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Two-Component Nanoparticle Vaccine Displaying Glycosylated Spike S1 Domain Induces Neutralizing Antibody Response against SARS-CoV-2 Variants.

Autor: van Oosten L; Laboratory of Virology, Wageningen University, Wageningen, The Netherlands., Altenburg JJ; Bioprocess Engineering, Wageningen University, Wageningen, The Netherlands., Fougeroux C; AdaptVac Aps, Hørsholm, Denmark., Geertsema C; Laboratory of Virology, Wageningen University, Wageningen, The Netherlands., van den End F; Bioprocess Engineering, Wageningen University, Wageningen, The Netherlands., Evers WAC; Bioprocess Engineering, Wageningen University, Wageningen, The Netherlands., Westphal AH; Laboratory of Biochemistry, Wageningen University, Wageningen, the Netherlands., Lindhoud S; Laboratory of Biochemistry, Wageningen University, Wageningen, the Netherlands., van den Berg W; Laboratory of Biochemistry, Wageningen University, Wageningen, the Netherlands., Swarts DC; Laboratory of Biochemistry, Wageningen University, Wageningen, the Netherlands., Deurhof L; Laboratory of Phytopathology, Wageningen University, Wageningen, The Netherlands., Suhrbier A; QIMR Berghofer Medical Research Institutegrid.1049.c, Brisbane, Australia., Le TT; QIMR Berghofer Medical Research Institutegrid.1049.c, Brisbane, Australia., Torres Morales S; Department of Medical Microbiology, Leiden University Medical Centergrid.10419.3d, Leiden, Netherlands., Myeni SK; Department of Medical Microbiology, Leiden University Medical Centergrid.10419.3d, Leiden, Netherlands., Kikkert M; Department of Medical Microbiology, Leiden University Medical Centergrid.10419.3d, Leiden, Netherlands., Sander AF; AdaptVac Aps, Hørsholm, Denmark.; Centre for Medical Parasitology at Department for Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagengrid.5254.6, Copenhagen, Denmark., de Jongh WA; AdaptVac Aps, Hørsholm, Denmark.; Centre for Medical Parasitology at Department for Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagengrid.5254.6, Copenhagen, Denmark., Dagil R; Centre for Medical Parasitology at Department for Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagengrid.5254.6, Copenhagen, Denmark., Nielsen MA; Centre for Medical Parasitology at Department for Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagengrid.5254.6, Copenhagen, Denmark., Salanti A; Centre for Medical Parasitology at Department for Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagengrid.5254.6, Copenhagen, Denmark., Søgaard M; ExpreS2ion Biotechnologies Aps, Hørsholm, Denmark., Keijzer TMP; Applikon Biotechnology BV, Delft, The Netherlands., Weijers D; Laboratory of Biochemistry, Wageningen University, Wageningen, the Netherlands., Eppink MHM; Bioprocess Engineering, Wageningen University, Wageningen, The Netherlands., Wijffels RH; Bioprocess Engineering, Wageningen University, Wageningen, The Netherlands., van Oers MM; Laboratory of Virology, Wageningen University, Wageningen, The Netherlands., Martens DE; Bioprocess Engineering, Wageningen University, Wageningen, The Netherlands., Pijlman GP; Laboratory of Virology, Wageningen University, Wageningen, The Netherlands.

Publikováno v: MBio [mBio] 2021 Oct 26; Vol. 12 (5), pp. e0181321. Date of Electronic Publication: 2021 Oct 12.