Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Torsten Diesinger"'
Autor:
Torsten Diesinger, Alfred Lautwein, Vyacheslav Buko, Elena Belonovskaya, Oksana Lukivskaya, Elena Naruta, Siarhei Kirko, Viktor Andreev, Radovan Dvorsky, Dominik Buckert, Sebastian Bergler, Christian Renz, Dieter Müller‐Enoch, Thomas Wirth, Thomas Haehner
Publikováno v:
Physiological Reports, Vol 9, Iss 6, Pp n/a-n/a (2021)
Abstract Cytochrome P450 2E1 (CYP2E1)‐associated reactive oxygen species production plays an important role in the development and progression of inflammatory liver diseases such as alcoholic steatohepatitis. We developed two new inhibitors for thi
Externí odkaz:
https://doaj.org/article/7650c6afdea94e30a21387f69ebfb9bd
Autor:
Torsten Diesinger, Alfred Lautwein, Sebastian Bergler, Dominik Buckert, Christian Renz, Radovan Dvorsky, Vyacheslav Buko, Siarhei Kirko, Edith Schneider, Florian Kuchenbauer, Mukesh Kumar, Cagatay Günes, Felicitas Genze, Berthold Büchele, Thomas Simmet, Martin Haslbeck, Kai Masur, Thomas Barth, Dieter Müller-Enoch, Thomas Wirth, Thomas Haehner
Publikováno v:
Canadian Journal of Gastroenterology and Hepatology, Vol 2021 (2021)
Cytochrome P450 2E1 (CYP2E1) is a key target protein in the development of alcoholic and nonalcoholic fatty liver disease (FLD). The pathophysiological correlate is the massive production of reactive oxygen species. The role of CYP2E1 in the developm
Externí odkaz:
https://doaj.org/article/e74a70f467514028b4d33139a1dbe072
Autor:
Torsten Diesinger, Vyacheslav Buko, Alfred Lautwein, Radovan Dvorsky, Elena Belonovskaya, Oksana Lukivskaya, Elena Naruta, Siarhei Kirko, Viktor Andreev, Dominik Buckert, Sebastian Bergler, Christian Renz, Edith Schneider, Florian Kuchenbauer, Mukesh Kumar, Cagatay Günes, Berthold Büchele, Thomas Simmet, Dieter Müller-Enoch, Thomas Wirth, Thomas Haehner
Publikováno v:
PLoS ONE, Vol 15, Iss 7, p e0235990 (2020)
Background and aimsAlcoholic steatohepatitis (ASH)-the inflammation of fatty liver-is caused by chronic alcohol consumption and represents one of the leading chronic liver diseases in Western Countries. ASH can lead to organ dysfunction or progress t
Externí odkaz:
https://doaj.org/article/67889073cb194f45b24f6833841d8c81
Autor:
Elena Belonovskaya, Dominik Buckert, Siarhei Kirko, Oksana Lukivskaya, Christian Renz, Viktor Andreev, Sebastian Bergler, Vyacheslav Buko, Thomas Wirth, Radovan Dvorsky, Thomas Haehner, Torsten Diesinger, Alfred Lautwein, Dieter Müller-Enoch, Elena Naruta
Publikováno v:
Physiological Reports
Physiological Reports, Vol 9, Iss 6, Pp n/a-n/a (2021)
Physiological Reports, Vol 9, Iss 6, Pp n/a-n/a (2021)
Cytochrome P450 2E1 (CYP2E1)‐associated reactive oxygen species production plays an important role in the development and progression of inflammatory liver diseases such as alcoholic steatohepatitis. We developed two new inhibitors for this isoenzy
Autor:
Florian Kuchenbauer, Felicitas Genze, Cagatay Günes, Thomas Wirth, Vyacheslav Buko, Sebastian Bergler, Christian Renz, Thomas F. E. Barth, Edith Schneider, Siarhei Kirko, Mukesh Kumar, Dominik Buckert, Thomas Simmet, Radovan Dvorsky, Martin Haslbeck, Thomas Haehner, Torsten Diesinger, Kai Masur, Alfred Lautwein, Dieter Müller-Enoch, Berthold Büchele
Publikováno v:
Canadian Journal of Gastroenterology and Hepatology, Vol 2021 (2021)
Canadian Journal of Gastroenterology & Hepatology
Canadian Journal of Gastroenterology & Hepatology
Cytochrome P450 2E1 (CYP2E1) is a key target protein in the development of alcoholic and nonalcoholic fatty liver disease (FLD). The pathophysiological correlate is the massive production of reactive oxygen species. The role of CYP2E1 in the developm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aece6925b01657f18020b2fe74eee71c
https://mediatum.ub.tum.de/1649993
https://mediatum.ub.tum.de/1649993
Autor:
Berthold Büchele, Elena Belonovskaya, Cagatay Günes, Oksana Lukivskaya, Florian Kuchenbauer, Siarhei Kirko, Thomas Wirth, Thomas Simmet, Edith Schneider, Dominik Buckert, Radovan Dvorsky, Alfred Lautwein, Dieter Müller-Enoch, Viktor Andreev, Sebastian Bergler, Vyacheslav Buko, Thomas Haehner, Christian Renz, Torsten Diesinger, Elena Naruta, Mukesh Kumar
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 7, p e0235990 (2020)
PLoS ONE, Vol 15, Iss 7, p e0235990 (2020)
Background and aimsAlcoholic steatohepatitis (ASH)-the inflammation of fatty liver-is caused by chronic alcohol consumption and represents one of the leading chronic liver diseases in Western Countries. ASH can lead to organ dysfunction or progress t
Autor:
Viktor Andreev, Oksana Lukivskaya, Elena Naruta, Thomas Haehner, Torsten Diesinger, Elena Belonovskaya, Thomas Wirth, Christian Renz, Radovan Dvorsky, Vyacheslav Buko, Dominik Buckert, Bergler Sebastian, Siarhei Kirko, Alfred Lautwein, Dieter Müller-Enoch
Cytochrome P450 2E1 (CYP2E1) and its production of ROS play an essential role in the development and progression of inflammatory liver diseases such as alcoholic steatohepatitis. For this isoenzyme we have developed two new inhibitors - 12-imidazolyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef06f7f6a6050ce0f6ff6518393747ab
Publikováno v:
Zeitschrift für Naturforschung C. 59:599-605
The inhibitory potency of four alkylphospholipids: rac-1-O-phosphocholine-2-hydroxy-octadecane (rac-2-OH), rac-1-O-phosphocholine-2-O-acetyl-octadecane (rac-2-O-acetyl), rac-1- O-phosphocholine-2-amino-octadecane (rac-2-NH2) and rac-1-O-phosphocholin