Inference of causal networks from time-varying transcriptome data via sparse coding.

Autor: Kai Zhang, Ju Han, Torsten Groesser, Gerald Fontenay, Bahram Parvin

Publikováno v: PLoS ONE, Vol 7, Iss 8, p e42306 (2012)

Temporal analysis of genome-wide data can provide insights into the underlying mechanism of the biological processes in two ways. First, grouping the temporal data provides a richer, more robust representation of the underlying processes that are co-

Externí odkaz: https://doaj.org/article/6b4cf01c5c8d4d10852e8539b37e8fb9

Non-catalytic Roles for XPG with BRCA1 and BRCA2 in Homologous Recombination and Genome Stability

Autor: Jan H.J. Hoeijmakers, Priscilla K. Cooper, Brian Shih, Ann C. Parplys, Miaw Sheue Tsai, Torsten Groesser, Kelly S. Trego, Janice M. Pluth, Ayesu Hlaing, Michael R. Nelson, Weixing Zhao, Patrick Sung, Claudia Wiese, Albert R. Davalos, Björn Rydberg, Judith Campisi

Publikováno v: Trego, K S, Groesser, T, Davalos, A R, Parplys, A C, Zhao, W, Nelson, M R, Hlaing, A, Shih, B, Rydberg, B, Pluth, J M, Tsai, M-S, Hoeijmakers, J H J, Sung, P, Wiese, C, Campisi, J & Cooper, P K 2016, ' Non-catalytic Roles for XPG with BRCA1 and BRCA2 in Homologous Recombination and Genome Stability ', Molecular Cell, vol. 61, pp. 535–546 . https://doi.org/10.1016/j.molcel.2015.12.026
Molecular cell, vol 61, iss 4
Trego, KS; Groesser, T; Davalos, AR; Parplys, AC; Zhao, W; Nelson, MR; et al.(2016). Non-catalytic Roles for XPG with BRCA1 and BRCA2 in Homologous Recombination and Genome Stability. Molecular Cell, 61(4), 535-546. doi: 10.1016/j.molcel.2015.12.026. Lawrence Berkeley National Laboratory: Lawrence Berkeley National Laboratory. Retrieved from: http://www.escholarship.org/uc/item/2618t9h0
Molecular Cell, 61(4), 535-546. Cell Press

© 2016 Elsevier Inc. XPG is a structure-specific endonuclease required for nucleotide excision repair, and incision-defective XPG mutations cause the skin cancer-prone syndrome xeroderma pigmentosum. Truncating mutations instead cause the neurodevel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bcfec2d212a7de1b61ea0d9e00e48d8
https://doi.org/10.1016/j.molcel.2015.12.026

Cell colony counter called CoCoNut

Autor: Mikael Jensen, Pil M. Fredericia, Stefano Dallolio, Mattia Siragusa, Torsten Groesser

Publikováno v: Siragusa, M, Dall'Olio, S, Fredericia, P M, Jensen, M, Groesser, T & Montazeri Aliabadi, H (ed.) 2018, ' Cell colony counter called CoCoNut ', PLOS ONE, vol. 13, no. 11, e0205823 . https://doi.org/10.1371/journal.pone.0205823
PLoS ONE
PLoS ONE, Vol 13, Iss 11, p e0205823 (2018)

Clonogenic assays are powerful tools for testing cell reproductive death after biological damage caused by, for example, ionizing radiation. Traditionally, the methods require a cumbersome, slow and eye-straining manual counting of viable colonies un

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40eabe8df0563c314918f33700dd74f9
https://orbit.dtu.dk/en/publications/7dfcc74c-2170-4da8-bfaf-bc70b79dc5de

Multiscale iterative voting for differential analysis of stress response for 2D and 3D cell culture models

Autor: Qing Yang, Hang Chang, M. Helen Barcellos‐Hoff, Ju Han, Gerald V. Fontenay, Torsten Groesser, Bahram Parvin

Publikováno v: Journal of Microscopy. 241:315-326

Summary Three-dimensional (2D) cell culture models have emerged as the basis for improved cell systems biology. However, there is a gap in robust computational techniques for segmentation of these model systems that are imaged through confocal or dec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dbf8c2cc8da877a6c8955994974490ee
https://doi.org/10.1111/j.1365-2818.2010.03442.x

Quantification of the Dynamics of DNA Repair to Ionizing Radiation via Colocalization of 53BP1 and ɣH2AX

Autor: Ju Han, Janice M. Pluth, Hang Chang, Bahram Parvin, Gerald V. Fontenay, Torsten Groesser

Publikováno v: Computational Biology ISBN: 9783319237237

Cellular response to stress can be manifested and visualized by measuring induced DNA damage. However, cellular systems can repair the damage through a variety of DNA repair pathways. It is important to characterize the dynamics of DNA repair in a va

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c9509ba6f6757a7e4c9cdac289db31bc
https://doi.org/10.1007/978-3-319-23724-4_14