risser, Torsten Witte, Matthias Froehlich, Marc Schmalzing, Michael Gernert, Astrid Schmieder, Peter Bartz-Bazzanella, Cay von der Decken, Kirsten Karberg, Georg Gauler, Patrick Wurth, Susanna Späthling-Mestekemper, Christoph Kuhn, Wolfgang Vorbrüggen, Johannes Heck, Martin Welcker, Stefan Kleinert
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
ObjectiveTreatment options with disease-modifying antirheumatic drugs (DMARDs) for psoriatic arthritis (PsA) have evolved over recent years. In addition to Janus kinase inhibitors (JAKi), four classes of biologic DMARDs (bDMARDs; interleukin [IL]-23
Externí odkaz:
https://doaj.org/article/d38dc92500c142f5b13b040faad3b569
Autor:
Torsten Witte, Georgios Sogkas, Diana Ernst, Nadine Zehrfeld, Malin Abelmann, Sabrina Benz, Clara Luisa Zippel, Sonja Beider, Emelie Kramer, Tabea Seeliger, Vega Gödecke, Gerrit Ahrenstorf, Franz Paul Armbruster, Thomas Skripuletz, Anselm Arthur Derda, Kristina Sonnenschein
Publikováno v:
RMD Open, Vol 10, Iss 2 (2024)
Objectives Cardiovascular comorbidities are common in patients with autoimmune diseases. This study investigates the extent of subclinical atherosclerosis in patients with primary Sjögren’s syndrome (pSS). Correlations with clinical factors such a
Externí odkaz:
https://doaj.org/article/7cba1e0f41c947f99cbc53480ff0f688
Publikováno v:
Lupus Science and Medicine, Vol 11, Iss Suppl 1 (2024)
Externí odkaz:
https://doaj.org/article/0fca1f2efdaa4ce2b0574acde15904dd
Autor:
Julius Lindblom, Lorenzo Beretta, Maria Orietta Borghi, PRECISESADS Clinical Consortium, Marta E. Alarcón-Riquelme, Ioannis Parodis, Barbara Vigone, Jacques-Olivier Pers, Alain Saraux, Valérie Devauchelle-Pensec, Divi Cornec, Sandrine Jousse-Joulin, Bernard Lauwerys, Julie Ducreux, Anne-Lise Maudoux, Carlos Vasconcelos, Ana Tavares, Esmeralda Neves, Raquel Faria, Mariana Brandão, Ana Campar, António Marinho, Farinha Fátima, Isabel Almeida, Angel Gonzalez-Gay Mantecón, Ricardo Blanco Alonso, Alfonso Corrales Martínez, Ricard Cervera, Ignasi Rodríguez-Pintó, Gerard Espinosa, Rik Lories, Ellen De Langhe, Nicolas Hunzelmann, Doreen Belz, Torsten Witte, Niklas Baerlecken, Georg Stummvoll, Michael Zauner, Michaela Lehner, Eduardo Collantes, Rafaela Ortega-Castro, MaAngeles Aguirre-Zamorano, Alejandro Escudero-Contreras, MaCarmen Castro-Villegas, Norberto Ortego, María Concepción Fernández Roldán, Enrique Raya, Inmaculada Jiménez Moleón, Enrique de Ramon, Isabel Díaz Quintero, Pier Luigi Meroni, Maria Gerosa, Tommaso Schioppo, Carolina Artusi, Carlo Chizzolini, Aleksandra Zuber, Donatienne Wynar, Laszló Kovács, Attila Balog, Magdolna Deák, Márta Bocskai, Sonja Dulic, Gabriella Kádár, Falk Hiepe, Velia Gerl, Silvia Thiel, Manuel Rodriguez Maresca, Antonio López-Berrio, Rocío Aguilar-Quesada, Héctor Navarro-Linares.
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionSystemic lupus erythematosus (SLE) is a clinically heterogeneous disease that presents a challenge for clinicians. To identify potential biomarkers for diagnosis and disease activity in SLE, we investigated a selected yet broad panel of c
Externí odkaz:
https://doaj.org/article/fa86e3d0c5a440e99c263f4433d82b5a