Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Torsten Schmenger"'
Publikováno v:
npj Genomic Medicine, Vol 7, Iss 1, Pp 1-7 (2022)
Abstract The rapid pace with which genetic variants are now being determined means there is a pressing need to understand how they affect biological systems. Variants from healthy individuals have previously been used to study blood groups or HLA div
Externí odkaz:
https://doaj.org/article/9b82b8d87ba74976ab3c362aa06c3118
Autor:
Samantha Ebersoll, Blessing Musunda, Torsten Schmenger, Natalie Dirdjaja, Mariana Bonilla, Bruno Manta, Kathrin Ulrich, Marcelo A. Comini, R. Luise Krauth-Siegel
Publikováno v:
Redox Biology, Vol 15, Iss C, Pp 532-547 (2018)
Trypanosoma brucei glutaredoxin 2 (Grx2) is a dithiol glutaredoxin that is specifically located in the mitochondrial intermembrane space. Bloodstream form parasites lacking Grx2 or both, Grx2 and the cytosolic Grx1, are viable in vitro and infectious
Externí odkaz:
https://doaj.org/article/176cb0454d8b4eb881f0d4a9dc67609f
Autor:
Dieter Lemke, Wolfgang Wick, Harald Fricke, Michael Platten, Michael Kluge, Martin Bendszus, Claudia Kunz, Christian Gieffers, Jürgen Debus, Amir Abdollahi, Uwe Haberkorn, Manfred Jugold, Christian Merz, Benedikt Wiestler, Andreas von Deimling, Jaromir Sykora, Torsten Schmenger, Theresa Bunse, Antje Wick, Felix Sahm, Petra Rübmann, Philipp-Niclas Pfenning, Carina M. Thomé, Jonas Blaes
Supplementary Figure 1: Detection of asunercept/ APG101 in brains of treated mice. Supplementary Figure 2: qPCR for MMP2 (A) or MMP9 (B) and representative images of human microglia after 12 h treatment with vehicle (I), 20 µg/ml APG101 (II), 50 U/m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03dd0115f80e90f8b03640535eda7b58
https://doi.org/10.1158/1541-7786.22513288
https://doi.org/10.1158/1541-7786.22513288
Autor:
Andreas von Deimling, Claudia Kunz, Philipp Niclas Pfenning, Antje Wick, Torsten Schmenger, Jürgen Debus, Martin Bendszus, Jonas Blaes, Dieter Lemke, Petra Rübmann, Christian Merz, Theresa Bunse, Harald Fricke, Felix Sahm, Michael Platten, Uwe Haberkorn, Michael Kluge, Wolfgang Wick, Christian Gieffers, Benedikt Wiestler, Jaromir Sykora, Manfred Jugold, Amir Abdollahi, Carina M. Thome
Publikováno v:
Molecular Cancer Research. 16:767-776
CD95 (Fas/APO-1), a death receptor family member, activity has been linked to tumorigenicity in multiple cancers, including glioblastoma multiforme (GBM). A phase II clinical trial on relapsed glioblastoma patients demonstrated that targeted inhibiti
Autor:
Mariana Bonilla, Blessing Musunda, Kathrin Ulrich, Marcelo A. Comini, Bruno Manta, Natalie Dirdjaja, Samantha Ebersoll, R. Luise Krauth-Siegel, Torsten Schmenger
Publikováno v:
Redox Biology
Redox Biology, Vol 15, Iss C, Pp 532-547 (2018)
Redox Biology, Vol 15, Iss C, Pp 532-547 (2018)
Trypanosoma brucei glutaredoxin 2 (Grx2) is a dithiol glutaredoxin that is specifically located in the mitochondrial intermembrane space. Bloodstream form parasites lacking Grx2 or both, Grx2 and the cytosolic Grx1, are viable in vitro and infectious
Autor:
Erik Jung, Felix Sahm, Miriam Gömmel, Michael Platten, Sabine Heiland, Benedikt Wiestler, Wolfgang Wick, Peter Häring, Matthias Osswald, Ruifan Xie, Frank Winkler, Katrin Deumelandt, Felix T. Kurz, Torsten Schmenger, Andreas von Deimling, Gergely Solecki, Carina M. Thome, Jonas Blaes, Mustafa Syed, Oliver Heil, Sophie Weil, Peter E. Huber
Early and progressive colonization of the healthy brain is one hallmark of diffuse gliomas, including glioblastomas. We recently discovered ultralong (>10 to hundreds of microns) membrane protrusions [tumor microtubes (TMs)] extended by glioma cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::893795f1c0137c334d4e4b4ca260168c
https://europepmc.org/articles/PMC6705725/
https://europepmc.org/articles/PMC6705725/
Autor:
Olga Garaschuk, Kianush Karimian Jazi, Christian Steinhäuser, Oliver Griesbeck, Samuel Weiss, Sophie Weil, Matthias Preusser, Mostafa Jarahian, Gergely Solecki, Varun Venkataramani, Felix Sahm, Miriam Gömmel, Michael Platten, Erik Jung, Lulu Huang, Jonas Blaes, Sabine Heiland, Thomas Kuner, Andreas von Deimling, Dieter Lemke, Martin Pauli, Mustafa Syed, Anna S. Berghoff, Heinz Horstmann, Hai-Kun Liu, Damir Krunic, Peter Häring, Stefan Pusch, Peter E. Huber, Matthias Osswald, Felix T. Kurz, Torsten Schmenger, Miriam Ratliff, Wolfgang Wick, Verena Herl, Benedikt Wiestler, Yunxiang Liao, Hrvoje Miletic, Georgios Kalamakis, Frank Winkler
Publikováno v:
Nature. 528(7580)
Astrocytic brain tumours, including glioblastomas, are incurable neoplasms characterized by diffusely infiltrative growth. Here we show that many tumour cells in astrocytomas extend ultra-long membrane protrusions, and use these distinct tumour micro