Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Torsten Schultz-Fademrecht"'
Autor:
Luisa Stroppel, Torsten Schultz-Fademrecht, Martin Cebulla, Michaela Blech, Richard J. Marhöfer, Paul M. Selzer, Patrick Garidel
Publikováno v:
Pharmaceutics, Vol 15, Iss 2, p 563 (2023)
Biological drugs intended for multi-dose application require the presence of antimicrobial preservatives to avoid microbial growth. As the presence of certain preservatives has been reported to increase protein and peptide particle formation, it is e
Externí odkaz:
https://doaj.org/article/8d498e215cc642b898229db9c9c84504
Publikováno v:
International journal of pharmaceutics. 604
The present study investigated the photodegradation of three different monoclonal antibodies (mAb) by visible light. Several chromatographic techniques, such as size-exclusion and hydrophobic interaction chromatography as well as mass spectrometry we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa10f97a5511afc43dbe0c26c1020de9
https://pubmed.ncbi.nlm.nih.gov/34022254
https://pubmed.ncbi.nlm.nih.gov/34022254
Publikováno v:
Journal of Chromatography B. 1157:122287
Polysorbates are widely used as non-ionic surfactant in biopharmaceutical formulations. Recently, the degradation of polysorbate moved into the focus of attention, because in several published studies it was described, that stability issues in polyso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15b54e8e2f844c2907ce2d210d6ba845
https://doi.org/10.1016/j.jchromb.2020.122287
https://doi.org/10.1016/j.jchromb.2020.122287
Autor:
Klaus-Jurgen Steffens, Karoline Bechtold-Peters, Corinna König, Torsten Schultz-Fademrecht, Stefan Bassarab, Verena Baum
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 80:490-498
A novel protein-coated microcrystal (PCMC) technology offers the possibility to produce dry protein formulations suitable for inhalation or, after reconstitution, for injection. Micron-sized particles are hereby produced by co-precipitation via a rap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdf70440d650c4611d408c430a6b3577
https://doi.org/10.1016/j.ejpb.2011.11.012
https://doi.org/10.1016/j.ejpb.2011.11.012
Autor:
Patrick Garidel, Wolfgang Friess, Silke Muehlau, Virginie Le Brun, Torsten Schultz-Fademrecht
Publikováno v:
Biotechnology journal. 4(9)
The purpose of the presented study is to understand the physicochemical properties of proteins in aqueous solutions in order to identify solution conditions with reduced attractive protein-protein interactions, to avoid the formation of protein aggre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e911a4ab94453c359eb1a7056ce38309
https://pubmed.ncbi.nlm.nih.gov/19579219
https://pubmed.ncbi.nlm.nih.gov/19579219