Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Torsten Burkholz"'
Autor:
Dominika Mániková, Lucia Medvecová Letavayová, Danuša Vlasáková, Pavol Košík, Ethiene Castellucci Estevam, Muhammad Jawad Nasim, Martin Gruhlke, Alan Slusarenko, Torsten Burkholz, Claus Jacob, Miroslav Chovanec
Publikováno v:
Molecules, Vol 19, Iss 8, Pp 12258-12279 (2014)
Redox-modulating compounds derived from natural sources, such as redox active secondary metabolites, are currently of considerable interest in the field of chemoprevention, drug and phytoprotectant development. Unfortunately, the exact and occasional
Externí odkaz:
https://doaj.org/article/155402058c834f35892a1a6421b3f07f
Autor:
Tanya Schwab, Claus Jacob, Michaela Leroch, Matthias Hahn, Lalla Aïcha Ba, Torsten Burkholz, Khairan Khairan, Markus Klotz, Karl-Herbert Schaefer
Publikováno v:
Current Pharmacology Reports. 5:174-187
This article provides a brief overview of electrochemical potential-biological activity relationships of natural and synthetic cyclic sulfur-containing molecules against Steinernema feltiae, Botrytis cinerea, and Neuro 2a cell line (from murine neuro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::092c73c6adf6a5fd3bac8ad8addc6ac6
https://doi.org/10.1007/s40495-019-00179-4
https://doi.org/10.1007/s40495-019-00179-4
Autor:
Khairan,, Torsten, Burkholz, Mareike, Kelkel, Vincent, Jamier, Karl-Herbert, Schäfer, Claus, Jacob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=intech______::f4143da384ff14e5741ca3036d445187
http://www.intechopen.com/articles/show/title/study-of-the-cytotoxic-activity-of-haarlem-oil-on-different-cell-lines-and-a-higher-organism-steiner
http://www.intechopen.com/articles/show/title/study-of-the-cytotoxic-activity-of-haarlem-oil-on-different-cell-lines-and-a-higher-organism-steiner
Autor:
Anne-Kathrin Baltes, Brigitte Czepukojc, Mathias Montenarh, Marc Diederich, Mario Dicato, Franz Salm, Claudia Cerella, Carolin C. Schneider, Uma M. Viswanathan, Claus Jacob, Torsten Burkholz, Mareike Kelkel
Publikováno v:
Food and Chemical Toxicology. 64:249-257
Natural polysulfanes including diallyltrisulfide (DATS) and diallyltetrasulfide (DATTS) from garlic possess antimicrobial, chemopreventive and anticancer properties. However these compounds exhibit chemical instability and reduced solubility, which p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b247fba9863c6f405c5268be86646365
https://doi.org/10.1016/j.fct.2013.10.020
https://doi.org/10.1016/j.fct.2013.10.020
Autor:
Frank Hannemann, Khairan Khairan, Tomislav Buric, Alexandra K. Kiemer, Gilbert Kirsch, Armen Trchounian, Zhanjie Xu, Inga Bazukyan, Benjamin Hanf, Ingolf Bernhardt, Nathaniel Edward Bennett Saidu, Mathias Montenarh, Uma M. Viswanathan, Karl-Herbert Schäfer, Claus Jacob, Torsten Burkholz, Peng Du, Britta Diesel
Publikováno v:
MedChemComm
MedChemComm, Royal Society of Chemistry, 2014, 5 (1), pp.25-31. ⟨10.1039/c3md00204g⟩
MedChemComm, Royal Society of Chemistry, 2014, 5 (1), pp.25-31. ⟨10.1039/c3md00204g⟩
International audience; Several amphiphilic, chalcogen-based redox modulators have been synthesized which exhibit a widespread, yet in some instances also selective, biological activity which is most likely based on their ability to modulate the intr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8e9140fe9278858bcfa37af248e4bdb
https://doi.org/10.1039/c3md00204g
https://doi.org/10.1039/c3md00204g
Autor:
Claus Jacob, Torsten Burkholz, Karol Ondrias, Zuzana Tomaskova, Peter Docolomansky, Ladislav Habala, Marian Grman, Anton Misak, Anna Bertova
Publikováno v:
General physiology and biophysics. 32:429-441
We studied the involvement of O2, pH and low molecular thiols in H2S-induced decomposition of S-nitrosoglutathione (GSNO). The GSNO decomposition - •NO release was evaluated by UV-VIS spectroscopy and Griess assay. The H2S donor Na2S was used. O2 s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0bbe6450148c927d45bb77389cec344
https://doi.org/10.4149/gpb_2013026
https://doi.org/10.4149/gpb_2013026
Publikováno v:
Zeitschrift für Physikalische Chemie. 227:691-706
In Biology, numerous cellular signalling and control networks are centred around redox active chalcogen species, such as the thiol group of cysteine, the sulfide of methionine and the selenol(ate) of the unusual amino acid selenocysteine. These amino
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7904d6166656ee3a7e3e5bd5d3808b3
https://doi.org/10.1524/zpch.2013.0321
https://doi.org/10.1524/zpch.2013.0321
Publikováno v:
Phosphorus, Sulfur, and Silicon and the Related Elements. 188:446-453
Naturally occurring polysulfanes often exhibit a wide spectrum of biological activity, which results from their ability to react with, and hence modify cysteine residues in key proteins and enzymes of the cellular thiolstat. Such interactions frequen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f00603f6a6f8da93393b5546aa0011e9
https://doi.org/10.1080/10426507.2012.746691
https://doi.org/10.1080/10426507.2012.746691
Autor:
Claus Jacob, Torsten Burkholz, Miroslav Chovanec, Alexandra K. Kiemer, Alan J. Slusarenko, Uma M. Viswanathan, Dominika Mániková, Mandy Doering, Martin C.H. Gruhlke, Britta Diesel
Publikováno v:
Tetrahedron. 68:10577-10585
Various selenium- and tellurium-containing molecules are able to modulate the intracellular redox state of cells, an effect which may be used for the (selective) targeting of cancer cells, which are naturally under oxidative stress (OS). As macrophag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::474f766e86675a802901042480c2aee2
https://doi.org/10.1016/j.tet.2012.09.021
https://doi.org/10.1016/j.tet.2012.09.021