Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Torsten, Lowin"'
Publikováno v:
Journal of Inflammation, Vol 20, Iss 1, Pp 1-15 (2023)
Abstract Background Catecholamines are major neurotransmitters of the sympathetic nervous system (SNS) and they are of pivotal importance in regulating numerous physiological and pathological processes. Rheumatoid arthritis (RA) is influenced by the
Externí odkaz:
https://doaj.org/article/f70e8e10a92c4e6a8e7b2a6c8392d999
Autor:
Nadine Honke, Torsten Lowin, Birgit Opgenoorth, Namir Shaabani, Alexander Lautwein, John R. Teijaro, Matthias Schneider, Georg Pongratz
Publikováno v:
PLoS Biology, Vol 20, Iss 1 (2022)
The sympathetic nervous system (SNS) contributes to immune balance by promoting anti-inflammatory B cells. However, whether B cells possess a self-regulating mechanism by which they modulate regulatory B cell (Breg) function is not well understood. I
Externí odkaz:
https://doaj.org/article/9a8cde83436a4dcabfaf3c891add29ec
Autor:
Silvia Piantoni, Francesca Regola, Stefania Masneri, Michele Merletti, Torsten Lowin, Paolo Airò, Angela Tincani, Franco Franceschini, Laura Andreoli, Georg Pongratz
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Background: Patients with systemic lupus erythematosus (SLE) show increased serum levels of tumor necrosis factor (TNF)/TNF receptor (R) superfamily member, e.g. BAFF (B lymphocyte stimulator). Belimumab, a monoclonal antibody against soluble BAFF, i
Externí odkaz:
https://doaj.org/article/a3820d5e7a8f427ea9c50a3b3ff310c5
Publikováno v:
Biomedicines, Vol 10, Iss 5, p 1118 (2022)
δ9-Tetrahydrocannabinol (THC) has demonstrated anti-inflammatory effects in animal models of arthritis, but its mechanism of action and cellular targets are still unclear. The purpose of this study is to elucidate the effects of THC (0.1–25 µM) o
Externí odkaz:
https://doaj.org/article/bd04a7a9b83843b9b0351f7790982be6
Autor:
Francesca Regola, Silvia Piantoni, Torsten Lowin, Silvia Archetti, Rossella Reggia, Rajesh Kumar, Franco Franceschini, Paolo Airò, Angela Tincani, Laura Andreoli, Georg Pongratz
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Introduction: Belimumab is a monoclonal antibody against soluble BLyS used for treatment of refractory Systemic Lupus Erythematosus (SLE). Although B cells are the main target of this therapy, a BLyS-dependent T cell activation pathway has also been
Externí odkaz:
https://doaj.org/article/4071a9122a604a739cf044eede64af12
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 1; Pages: 855
Since its medical legalization, cannabis preparations containing the major phytocannabinoids (cannabidiol (CBD) and δ9-tetrahydrocannabinol (THC)) have been used by patients with rheumatoid arthritis (RA) to alleviate pain and inflammation. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::910c79c6398ad0188e9b5f30c7bcac52
Publikováno v:
Cannabis and cannabinoid research.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec45b50bd963b2279c6c8a04bba9ade0
https://pubmed.ncbi.nlm.nih.gov/35920857
https://pubmed.ncbi.nlm.nih.gov/35920857
Autor:
Torsten, Lowin, Ren, Tingting, Julia, Zurmahr, Tim, Classen, Matthias, Schneider, Georg, Pongratz
Publikováno v:
Cell Death and Disease, Vol 11, Iss 8, Pp 1-11 (2020)
Cell Death & Disease
Cell Death & Disease
Cannabidiol (CBD) is a non-intoxicating phytocannabinoid from cannabis sativa that has demonstrated anti-inflammatory effects in several inflammatory conditions including arthritis. However, CBD binds to several receptors and enzymes and, therefore,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::345b19b730ed62c97f7d2864b19377ba
http://link.springer.com/article/10.1038/s41419-020-02892-1
http://link.springer.com/article/10.1038/s41419-020-02892-1
Autor:
Matthias Schneider, Ralph Brinks, Petra Budde, Peter Schulz-Knappe, Stefan Vordenbäumen, Hans-Dieter Zucht, Ellen Bleck, Georg Pongratz, Rebecca Fischer-Betz, Annika Hoyer, Torsten Lowin
Publikováno v:
Arthritis & Rheumatology. 71:736-743
OBJECTIVE To investigate the role of epitope spreading in established systemic lupus erythematosus (SLE). METHODS IgG autoantibody reactivity with 398 distinct recombinant proteins was measured over a period of 6 years in 69 SLE patients and compared
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba0d9899959d91c3df419b529633ccce
https://doi.org/10.1002/art.40788
https://doi.org/10.1002/art.40788
Background: Rheumatoid arthritis (RA) is influenced by the activity of the sympathetic nervous system (SNS). In animal models of RA, the SNS promotes severity of the disease and its manipulation modulates experimental arthritis depending on timing of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b06898738501cd865da01f049b841b7d
https://doi.org/10.21203/rs.3.rs-299542/v1
https://doi.org/10.21203/rs.3.rs-299542/v1
