As Verified with the Aid of Biotinylated Spermine, the Brain Cannot Take up Polyamines from the Bloodstream Leaving It Solely Dependent on Local Biosynthesis

Autor: Torsten Weiss, René Bernard, Gregor Laube, Julian Rieck, Misty J. Eaton, Serguei N. Skatchkov, Rüdiger W. Veh

Publikováno v: Biomolecules, Vol 13, Iss 7, p 1114 (2023)

The importance of polyamines (PAs) for the central nervous system (CNS) is well known. Less clear, however, is where PAs in the brain are derived from. Principally, there are three possibilities: (i) intake by nutrition, release into the bloodstream,

Externí odkaz: https://doaj.org/article/6f0b1506cfe547f4ab22e9a32afb4327

The Brain Cannot Take Up Polyamines from the Blood Stream Leaving It Solely Dependent on Local Biosynthesis As Demonstrated Here with the Aid of Biotinylated Spermine

Autor: Torsten Weiss, René Bernard, Gregor Laube, Julian Rieck, Misty Eaton, Serguei N Skatchkov, Rüdiger W. Veh

The importance of PAs for CNS functions are well known. Less clear is, however, where PAs in the brain are derived from. Principally, there are three possibilities: (i) intake by nutrition, release into the bloodstream, and subsequent uptake from CNS

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1cecaaa382a85f44eb505fd33b1f6a3b
https://doi.org/10.20944/preprints202305.1643.v1

A Novel Giant Non-Cholinergic Striatal Interneuron Restricted to the Ventrolateral Striatum Coexpresses Kv3.3 Potassium Channel, Parvalbumin, and the Vesicular GABA Transporter

Autor: Daniel S. Zahm, Lydia Lebenheim, Sam A. Booker, Rüdiger W. Veh, Imre Vida, Torsten Weiss, Franziska Wagner, Clemens Gruber, Christian Derst

Publikováno v: Lebenheim, L, Booker, S, Derst, C, Weiss, T, Wagner, F, Gruber, C, Vida, I, Zahm, D S & Veh, R W 2020, ' A Novel Giant Non-Cholinergic Striatal Interneuron Restricted to the Ventrolateral Striatum Coexpresses Kv3.3 Potassium Channel, Parvalbumin, and the Vesicular GABA Transporter ', Molecular Psychiatry, vol. N/A, pp. 1-14 . https://doi.org/10.1038/s41380-020-00948-4

The striatum is the main input structure of the basal ganglia. Distinct striatal subfields are involved in voluntary movement generation and cognitive and emotional tasks, but little is known about the morphological and molecular differences of stria

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc614e5aeb04a9416ae3af8247f8ab91
https://www.pure.ed.ac.uk/ws/files/186571951/s41380_020_00948_4.pdf

Manipulating Aggregation Behavior of the Uncharged Peptide Carbetocin

Autor: Torsten Weiss, Jesper Østergaard, Ulrich B. Høgstedt, Helen Ulrika Sjögren, Marco van de Weert

Publikováno v: Journal of pharmaceutical sciences. 107(3)

Peptides are usually administered through subcutaneous injection. For low potency drugs, this may require high concentration formulations increasing the risk of peptide aggregation, especially for compounds without any intrinsic chargeable groups. Ca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcef290515f5c33ebfc350a554231e3c
https://pubmed.ncbi.nlm.nih.gov/29162423

B. Schutzzwecke des Gläubigerschutzssystems im GmbH-Recht – Richtwert und Grenzen der Auslegung

Autor: André Torsten Weiß

Publikováno v: Insolvenzspezifische Geschäftsführerhaftung: Zahlungsverbote, Existenzvernichtung und Insolvenzverschleppung

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0a65e96095cfec3fa9db724998c5a7d4
https://doi.org/10.15375/9783814557892-004