Expression of Connexin43 Stimulates Endothelial Angiogenesis Independently of Gap Junctional Communication In Vitro

Autor: Christoph Koepple, Zizi Zhou, Kjestine Schmidt, Lena Huber, Matthias Schulte, Torsten Gloe, Cor de Wit, Volker Jürgen Schmidt, Ulrich Kneser

Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 7400, p 7400 (2021)
Volume 22
Issue 14
Koepple, C, Zhou, Z, Huber, L, Schulte, M, Schmidt, K, Gloe, T, Kneser, U, Schmidt, V J & de Wit, C 2021, ' Expression of connexin43 stimulates endothelial angiogenesis independently of gap junctional communication in vitro ', International Journal of Molecular Sciences, vol. 22, no. 14, 7400 . https://doi.org/10.3390/ijms22147400

Connexins (Cx) form gap junctions (GJ) and allow for intercellular communication. However, these proteins also modulate gene expression, growth, and cell migration. The downregulation of Cx43 impairs endothelial cell migration and angiogenetic potent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cb003df25bb9f7da50eb56cdc6324e1
https://doi.org/10.3390/ijms22147400

Isolation and functional characterization of pericytes derived from hamster skeletal muscle

Autor: Wolfram Nagel, B. Bergner, Petra Kameritsch, Ulrich Pohl, S. Wallner, Christina Mogensen, Torsten Gloe, V. Ninichuk, Angela Ritter, S. d’Avis

Publikováno v: Acta Physiologica. 201:413-426

Aim: At the interface of tissue and capillaries, pericytes (PC) may generate electrical signals to be conducted along the skeletal muscle vascular network, but they are functionally not well characterized. We aimed to isolate and cultivate muscle PC

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4f903f5cf41b8981df96f13298c00c86
https://doi.org/10.1111/j.1748-1716.2010.02206.x

The Tyrosine Phosphatase, SHP-1, Is a Negative Regulator of Endothelial Superoxide Formation

Autor: Torsten Gloe, Hanna Bridell, Florian Bassermann, Martin A. Buerkle, Barbara Engelbrecht, Ulrich Pohl, Hae-Young Sohn, Florian Krötz, Justus Duyster

Publikováno v: Journal of the American College of Cardiology. 45:1700-1706

ObjectivesWe investigated the role of SH2-domain containing phosphatase-1 (SHP-1) in endothelial reduced nicotinamide adenine dinucleotide (phosphate) (NAD[P]H)-oxidase-dependent oxidant production.BackgroundSuperoxide (O2·−) generation by endothe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcfd8cac7b68e6bee6fee057b3e5ff84
https://doi.org/10.1016/j.jacc.2005.02.039

Magnetofection Potentiates Gene Delivery to Cultured Endothelial Cells

Autor: Ulrich Pohl, Hae-Young Sohn, Torsten Gloe, Florian Krötz, Christian Plank

Publikováno v: Journal of Vascular Research. 40:425-434

Modification of cellular functions by overexpression of genes is increasingly practised for research of signalling pathways, but restricted by limitations of low efficiency. We investigated whether the novel technique of magnetofection (MF) could enh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbc63ab3df2e885e17b285f6f2cbf4fa
https://doi.org/10.1159/000073901

Shear Stress-induced Release of Basic Fibroblast Growth Factor from Endothelial Cells Is Mediated by Matrix Interaction via Integrin αVβ3

Autor: Hae Young Sohn, Torsten Gloe, Gerald A. Meininger, Ulrich Pohl

Publikováno v: Journal of Biological Chemistry. 277:23453-23458

Considering that chronic elevation of shear stress results in remodeling of the vasculature, we analyzed whether mechanical load could mediate basic fibroblast growth factor (bFGF) release and whether bFGF would act as mediator of shear stress-induce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e386bc2be4936e7d01e8e82b12db53b
https://doi.org/10.1074/jbc.m203889200