Zobrazeno 1 - 10 of 18 pro vyhledávání: '"Torsten Klockenbring"'
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Akademický článek
Heterologous protection against malaria by a simple chemoattenuated PfSPZ vaccine regimen in a randomized trial
Autor: Zita Sulyok, Rolf Fendel, Bianca Eder, Freia-Raphaella Lorenz, Natasha KC, Matthias Karnahl, Albert Lalremruata, The T. Nguyen, Jana Held, Folashade Almeine Cyntiche Adjadi, Torsten Klockenbring, Judith Flügge, Tamirat Gebru Woldearegai, Carlos Lamsfus Calle, Javier Ibáñez, Miriam Rodi, Diane Egger-Adam, Andrea Kreidenweiss, Carsten Köhler, Meral Esen, Mihály Sulyok, Anita Manoj, Thomas L. Richie, B. Kim Lee Sim, Stephen L. Hoffman, Benjamin Mordmüller, Peter G. Kremsner
Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
In this placebo-controlled trial, 10/13 malaria naïve subjects immunized with a simplified regimen of chemoattenuated P. falciparum sporozoites, PfSPZ-CVac, show sterile protection from heterologous malaria challenge. Immunization was well tolerated
Externí odkaz: https://doaj.org/article/de6161831021472293648f15342062a5
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2
Akademický článek
Isolation and light chain shuffling of a Plasmodium falciparum AMA1-specific human monoclonal antibody with growth inhibitory activity
Autor: Melanie Seidel-Greven, Otchere Addai-Mensah, Holger Spiegel, Gwladys Nina Chiegoua Dipah, Stefan Schmitz, Gudrun Breuer, Margaret Frempong, Andreas Reimann, Torsten Klockenbring, Rainer Fischer, Stefan Barth, Rolf Fendel
Publikováno v: Malaria Journal, Vol 20, Iss 1, Pp 1-20 (2021)
Abstract Background Plasmodium falciparum, the parasite causing malaria, affects populations in many endemic countries threatening mainly individuals with low malaria immunity, especially children. Despite the approval of the first malaria vaccine Mo
Externí odkaz: https://doaj.org/article/4ef67ba7a0174ef2bfb421a7ccc904ff
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3
Isolation and light chain shuffling of a Plasmodium falciparum AMA1-specific human monoclonal antibody with growth inhibitory activity
Autor: Rolf Fendel, Margaret T. Frempong, Gudrun Breuer, Stefan Schmitz, Torsten Klockenbring, Rainer Fischer, Stefan Barth, Gwladys Nina Chiegoua Dipah, Otchere Addai-Mensah, Holger Spiegel, Andreas Reimann, Melanie Seidel-Greven
Publikováno v: Malaria Journal
Malaria Journal, Vol 20, Iss 1, Pp 1-20 (2021)
Background Plasmodium falciparum, the parasite causing malaria, affects populations in many endemic countries threatening mainly individuals with low malaria immunity, especially children. Despite the approval of the first malaria vaccine Mosquirix
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88d3a12a66734631fe55f0fb815ee666
https://publica.fraunhofer.de/handle/publica/269180
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4
Characterization of new anti-IL-6 antibodies revealed high potency candidates for intracellular cytokine detection and specific targeting of IL-6 receptor binding sites
Autor: Stefan Barth, Jörn Engelbert Schmitz, Karinna Chouman, Markus Sack, Birgit Korioth-Schmitz, Torsten Klockenbring, Rainer Fischer, Anh Tuan Pham, Rolf Fendel
Publikováno v: European Cytokine Network. 29:59-72
Interleukin-6 (IL-6) expression and secretion, induced by inflammatory processes, stimulate the acute phase response cascade. The overexpression of IL-6 contributes to a variety of inflammatory diseases, e.g. rheumatoid arthritis, Castleman's disease
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72cd72dae73fbd63a6b73a8d3eeca169
https://doi.org/10.1684/ecn.2018.0409
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5
Molecular Targeting Therapy against EGFR Family in Breast Cancer: Progress and Future Potentials
Autor: Felix Zeppernick, Marcus Niebert, Stefan Gattenlöhner, Amaia Eleonora Maennling, Ahmad Fawzi Hussain, Torsten Klockenbring, Ivo Meinhold-Heerlein, Mehmet Kemal Tur
Publikováno v: Cancers
Cancers 11(12), 1826 (2019). doi:10.3390/cancers11121826 special issue: "Special Issue "Epidermal Growth Factor Receptor Signaling in Cancer" / Special Issue Editors: Dr. Paul J. Higgins, Guest Editor; Dr. Rohan Samarakoon, Guest Editor"
Cancers, Vol 11, Iss 12, p 1826 (2019)
Cancers 11(12), 1826 (2019). doi:10.3390/cancers11121826
Published by MDPI, Basel
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17f1a98f8831ef5f9c32c46e39d09800
https://pubmed.ncbi.nlm.nih.gov/31756933
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6
Simultaneous and Independent Dual Site-Specific Self-Labeling of Recombinant Antibodies
Autor: Stefano Di Fiore, K. Bräutigam, Carolin Wollschlaeger, Xiaojing Cong, Torsten Klockenbring, Felix Zeppernick, Elmar Stickeler, Stefan Barth, Ivo Meinhold-Heerlein, Ahmad Fawzi Hussain
Antibody-based diagnostic and therapeutic reagents armed with effector molecules such as dyes and drugs offer hope in the battle against cancer. Several site-specific conjugation methods have been developed to equip antibodies with such effector mole
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2eb714f81622c84c7d851dee6c730eac
https://publica.fraunhofer.de/handle/publica/260518
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9
Fast track antibody V-gene rescue, recombinant expression in plants and characterization of a PfMSP4-specific antibody
Autor: Rainer Fischer, Melanie de Almeida, Andreas Reimann, Alexander Boes, Torsten Klockenbring, Stefan Barth, Stephanie Kapelski, Holger Spiegel, Rolf Fendel
Publikováno v: Malaria Journal
Malaria journal 14(1), 50 (2015). doi:10.1186/s12936-015-0577-7
Malaria journal 14(1), 50 (2015). doi:10.1186/s12936-015-0577-7
Published by BioMed Central, London
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e025a4205bf3fdc32f522e248965bfe
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10
In contrast to specific B cells, human basophils are unaffected by the toxic activity of an allergen toxin due to lack of internalization of immunoglobulin E-bound allergen
Autor: Torsten Klockenbring, H. Haas, Michael Stöcker, Stefan Barth, Wolf-Meinhard Becker, M. Wodrich, Daniel Wicklein, Arnd Petersen, Michael Huhn
Publikováno v: Clinical Experimental Allergy. 36:531-542
Summary Background Specific immunotherapy is the only curative therapy for type I allergies and the alarming increase in allergy prevalence emphasizes the need for additional/alternative strategies for curative treatment. Allergen toxins (AT), fusion
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc70e3d3b3d18608d81287e9ed8816cf
https://doi.org/10.1111/j.1365-2222.2006.02461.x
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