Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Torsten G. Loof"'
Autor:
Torsten G. Loof, Aaqib Sohail, Mahmoud M. Bahgat, Aravind Tallam, Haroon Arshad, Manas K. Akmatov, Marina C. Pils, Ulrike Heise, Andreas Beineke, Frank Pessler
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 8 (2018)
Background: Group A streptococci may induce lymphopenia, but the value of lymphocyte loss as early biomarkers for systemic spread and severe infection has not been examined systematically.Methods: We evaluated peripheral blood cell indices as biomark
Externí odkaz:
https://doaj.org/article/7a6a7c98bd3447e18f261c9daa7e3301
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 4 (2014)
The hemostatic system comprises platelet aggregation, coagulation and fibrinolysis and is a host defense mechanism that protects the integrity of the vascular system after tissue injury. During bacterial infections, the coagulation system cooperates
Externí odkaz:
https://doaj.org/article/ea1e458b6ee440049cf99c66dc986b30
Autor:
Zhi Wang, Christine Wilhelmsson, Pavel Hyrsl, Torsten G Loof, Pavel Dobes, Martina Klupp, Olga Loseva, Matthias Mörgelin, Jennifer Iklé, Richard M Cripps, Heiko Herwald, Ulrich Theopold
Publikováno v:
PLoS Pathogens, Vol 6, Iss 2, p e1000763 (2010)
Clotting systems are required in almost all animals to prevent loss of body fluids after injury. Here, we show that despite the risks associated with its systemic activation, clotting is a hitherto little appreciated branch of the immune system. We c
Externí odkaz:
https://doaj.org/article/04d733e57990492a87e41a1f3a61d082
Autor:
Eva Medina, Bhavya Chakrakodi, Marina C. Pils, Torsten G. Loof, Christin Deicke, Linda Johansson, Gerhard Dickneite
Publikováno v:
International Journal of Medical Microbiology. 306:572-579
Coagulation is a mechanism for wound healing after injury. Several recent studies delineate an additional role of the intrinsic pathway of coagulation, also known as the contact system, in the early innate immune response against bacterial infections
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d420557b78f4b7c0e25078665f173b2b
https://doi.org/10.1016/j.ijmm.2016.06.001
https://doi.org/10.1016/j.ijmm.2016.06.001
Autor:
Heiko Herwald, Simon J. Foster, Torsten G. Loof, Matthias Mörgelin, Marina C. Pils, Eva Medina, Oliver Goldmann, Yvonne Neumann, Clément Naudin
Publikováno v:
Microbiology. 161:621-627
Recent work has shown that coagulation and innate immunity are tightly interwoven host responses that help eradicate an invading pathogen. Some bacterial species, including Staphylococcus aureus, secrete pro-coagulant factors that, in turn, can modul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56da7122302be495ab70adc8d66d301e
https://doi.org/10.1099/mic.0.000019
https://doi.org/10.1099/mic.0.000019
Autor:
Torsten G, Loof, Aaqib, Sohail, Mahmoud M, Bahgat, Aravind, Tallam, Haroon, Arshad, Manas K, Akmatov, Marina C, Pils, Ulrike, Heise, Andreas, Beineke, Frank, Pessler
Publikováno v:
Frontiers in Cellular and Infection Microbiology
Background: Group A streptococci may induce lymphopenia, but the value of lymphocyte loss as early biomarkers for systemic spread and severe infection has not been examined systematically. Methods: We evaluated peripheral blood cell indices as biomar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c75e4af5bad5128ed1a2c42ea42acedc
https://pubmed.ncbi.nlm.nih.gov/29707522
https://pubmed.ncbi.nlm.nih.gov/29707522
Autor:
Steffen Bernecker, Rolf Jansen, Rolf Müller, Christine M. Gillen, Torsten G. Loof, Katharina Rox, Gursharan S. Chhatwal, Mark J. Walker
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
In contrast to mild infections of Group A Streptococcus (GAS) invasive infections of GAS still pose a serious health hazard: GAS disseminates from sterile sites into the blood stream or deep tissues and causes sepsis or necrotizing fasciitis. In this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9eb7e7777d1c237fe7e2c96ab7332eac
https://hdl.handle.net/10033/621136
https://hdl.handle.net/10033/621136
Autor:
Maren von Köckritz-Blickwede, Lara Mellinger, Jennifer Schöning, Thomas Vogl, Constantin von Kaisenberg, Beate Fehlhaber, Johanna Burgmann, Friederike Reuner, Stefanie Zenker, Shirin Glander, Marie S Bickes, Johannes Roth, Katarzyna Barczyk-Kahlert, Joachim L. Schultze, Sandra Pfeifer, Thomas Ulas, Torsten G Loof, Anna S. Heinemann, Sabine Pirr, Martin Stanulla, Lena Völlger, Dorothee Viemann, Sabine Schreek, Judith Friesenhagen, Lena Fischer-Riepe
Publikováno v:
Nature immunology 18(6), 622-632 (2017). doi:10.1038/ni.3745
The high risk of neonatal death from sepsis is thought to result from impaired responses by innate immune cells; however, the clinical observation of hyperinflammatory courses of neonatal sepsis contradicts this concept. Using transcriptomic, epigene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e4ecad34f573f2d5802aeb8933f93fc
https://pubmed.ncbi.nlm.nih.gov/28926540
https://pubmed.ncbi.nlm.nih.gov/28926540
Publikováno v:
The American Journal of Pathology. 176:754-763
Several in vitro studies have emphasized the importance of toll-like receptor/myeloid differentiation factor 88 (MyD88) signaling in the inflammatory response to Streptococcus pyogenes. Since the extent of inflammation has been implicated in the seve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcd6fb289641f22c6c8cee726e510d66
https://doi.org/10.2353/ajpath.2010.090422
https://doi.org/10.2353/ajpath.2010.090422
Autor:
Jasper J. Koehorst, Torsten G. Loof, Anshu Babbar, D. Patric Nitsche-Schmitz, Anne Fiebig, Peter J. Schaap, Andreas Itzek
Publikováno v:
International Journal of Medical Microbiology 305 (2015) 6
International Journal of Medical Microbiology, 305(6), 532-543
International Journal of Medical Microbiology, 305(6), 532-543
Streptococcus pyogenes serotype M1 is a frequent cause of severe infections in humans. Some M1 isolates are pathogenic in mice and used in studies on infection pathogenesis. We observed marked differences in murine infections caused by M1 strain SF37
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fa0baae8dcaf78207556e49ceafdfbb
https://pubmed.ncbi.nlm.nih.gov/26129624
https://pubmed.ncbi.nlm.nih.gov/26129624