Zobrazeno 1 - 10
of 229
pro vyhledávání: '"Torsten Tonn"'
Autor:
Torsten Tonn, Hans Klingemann, Winfried S Wels, Jiri Eitler, Natalie Wotschel, Laurent Boissel, Michael Bachmann, Wiebke Rackwitz, Venugopal Gudipati, Nivedha Murali Shankar, Anastasia Sidorenkova, Johannes B Huppa, Paola Ortiz-Montero, Corinna Opitz, Stephan R Künzel, Susanne Michen, Achim Temme, Liliana Rodrigues Loureiro, Anja Feldmann
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 2 (2024)
Background The antitumor activity of natural killer (NK) cells can be enhanced by specific targeting with therapeutic antibodies that trigger antibody-dependent cell-mediated cytotoxicity (ADCC) or by genetic engineering to express chimeric antigen r
Externí odkaz:
https://doaj.org/article/635e8a9c7ed146e6934cedabb216012a
Autor:
David Digomann, Max Heiduk, Charlotte Reiche, Jessica Glück, Christoph Kahlert, Peter Mirtschink, Anna Klimova, Florian Bösch, Torsten Tonn, Jochen Gaedcke, Michael Ghadimi, Jürgen Weitz, Lena Seifert, Adrian M. Seifert
Publikováno v:
npj Precision Oncology, Vol 7, Iss 1, Pp 1-9 (2023)
Abstract Pancreatic ductal adenocarcinoma (PDAC) responds poorly to systemic treatment, including new immunotherapeutic approaches. Biomarkers are urgently needed for early disease detection, patient stratification for treatment, and response predict
Externí odkaz:
https://doaj.org/article/c19f5bd9248f4e8393bbb8bdfd097f13
Autor:
Torsten Tonn, Winfried Wels, Hans Klingemann, Jiri Eitler, Natalie Wotschel, Laurent Boissel, Paola Ortiz Montero, Wiebke Rackwitz, Venugopal Gudipati, Johannes Huppa
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 2 (2023)
Externí odkaz:
https://doaj.org/article/6631a9096b6341f49cfecf75a7de5933
Autor:
Nivedha Murali Shankar, Paola Ortiz-Montero, Anastasia Kurzyukova, Wiebke Rackwitz, Stephan R. Künzel, Winfried S. Wels, Torsten Tonn, Franziska Knopf, Jiri Eitler
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Natural killer (NK) cells are attractive effectors for adoptive immunotherapy of cancer. Results from first-in-human studies using chimeric antigen receptor (CAR)-engineered primary NK cells and NK-92 cells are encouraging in terms of efficacy and sa
Externí odkaz:
https://doaj.org/article/ffb0dee5b8bf4f79b3022bb7448c7718
Autor:
Renata Nacasaki Silvestre, Jiri Eitler, Julia Teixeira Cottas de Azevedo, Mariane Cariati Tirapelle, Daianne Maciely Carvalho Fantacini, Lucas Eduardo Botelho de Souza, Kamilla Swiech, Dimas Tadeu Covas, Rodrigo T. Calado, Paola Ortiz Montero, Kelen Cristina Ribeiro Malmegrim, Marxa L. Figueiredo, Torsten Tonn, Virginia Picanço-Castro
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionNatural killer 92 (NK-92) cells are an attractive therapeutic approach as alternative chimeric antigen receptor (CAR) carriers, different from T cells, once they can be used in the allogeneic setting. The modest in vivo outcomes observed
Externí odkaz:
https://doaj.org/article/3c70f6d73d3641458e2db201ea935271
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/d8b7de852b594bc3bc03212857ac4eae
Autor:
Catrin Heim, Laura M. Moser, Herman Kreyenberg, Halvard B. Bonig, Torsten Tonn, Winfried S. Wels, Elise Gradhand, Evelyn Ullrich, Michael T. Meister, Marian Groot Koerkamp, Frank C. P. Holstege, Jarno Drost, Jan-Henning Klusmann, Peter Bader, Michael Merker, Eva Rettinger
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionMetastatic rhabdomyosarcoma (RMS) is a challenging tumor entity that evades conventional treatments and endogenous antitumor immune responses, highlighting the need for novel therapeutic strategies. Applying chimeric antigen receptor (CAR
Externí odkaz:
https://doaj.org/article/a67ec3b12510448385698d63f9fbce7d
Autor:
Miriam N. Jacobs, Jan M. Bult, Kevin Cavanagh, Christophe Chesne, Nathalie Delrue, Jianan Fu, Emma Grange, Ingrid Langezaal, Dominika Misztela, Jenny Murray, Martin Paparella, Gilly Stoddart, Torsten Tonn, Carol Treasure, Masaaki Tsukano, Rosemary Versteegen
Publikováno v:
Frontiers in Toxicology, Vol 5 (2023)
The ethical needs and concerns with use and sourcing of human materials, particularly serum, in OECD in vitro test guidelines were explored in a dedicated international workshop held in 2019. The health-related aspects of the donation procedure, incl
Externí odkaz:
https://doaj.org/article/64e648c9e6894018be64557ad5a4ea22
Autor:
Claudia Arndt, Antje Tunger, Rebekka Wehner, Rebecca Rothe, Eleni Kourtellari, Stephanie Luttosch, Katharina Hannemann, Stefanie Koristka, Liliana R. Loureiro, Anja Feldmann, Torsten Tonn, Theresa Link, Jan Dominik Kuhlmann, Pauline Wimberger, Michael Philipp Bachmann, Marc Schmitz
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
The cyclin-dependent kinase 4 and 6 (CDK4/6) inhibitor palbociclib is an emerging cancer therapeutic that just recently gained Food and Drug Administration approval for treatment of estrogen receptor (ER)-positive, human epidermal growth factor recep
Externí odkaz:
https://doaj.org/article/d050e2b4207a49ff823ba99d4383286d
Autor:
Stefan Ludwig, Marius Distler, Undine Schubert, Janine Schmid, Henriette Thies, Thilo Welsch, Sebastian Hempel, Torsten Tonn, Jürgen Weitz, Stefan R. Bornstein, Barbara Ludwig
Publikováno v:
Communications Medicine, Vol 2, Iss 1, Pp 1-7 (2022)
Ludwig and Distler et al. evaluate quality of life and metabolic outcomes in patients undergoing total pancreatectomy and simultaneous islet autotransplantation. The authors report benefits in terms of glycemic control, as well as improvements in qua
Externí odkaz:
https://doaj.org/article/0ea4df2a5a104cc899b4a7e98295f88e