Zobrazeno 1 - 10
of 296
pro vyhledávání: '"Torsten, Seemann"'
Autor:
Michael B Hall, Ryan R Wick, Louise M Judd, An N Nguyen, Eike J Steinig, Ouli Xie, Mark Davies, Torsten Seemann, Timothy P Stinear, Lachlan Coin
Publikováno v:
eLife, Vol 13 (2024)
Variant calling is fundamental in bacterial genomics, underpinning the identification of disease transmission clusters, the construction of phylogenetic trees, and antimicrobial resistance detection. This study presents a comprehensive benchmarking o
Externí odkaz:
https://doaj.org/article/cd1d06c346284d23b31c3ead2e1180fc
Autor:
Sacha J Pidot, Stephan Klatt, Louis S Ates, Wafa Frigui, Fadel Sayes, Laleh Majlessi, Hiroshi Izumi, Ian R Monk, Jessica L Porter, Vicki Bennett-Wood, Torsten Seemann, Ashley Otter, George Taiaroa, Gregory M Cook, Nicholas West, Nicholas J Tobias, John A Fuerst, Michael D Stutz, Marc Pellegrini, Malcolm McConville, Roland Brosch, Timothy P Stinear
Publikováno v:
PLoS Pathogens, Vol 20, Iss 8, p e1012440 (2024)
Reconstructing the evolutionary origins of Mycobacterium tuberculosis, the causative agent of human tuberculosis, has helped identify bacterial factors that have led to the tubercle bacillus becoming such a formidable human pathogen. Here we report t
Externí odkaz:
https://doaj.org/article/c05a679dcd724c87b14f99cec3647995
Autor:
Sara E. Zufan, Karolina Mercoulia, Jason C. Kwong, Louise M. Judd, Benjamin P. Howden, Torsten Seemann, Timothy P. Stinear
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 1 (2024)
ABSTRACT Hepatitis A virus (HAV) infections are an increasing public health concern in low-endemicity regions due to outbreaks from food-borne infections and sustained transmission among vulnerable groups, including persons experiencing homelessness,
Externí odkaz:
https://doaj.org/article/11c666347e524d568b72856584d33c99
Autor:
Liam K. R. Sharkey, Romain Guerillot, Calum J. Walsh, Adrianna M. Turner, Jean Y. H. Lee, Stephanie L. Neville, Stephan Klatt, Sarah L. Baines, Sacha J. Pidot, Fernando J. Rossello, Torsten Seemann, Hamish E. G. McWilliam, Ellie Cho, Glen P. Carter, Benjamin P. Howden, Christopher A. McDevitt, Abderrahman Hachani, Timothy P. Stinear, Ian R. Monk
Publikováno v:
mBio, Vol 14, Iss 6 (2023)
ABSTRACTAmong the 16 two-component systems in the opportunistic human pathogen Staphylococcus aureus, only WalKR is essential. Like the orthologous systems in other Bacillota, S. aureus WalKR controls autolysins involved in peptidoglycan remodeling a
Externí odkaz:
https://doaj.org/article/b925679724c74489887fb31d58cddb66
Autor:
Andre Mu, William P. Klare, Sarah L. Baines, C. N. Ignatius Pang, Romain Guérillot, Nichaela Harbison-Price, Nadia Keller, Jonathan Wilksch, Nguyen Thi Khanh Nhu, Minh-Duy Phan, Bernhard Keller, Brunda Nijagal, Dedreia Tull, Saravanan Dayalan, Hwa Huat Charlie Chua, Dominik Skoneczny, Jason Koval, Abderrahman Hachani, Anup D. Shah, Nitika Neha, Snehal Jadhav, Sally R. Partridge, Amanda J. Cork, Kate Peters, Olivia Bertolla, Stephan Brouwer, Steven J. Hancock, Laura Álvarez-Fraga, David M. P. De Oliveira, Brian Forde, Ashleigh Dale, Warasinee Mujchariyakul, Calum J. Walsh, Ian Monk, Anna Fitzgerald, Mabel Lum, Carolina Correa-Ospina, Piklu Roy Chowdhury, Robert G. Parton, James De Voss, James Beckett, Francois Monty, Jessica McKinnon, Xiaomin Song, John R. Stephen, Marie Everest, Matt I. Bellgard, Matthew Tinning, Michael Leeming, Dianna Hocking, Leila Jebeli, Nancy Wang, Nouri Ben Zakour, Serhat A. Yasar, Stefano Vecchiarelli, Tonia Russell, Thiri Zaw, Tyrone Chen, Don Teng, Zena Kassir, Trevor Lithgow, Adam Jenney, Jason N. Cole, Victor Nizet, Tania C. Sorrell, Anton Y. Peleg, David L. Paterson, Scott A. Beatson, Jemma Wu, Mark P. Molloy, Anna E. Syme, Robert J. A. Goode, Adam A. Hunter, Grahame Bowland, Nicholas P. West, Marc R. Wilkins, Steven P. Djordjevic, Mark R. Davies, Torsten Seemann, Benjamin P. Howden, Dana Pascovici, Sonika Tyagi, Ralf B. Schittenhelm, David P. De Souza, Malcolm J. McConville, Jonathan R. Iredell, Stuart J. Cordwell, Richard A. Strugnell, Timothy P. Stinear, Mark A. Schembri, Mark J. Walker
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Severe sepsis has a high mortality rate. Here, the authors provide genomic, transcriptomic, proteomic and metabolomic data across four sepsis-causing pathogens and identify a signature of global increase in fatty acid and lipid biosynthesis as well a
Externí odkaz:
https://doaj.org/article/6d65b18b91de403488fe5eca204df6be
Autor:
Norelle L. Sherry, Kristy A. Horan, Susan A. Ballard, Anders Gonҫalves da Silva, Claire L. Gorrie, Mark B. Schultz, Kerrie Stevens, Mary Valcanis, Michelle L. Sait, Timothy P. Stinear, Benjamin P. Howden, Torsten Seemann
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
The implementation of genomics for identification and surveillance of antimicrobial resistance (AMR) in clinical laboratories remains challenging. Here, Sherry et al. present a bioinformatics platform for detection of AMR determinants from whole-geno
Externí odkaz:
https://doaj.org/article/5dc17a638e5c400fb37025cfb5f853eb
Autor:
Freya Hogarth, Pasqualina Coffey, Laura Goddard, Sarah Lewis, Shereen Labib, Mathilda Wilmot, Patiyan Andersson, Norelle Sherry, Torsten Seemann, Benjamin P. Howden, Kevin Freeman, Robert Baird, Ian Hosegood, Kathleen McDermott, Nick Walsh, Ben Polkinghorne, Catherine Marshall, Jane Davies, Vicki Krause, Ella M. Meumann
Publikováno v:
Emerging Infectious Diseases, Vol 28, Iss 7, Pp 1527-1530 (2022)
Epidemiologic and genomic investigation of SARS-CoV-2 infections associated with 2 repatriation flights from India to Australia in April 2021 indicated that 4 passengers transmitted SARS-CoV-2 to >11 other passengers. Results suggest transmission des
Externí odkaz:
https://doaj.org/article/4b0ef18021f14e3b95b790986a8208c9
Autor:
Wuji Zhang, Brendon Y. Chua, Kevin J. Selva, Lukasz Kedzierski, Thomas M. Ashhurst, Ebene R. Haycroft, Suzanne K. Shoffner-Beck, Luca Hensen, David F. Boyd, Fiona James, Effie Mouhtouris, Jason C. Kwong, Kyra Y. L. Chua, George Drewett, Ana Copaescu, Julie E. Dobson, Louise C. Rowntree, Jennifer R. Habel, Lilith F. Allen, Hui-Fern Koay, Jessica A. Neil, Matthew J. Gartner, Christina Y. Lee, Patiyan Andersson, Sadid F. Khan, Luke Blakeway, Jessica Wisniewski, James H. McMahon, Erica E. Vine, Anthony L. Cunningham, Jennifer Audsley, Irani Thevarajan, Torsten Seemann, Norelle L. Sherry, Fatima Amanat, Florian Krammer, Sarah L. Londrigan, Linda M. Wakim, Nicholas J. C. King, Dale I. Godfrey, Laura K. Mackay, Paul G. Thomas, Suellen Nicholson, Kelly B. Arnold, Amy W. Chung, Natasha E. Holmes, Olivia C. Smibert, Jason A. Trubiano, Claire L. Gordon, Thi H. O. Nguyen, Katherine Kedzierska
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
The immune response to SARS-CoV-2 infection is variable but has been linked to prognosis and the development of severe immunopathology. Here the authors assess a range of immune parameters in both peripheral blood and respiratory samples, providing a
Externí odkaz:
https://doaj.org/article/3dbf74c705f948919beba2c6dc7dada4
Autor:
Tuyet Hoang, Anders Gonçalves da Silva, Amy V. Jennison, Deborah A. Williamson, Benjamin P. Howden, Torsten Seemann
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-4 (2022)
The COVID-19 pandemic has accelerated the demand for near real-time analysis and dissemination of pathogen genomic data. In this comment, the authors describe how Australia has developed and rolled out its SARS-CoV-2 genomics platform, AusTrakka, and
Externí odkaz:
https://doaj.org/article/45f0f1ea19d44eab8ebce4d7ca57cf7f
Autor:
Charlie Higgs, Norelle L. Sherry, Torsten Seemann, Kristy Horan, Hasini Walpola, Paul Kinsella, Katherine Bond, Deborah A. Williamson, Caroline Marshall, Jason C. Kwong, M. Lindsay Grayson, Timothy P. Stinear, Claire L. Gorrie, Benjamin P. Howden
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Vancomycin-resistant Enterococcus faecium is an important healthcare-associated pathogen and genomic analyses could inform targeted interventions. Here, the authors optimise an analysis pipeline for identification of putative transmission events usin
Externí odkaz:
https://doaj.org/article/9085c898931b450b8fc805f65670d549