Zobrazeno 1 - 10
of 756
pro vyhledávání: '"Torsten Pietsch"'
Autor:
Frank A. Giordano, Julian P. Layer, Sonia Leonardelli, Lea L. Friker, Roberta Turiello, Dillon Corvino, Thomas Zeyen, Christina Schaub, Wolf Müller, Elena Sperk, Leonard Christopher Schmeel, Katharina Sahm, Christoph Oster, Sied Kebir, Peter Hambsch, Torsten Pietsch, Sotirios Bisdas, Michael Platten, Martin Glas, Clemens Seidel, Ulrich Herrlinger, Michael Hölzel
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract The chemokine CXCL12 promotes glioblastoma (GBM) recurrence after radiotherapy (RT) by facilitating vasculogenesis. Here we report outcomes of the dose-escalation part of GLORIA (NCT04121455), a phase I/II trial combining RT and the CXCL12-n
Externí odkaz:
https://doaj.org/article/a461b70c215e421cabb2b9a14f5dfb4b
Publikováno v:
Beilstein Journal of Nanotechnology, Vol 15, Iss 1, Pp 360-366 (2024)
We present a novel method combining anodic aluminum oxide template synthesis and nanolithography to selectively deposit vertically patterned magnetic nanowires on a Si substrate. With this approach we fabricated three-dimensional nanowire-based spin
Externí odkaz:
https://doaj.org/article/74c83ffe3d1c4ed8b89da4233e37496b
Autor:
Azadeh Ebrahimi, Andreas Waha, Jens Schittenhelm, Georg Gohla, Martin U Schuhmann, Torsten Pietsch
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-6 (2024)
Abstract Methylation class “CNS tumor with BCOR/BCOR(L1)-fusion” was recently defined based on methylation profiling and tSNE analysis of a series of 21 neuroepithelial tumors with predominant presence of a BCOR fusion and/or characteristic CNV b
Externí odkaz:
https://doaj.org/article/92fcd0a00ff14cf69c66db510b0f1ecd
Autor:
Richard Weiten, Max Niemann, Eduard Below, Lea L. Friker, Damian J. Ralser, Marieta Toma, Glen Kristiansen, Oliver Hahn, Sabrina Zechel, Viktor Grünwald, Tobias Bald, Johannes Siewert, Torsten Pietsch, Manuel Ritter, Michael Hölzel, Markus Eckstein, Abdullah Alajati, Philipp Krausewitz, Niklas Klümper
Publikováno v:
Cancer Medicine, Vol 13, Iss 12, Pp n/a-n/a (2024)
Abstract Purpose Improved survival rates have been observed in castration‐resistant prostate cancer (CRPC) due to advancements in treatment options. However, individuals with brain metastases still have limited therapeutic options and an unfavorabl
Externí odkaz:
https://doaj.org/article/296319f737d046debd441f74e94d7c29
Autor:
Tibor Kelety, Ulrich‐Wilhelm Thomale, Daniela Kandels, Martin U. Schuhmann, Ahmed El Damaty, Jürgen Krauss, Michael C. Frühwald, Pablo Hernáiz Driever, Olaf Witt, Brigitte Bison, Monika Warmuth‐Metz, Torsten Pietsch, René Schmidt, Astrid K. Gnekow
Publikováno v:
Cancer Medicine, Vol 13, Iss 12, Pp n/a-n/a (2024)
Abstract Introduction Neurosurgery is considered the mainstay of treatment for pediatric low‐grade glioma (LGG); the extent of resection determines subsequent stratification in current treatment protocols. Yet, surgical radicality must be balanced
Externí odkaz:
https://doaj.org/article/9835247168374d5b92afc12d21e76d00
Autor:
Saif-Eldin Abedellatif, Racha Hosni, Andreas Waha, Gerrit H. Gielen, Mohammed Banat, Motaz Hamed, Erdem Güresir, Anne Fröhlich, Judith Sirokay, Anna-Lena Wulf, Glen Kristiansen, Torsten Pietsch, Hartmut Vatter, Michael Hölzel, Matthias Schneider, Marieta Ioana Toma
Publikováno v:
Pharmaceutics, Vol 16, Iss 8, p 1042 (2024)
Background and aims: Brain metastases are prevalent in the late stages of malignant melanoma. Multimodal therapy remains challenging. Patient-derived organoids (PDOs) represent a valuable pre-clinical model, faithfully recapitulating key aspects of t
Externí odkaz:
https://doaj.org/article/2d511cd06e74457096edb876a891c881
Autor:
Jonas E. Adolph, Gudrun Fleischhack, Sebastian Tschirner, Lydia Rink, Christine Dittes, Ruth Mikasch, Philipp Dammann, Martin Mynarek, Denise Obrecht-Sturm, Stefan Rutkowski, Brigitte Bison, Monika Warmuth-Metz, Torsten Pietsch, Stefan M. Pfister, Kristian W. Pajtler, Till Milde, Rolf-Dieter Kortmann, Stefan Dietzsch, Beate Timmermann, Stephan Tippelt
Publikováno v:
Cancers, Vol 16, Iss 11, p 1955 (2024)
Background: Radiotherapy (RT) involving craniospinal irradiation (CSI) is important in the initial treatment of medulloblastoma. At recurrence, the re-irradiation options are limited and associated with severe side-effects. Methods: For pre-irradiate
Externí odkaz:
https://doaj.org/article/d3d6022ebfb7498792ed00f29dae73d7
Autor:
Elizabeth Schepke, Maja Löfgren, Torsten Pietsch, Teresia Kling, Claes Nordborg, Thomas Olsson Bontell, Stefan Holm, Anders Öberg, Per Nyman, Marie Eliasson-Hofvander, Magnus Sabel, Birgitta Lannering, Helena Carén
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-11 (2023)
Abstract Background Molecular analyses have shown that tumours diagnosed as supratentorial primitive neuro-ectodermal tumours of the central nervous system (CNS-PNETs) in the past represent a heterogenous group of rare childhood tumours including hig
Externí odkaz:
https://doaj.org/article/7e189eae54f44ad29c3940924f6752ee
Autor:
Julia Beckhaus, Svenja Boekhoff, Katrin Scheinemann, Freimut H Schilling, Gudrun Fleischhack, Gerhard Binder, Brigitte Bison, Torsten Pietsch, Carsten Friedrich, Hermann L Müller
Publikováno v:
Endocrine Connections, Vol 12, Iss 12, Pp 1-11 (2023)
Background: Craniopharyngiomas (CPs) are rare embryonic tumors. Clinical presentation and outcome of patients perinatally diagnosed with congenital CP (cCP) are not clear and refer mainly to a few case reports in the literature. The aim of this study
Externí odkaz:
https://doaj.org/article/10df589f694243d0bdd2893c38ea7ce4
Autor:
Robin A. Pilz, Dariush Skowronek, Motaz Hamed, Anja Weise, Elisabeth Mangold, Alexander Radbruch, Torsten Pietsch, Ute Felbor, Matthias Rath
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Cerebral cavernous malformations are clusters of aberrant vessels that can lead to severe neurological complications. Pathogenic loss-of-function variants in the CCM1, CCM2, or CCM3 gene are associated with the autosomal dominant form of the disease.
Externí odkaz:
https://doaj.org/article/d6dc71592f62442ab581a55813dbcf9d