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Protein-truncating variants in BSNare associated with severe adult-onset obesity, type 2 diabetes and fatty liver disease

Autor: Zhao, Yajie, Chukanova, Maria, Kentistou, Katherine A., Fairhurst-Hunter, Zammy, Siegert, Anna Maria, Jia, Raina Y., Dowsett, Georgina K. C., Gardner, Eugene J., Lawler, Katherine, Day, Felix R., Kaisinger, Lena R., Tung, Yi-Chun Loraine, Lam, Brian Yee Hong, Chen, Hsiao-Jou Cortina, Wang, Quanli, Berumen-Campos, Jaime, Kuri-Morales, Pablo, Tapia-Conyer, Roberto, Alegre-Diaz, Jesus, Barroso, Inês, Emberson, Jonathan, Torres, Jason M., Collins, Rory, Saleheen, Danish, Smith, Katherine R., Paul, Dirk S., Merkle, Florian, Farooqi, I. Sadaf, Wareham, Nick J., Petrovski, Slavé, O’Rahilly, Stephen, Ong, Ken K., Yeo, Giles S. H., Perry, John R. B.

Publikováno v: Nature Genetics; April 2024, Vol. 56 Issue: 4 p579-584, 6p

Extended data for study 'Inferring causal genes at type 2 diabetes GWAS loci through chromosome interactions in islet cells'

Autor: Torres, Jason M.

A systematic comparison of chromatin interaction maps in primary human islets and endoC-betaH1 cells at loci associated with type 2 diabetes, obtained from Hi-C and/or NG Capture-C assays.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::26cb14ac298814c7823a2ee36e8a10c8

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Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

Autor: Mahajan, Anubha, Spracklen, Cassandra N., Zhang, Weihua, Ng, Maggie C. Y., Petty, Lauren E., Kitajima, Hidetoshi, Yu, Grace Z., Rüeger, Sina, Speidel, Leo, Kim, Young Jin, Horikoshi, Momoko, Mercader, Josep M., Taliun, Daniel, Moon, Sanghoon, Kwak, Soo-heon, Robertson, Neil R., Rayner, Nigel W., Loh, Marie, Kim, Bong-jo, Chiou, Joshua, Miguel-escalada, Irene, Della Briotta Parolo, Pietro, Lin, Kuang, Bragg, Fiona, Preuss, Michael H., Takeuchi, Fumihiko, Nano, Jana, Guo, Xiuqing, Lamri, Amel, Nakatochi, Masahiro, Scott, Robert A., Lee, Jung-jin, Huerta-chagoya, Alicia, Graff, Mariaelisa, Chai, Jin-fang, Parra, Esteban J., Yao, Jie, Bielak, Lawrence F., Tabara, Yasuharu, Hai, Yang, Steinthorsdottir, Valgerdur, Cook, James P., Kals, Mart, Grarup, Niels, Schmidt, Ellen M., Pan, Ian, Sofer, Tamar, Wuttke, Matthias, Sarnowski, Chloe, Gieger, Christian, Nousome, Darryl, Trompet, Stella, Long, Jirong, Sun, Meng, Tong, Lin, Chen, Wei-min, Ahmad, Meraj, Noordam, Raymond, Lim, Victor J. Y., Tam, Claudia H. T., Joo, Yoonjung Yoonie, Chen, Chien-hsiun, Raffield, Laura M., Lecoeur, Cécile, Prins, Bram Peter, Nicolas, Aude, Yanek, Lisa R., Chen, Guanjie, Jensen, Richard A., Tajuddin, Salman, Kabagambe, Edmond K., An, Ping, Xiang, Anny H., Choi, Hyeok Sun, Cade, Brian E., Tan, Jingyi, Flanagan, Jack, Abaitua, Fernando, Adair, Linda S., Adeyemo, Adebowale, Aguilar-salinas, Carlos A., Akiyama, Masato, Anand, Sonia S., Bertoni, Alain, Bian, Zheng, Bork-jensen, Jette, Brandslund, Ivan, Brody, Jennifer A., Brummett, Chad M., Buchanan, Thomas A., Canouil, Mickaël, Chan, Juliana C. N., Chang, Li-ching, Chee, Miao-li, Chen, Ji, Chen, Shyh-huei, Chen, Yuan-tsong, Chen, Zhengming, Chuang, Lee-ming, Cushman, Mary, Das, Swapan K., De Silva, H. Janaka, Dedoussis, George, Dimitrov, Latchezar, Doumatey, Ayo P., Du, Shufa, Duan, Qing, Eckardt, Kai-uwe, Emery, Leslie S., Evans, Daniel S., Evans, Michele K., Fischer, Krista, Floyd, James S., Ford, Ian, Fornage, Myriam, Franco, Oscar H., Frayling, Timothy M., Freedman, Barry I., Fuchsberger, Christian, Genter, Pauline, Gerstein, Hertzel C., Giedraitis, Vilmantas, González-villalpando, Clicerio, González-villalpando, Maria Elena, Goodarzi, Mark O., Gordon-larsen, Penny, Gorkin, David, Gross, Myron, Guo, Yu, Hackinger, Sophie, Han, Sohee, Hattersley, Andrew T., Herder, Christian, Howard, Annie-green, Hsueh, Willa, Huang, Mengna, Huang, Wei, Hung, Yi-jen, Hwang, Mi Yeong, Hwu, Chii-min, Ichihara, Sahoko, Ikram, Mohammad Arfan, Ingelsson, Martin, Islam, Md Tariqul, Isono, Masato, Jang, Hye-mi, Jasmine, Farzana, Jiang, Guozhi, Jonas, Jost B., Jørgensen, Marit E., Jørgensen, Torben, Kamatani, Yoichiro, Kandeel, Fouad R., Kasturiratne, Anuradhani, Katsuya, Tomohiro, Kaur, Varinderpal, Kawaguchi, Takahisa, Keaton, Jacob M., Kho, Abel N., Khor, Chiea-chuen, Kibriya, Muhammad G., Kim, Duk-hwan, Kohara, Katsuhiko, Kriebel, Jennifer, Kronenberg, Florian, Kuusisto, Johanna, Läll, Kristi, Lange, Leslie A., Lee, Myung-shik, Lee, Nanette R., Leong, Aaron, Li, Liming, Li, Yun, Li-gao, Ruifang, Ligthart, Symen, Lindgren, Cecilia M., Linneberg, Allan, Liu, Ching-ti, Liu, Jianjun, Locke, Adam E., Louie, Tin, Luan, Jian’an, Luk, Andrea O., Luo, Xi, Lv, Jun, Lyssenko, Valeriya, Mamakou, Vasiliki, Mani, K. Radha, Meitinger, Thomas, Metspalu, Andres, Morris, Andrew D., Nadkarni, Girish N., Nadler, Jerry L., Nalls, Michael A., Nayak, Uma, Nongmaithem, Suraj S., Ntalla, Ioanna, Okada, Yukinori, Orozco, Lorena, Patel, Sanjay R., Pereira, Mark A., Peters, Annette, Pirie, Fraser J., Porneala, Bianca, Prasad, Gauri, Preissl, Sebastian, Rasmussen-torvik, Laura J., Reiner, Alexander P., Roden, Michael, Rohde, Rebecca, Roll, Kathryn, Sabanayagam, Charumathi, Sander, Maike, Sandow, Kevin, Sattar, Naveed, Schönherr, Sebastian, Schurmann, Claudia, Shahriar, Mohammad, Shi, Jinxiu, Shin, Dong Mun, Shriner, Daniel, Smith, Jennifer A., So, Wing Yee, Stančáková, Alena, Stilp, Adrienne M., Strauch, Konstantin, Suzuki, Ken, Takahashi, Atsushi, Taylor, Kent D., Thorand, Barbara, Thorleifsson, Gudmar, Thorsteinsdottir, Unnur, Tomlinson, Brian, Torres, Jason M., Tsai, Fuu-jen, Tuomilehto, Jaakko, Tusie-luna, Teresa, Udler, Miriam S., Valladares-salgado, Adan, Van Dam, Rob M., Van Klinken, Jan B., Varma, Rohit, Vujkovic, Marijana, Wacher-rodarte, Niels, Wheeler, Eleanor, Whitsel, Eric A., Wickremasinghe, Ananda R., Van Dijk, Ko Willems, Witte, Daniel R., Yajnik, Chittaranjan S., Yamamoto, Ken, Yamauchi, Toshimasa, Yengo, Loïc, Yoon, Kyungheon, Yu, Canqing, Yuan, Jian-min, Yusuf, Salim, Zhang, Liang, Zheng, Wei, Hayes, M. Geoffrey, Raffel, Leslie J., Igase, Michiya, Ipp, Eli, Redline, Susan, Cho, Yoon Shin, Lind, Lars, Province, Michael A., Hanis, Craig L., Peyser, Patricia A., Ingelsson, Erik, Zonderman, Alan B., Psaty, Bruce M., Wang, Ya-xing, Rotimi, Charles N., Becker, Diane M., Matsuda, Fumihiko, Liu, Yongmei, Zeggini, Eleftheria, Yokota, Mitsuhiro, Rich, Stephen S., Kooperberg, Charles, Pankow, James S., Engert, James C., Chen, Yii-der Ida, Froguel, Philippe, Wilson, James G., Sheu, Wayne H. H., Kardia, Sharon L. R., Wu, Jer-yuarn, Ma, Ronald C. W., Wong, Tien-yin, Groop, Leif, Mook-kanamori, Dennis O., Chandak, Giriraj R., Collins, Francis S., Bharadwaj, Dwaipayan, Paré, Guillaume, Sale, Michèle M., Ahsan, Habibul, Motala, Ayesha A., Shu, Xiao-ou, Park, Kyong-soo, Jukema, J. Wouter, Cruz, Miguel, Mckean-cowdin, Roberta, Grallert, Harald, Cheng, Ching-yu, Bottinger, Erwin P., Dehghan, Abbas, Tai, E-shyong, Dupuis, Josée, Kato, Norihiro, Laakso, Markku, Köttgen, Anna, Koh, Woon-puay, Palmer, Colin N. A., Liu, Simin, Abecasis, Goncalo, Kooner, Jaspal S., Loos, Ruth J. F., North, Kari E., Haiman, Christopher A., Florez, Jose C., Saleheen, Danish, Hansen, Torben, Pedersen, Oluf, Mägi, Reedik, Langenberg, Claudia, Wareham, Nicholas J., Maeda, Shiro, Kadowaki, Takashi, Lee, Juyoung, Millwood, Iona Y., Walters, Robin G., Stefansson, Kari, Myers, Simon R., Ferrer, Jorge, Gaulton, Kyle J., Meigs, James B., Mohlke, Karen L., Gloyn, Anna L., Bowden, Donald W., Below, Jennifer E., Chambers, John C., Sim, Xueling, Boehnke, Michael, Rotter, Jerome I., Mccarthy, Mark I., Morris, Andrew P.

Publikováno v: Nature Genetics, 54(5), 560-572. Nature Publishing Group
Nature Genetics, 54(5), 560-+. NATURE PORTFOLIO
Nature genetics, 54(5), 560-572. Nature Publishing Group
Mahajan, A, Spracklen, C N, Zhang, W, Ng, M C Y, Petty, L E, Kitajima, H, Yu, G Z, Rüeger, S, Speidel, L, Kim, Y J, Horikoshi, M, Mercader, J M, Taliun, D, Moon, S, Kwak, S H, Robertson, N R, Rayner, N W, Loh, M, Kim, B J, Chiou, J, Miguel-Escalada, I, della Briotta Parolo, P, Lin, K, Bragg, F, Preuss, M H, Takeuchi, F, Nano, J, Guo, X, Lamri, A, Nakatochi, M, Scott, R A, Lee, J J, Huerta-Chagoya, A, Graff, M, Chai, J F, Parra, E J, Yao, J, Bielak, L F, Tabara, Y, Grarup, N, Chen, W M, Jensen, R A, Chen, J, Huang, W, Jørgensen, M E, Jørgensen, T, Witte, D R, Zhang, L, Hansen, T, Pedersen, O, FinnGen & eMERGE Consortium 2022, ' Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation ', Nature Genetics, vol. 54, no. 5, pp. 560-572 . https://doi.org/10.1038/s41588-022-01058-3
Mahajan, A, Spracklen, C N, Zhang, W, Ng, M C Y, Petty, L E, Kitajima, H, Yu, G Z, Rüeger, S, Speidel, L, Kim, Y J, Horikoshi, M, Mercader, J M, Taliun, D, Moon, S, Kwak, S-H, Robertson, N R, Rayner, N W, Loh, M, Kim, B-J, Chiou, J, Miguel-Escalada, I, Della Briotta Parolo, P, Lin, K, Bragg, F, Preuss, M H, Takeuchi, F, Nano, J, Guo, X, Lamri, A, Nakatochi, M, Scott, R A, Lee, J-J, Huerta-Chagoya, A, Graff, M, Chai, J-F, Parra, E J, Yao, J, Bielak, L F, Tabara, Y, Hai, Y, Steinthorsdottir, V, Cook, J P, Kals, M, Grarup, N, Schmidt, E M, Pan, I, Sofer, T, Wuttke, M, Sarnowski, C, Gieger, C, Nousome, D, Trompet, S, Long, J, Sun, M, Tong, L, Chen, W-M, Ahmad, M, Noordam, R, Lim, V J Y, Tam, C H T, Joo, Y Y, Chen, C-H, Raffield, L M, Lecoeur, C, Prins, B P, Nicolas, A, Yanek, L R, Chen, G, Jensen, R A, Tajuddin, S, Kabagambe, E K, An, P, Xiang, A H, Choi, H S, Cade, B E, Tan, J, Flanagan, J, Abaitua, F, Adair, L S, Adeyemo, A, Aguilar-Salinas, C A, Akiyama, M, Anand, S S, Bertoni, A, Bian, Z, Bork-Jensen, J, Brandslund, I, Brody, J A, Brummett, C M, Buchanan, T A, Canouil, M, Chan, J C N, Chang, L-C, Chee, M-L, Chen, J, Chen, S-H, Chen, Y-T, Chen, Z, Chuang, L-M, Cushman, M, Das, S K, de Silva, H J, Dedoussis, G, Dimitrov, L, Doumatey, A P, Du, S, Duan, Q, Eckardt, K-U, Emery, L S, Evans, D S, Evans, M K, Fischer, K, Floyd, J S, Ford, I, Fornage, M, Franco, O H, Frayling, T M, Freedman, B I, Fuchsberger, C, Genter, P, Gerstein, H C, Giedraitis, V, González-Villalpando, C, González-Villalpando, M E, Goodarzi, M O, Gordon-Larsen, P, Gorkin, D, Gross, M, Guo, Y, Hackinger, S, Han, S, Hattersley, A T, Herder, C, Howard, A-G, Hsueh, W, Huang, M, Huang, W, Hung, Y-J, Hwang, M Y, Hwu, C-M, Ichihara, S, Ikram, M A, Ingelsson, M, Islam, M T, Isono, M, Jang, H-M, Jasmine, F, Jiang, G, Jonas, J B, Jørgensen, M E, Jørgensen, T, Kamatani, Y, Kandeel, F R, Kasturiratne, A, Katsuya, T, Kaur, V, Kawaguchi, T, Keaton, J M, Kho, A N, Khor, C-C, Kibriya, M G, Kim, D-H, Kohara, K, Kriebel, J, Kronenberg, F, Kuusisto, J, Läll, K, Lange, L A, Lee, M-S, Lee, N R, Leong, A, Li, L, Li, Y, Li-Gao, R, Ligthart, S, Lindgren, C M, Linneberg, A, Liu, C-T, Liu, J, Locke, A E, Louie, T, Luan, J, Luk, A O, Luo, X, Lv, J, Lyssenko, V, Mamakou, V, Mani, K R, Meitinger, T, Metspalu, A, Morris, A D, Nadkarni, G N, Nadler, J L, Nalls, M A, Nayak, U, Nongmaithem, S S, Ntalla, I, Okada, Y, Orozco, L, Patel, S R, Pereira, M A, Peters, A, Pirie, F J, Porneala, B, Prasad, G, Preissl, S, Rasmussen-Torvik, L J, Reiner, A P, Roden, M, Rohde, R, Roll, K, Sabanayagam, C, Sander, M, Sandow, K, Sattar, N, Schönherr, S, Schurmann, C, Shahriar, M, Shi, J, Shin, D M, Shriner, D, Smith, J A, So, W Y, Stančáková, A, Stilp, A M, Strauch, K, Suzuki, K, Takahashi, A, Taylor, K D, Thorand, B, Thorleifsson, G, Thorsteinsdottir, U, Tomlinson, B, Torres, J M, Tsai, F-J, Tuomilehto, J, Tusie-Luna, T, Udler, M S, Valladares-Salgado, A, van Dam, R M, van Klinken, J B, Varma, R, Vujkovic, M, Wacher-Rodarte, N, Wheeler, E, Whitsel, E A, Wickremasinghe, A R, van Dijk, K W, Witte, D R, Yajnik, C S, Yamamoto, K, Yamauchi, T, Yengo, L, Yoon, K, Yu, C, Yuan, J-M, Yusuf, S, Zhang, L, Zheng, W, Raffel, L J, Igase, M, Ipp, E, Redline, S, Cho, Y S, Lind, L, Province, M A, Hanis, C L, Peyser, P A, Ingelsson, E, Zonderman, A B, Psaty, B M, Wang, Y-X, Rotimi, C N, Becker, D M, Matsuda, F, Liu, Y, Zeggini, E, Yokota, M, Rich, S S, Kooperberg, C, Pankow, J S, Engert, J C, Chen, Y-D I, Froguel, P, Wilson, J G, Sheu, W H H, Kardia, S L R, Wu, J-Y, Hayes, M G, Ma, R C W, Wong, T-Y, Groop, L, Mook-Kanamori, D O, Chandak, G R, Collins, F S, Bharadwaj, D, Paré, G, Sale, M M, Ahsan, H, Motala, A A, Shu, X-O, Park, K-S, Jukema, J W, Cruz, M, McKean-Cowdin, R, Grallert, H, Cheng, C-Y, Bottinger, E P, Dehghan, A, Tai, E-S, Dupuis, J, Kato, N, Laakso, M, Köttgen, A, Koh, W-P, Palmer, C N A, Liu, S, Abecasis, G, Kooner, J S, Loos, R J F, North, K E, Haiman, C A, Florez, J C, Saleheen, D, Hansen, T, Pedersen, O, Mägi, R, Langenberg, C, Wareham, N J, Maeda, S, Kadowaki, T, Lee, J, Millwood, I Y, Walters, R G, Stefansson, K, Myers, S R, Ferrer, J, Gaulton, K J, Meigs, J B, Mohlke, K L, Gloyn, A L, Bowden, D W, Below, J E, Chambers, J C, Sim, X, Boehnke, M, Rotter, J I, McCarthy, M I, Morris, A P, FinnGen & eMERGE Consortium 2022, ' Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation ', Nature Genetics, vol. 54, no. 5, pp. 560-572 . https://doi.org/10.1038/s41588-022-01058-3
2022, ' Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation ', Nature Genetics, vol. 54, no. 5, pp. 560-572 . https://doi.org/10.1038/s41588-022-01058-3
Nat. Genet. 54, 560-572 (2022)
Mahajan, A, Spracklen, C N, Zhang, W, Ng, M C Y, Petty, L E, Kitajima, H, Yu, G Z, Rüeger, S, Speidel, L, Kim, Y J, Horikoshi, M, Mercader, J M, Taliun, D, Moon, S, Kwak, S, Robertson, N R, Rayner, N W, Loh, M, Kim, B, Chiou, J, Miguel-escalada, I, Della Briotta Parolo, P, Lin, K, Bragg, F, Preuss, M H, Takeuchi, F, Nano, J, Guo, X, Lamri, A, Nakatochi, M, Scott, R A, Lee, J, Huerta-chagoya, A, Graff, M, Chai, J, Parra, E J, Yao, J, Bielak, L F, Tabara, Y, Hai, Y, Steinthorsdottir, V, Cook, J P, Kals, M, Grarup, N, Schmidt, E M, Pan, I, Sofer, T, Wuttke, M, Sarnowski, C, Gieger, C, Nousome, D, Trompet, S, Long, J, Sun, M, Tong, L, Chen, W, Ahmad, M, Noordam, R, Lim, V J Y, Tam, C H T, Joo, Y Y, Chen, C, Raffield, L M, Lecoeur, C, Prins, B P, Nicolas, A, Yanek, L R, Chen, G, Jensen, R A, Tajuddin, S, Kabagambe, E K, An, P, Xiang, A H, Choi, H S, Cade, B E, Tan, J, Flanagan, J, Abaitua, F, Adair, L S, Adeyemo, A, Aguilar-salinas, C A, Akiyama, M, Anand, S S, Bertoni, A, Bian, Z, Bork-jensen, J, Brandslund, I, Brody, J A, Brummett, C M, Buchanan, T A, Canouil, M, Chan, J C N, Chang, L, Chee, M, Chen, J, Chen, S, Chen, Y, Chen, Z, Chuang, L, Cushman, M, Das, S K, De Silva, H J, Dedoussis, G, Dimitrov, L, Doumatey, A P, Du, S, Duan, Q, Eckardt, K, Emery, L S, Evans, D S, Evans, M K, Fischer, K, Floyd, J S, Ford, I, Fornage, M, Franco, O H, Frayling, T M, Freedman, B I, Fuchsberger, C, Genter, P, Gerstein, H C, Giedraitis, V, González-villalpando, C, González-villalpando, M E, Goodarzi, M O, Gordon-larsen, P, Gorkin, D, Gross, M, Guo, Y, Hackinger, S, Han, S, Hattersley, A T, Herder, C, Howard, A, Hsueh, W, Huang, M, Huang, W, Hung, Y, Hwang, M Y, Hwu, C, Ichihara, S, Ikram, M A, Ingelsson, M, Islam, M T, Isono, M, Jang, H, Jasmine, F, Jiang, G, Jonas, J B, Jørgensen, M E, Jørgensen, T, Kamatani, Y, Kandeel, F R, Kasturiratne, A, Katsuya, T, Kaur, V, Kawaguchi, T, Keaton, J M, Kho, A N, Khor, C, Kibriya, M G, Kim, D, Kohara, K, Kriebel, J, Kronenberg, F, Kuusisto, J, Läll, K, Lange, L A, Lee, M, Lee, N R, Leong, A, Li, L, Li, Y, Li-gao, R, Ligthart, S, Lindgren, C M, Linneberg, A, Liu, C, Liu, J, Locke, A E, Louie, T, Luan, J, Luk, A O, Luo, X, Lv, J, Lyssenko, V, Mamakou, V, Mani, K R, Meitinger, T, Metspalu, A, Morris, A D, Nadkarni, G N, Nadler, J L, Nalls, M A, Nayak, U, Nongmaithem, S S, Ntalla, I, Okada, Y, Orozco, L, Patel, S R, Pereira, M A, Peters, A, Pirie, F J, Porneala, B, Prasad, G, Preissl, S, Rasmussen-torvik, L J, Reiner, A P, Roden, M, Rohde, R, Roll, K, Sabanayagam, C, Sander, M, Sandow, K, Sattar, N, Schönherr, S, Schurmann, C, Shahriar, M, Shi, J, Shin, D M, Shriner, D, Smith, J A, So, W Y, Stančáková, A, Stilp, A M, Strauch, K, Suzuki, K, Takahashi, A, Taylor, K D, Thorand, B, Thorleifsson, G, Thorsteinsdottir, U, Tomlinson, B, Torres, J M, Tsai, F, Tuomilehto, J, Tusie-luna, T, Udler, M S, Valladares-salgado, A, Van Dam, R M, Van Klinken, J B, Varma, R, Vujkovic, M, Wacher-rodarte, N, Wheeler, E, Whitsel, E A, Wickremasinghe, A R, Van Dijk, K W, Witte, D R, Yajnik, C S, Yamamoto, K, Yamauchi, T, Yengo, L, Yoon, K, Yu, C, Yuan, J, Yusuf, S, Zhang, L, Zheng, W, Rüeger, S, Della Briotta Parolo, P, Joo, Y Y, Hayes, M G, Raffel, L J, Igase, M, Ipp, E, Redline, S, Cho, Y S, Lind, L, Province, M A, Hanis, C L, Peyser, P A, Ingelsson, E, Zonderman, A B, Psaty, B M, Wang, Y, Rotimi, C N, Becker, D M, Matsuda, F, Liu, Y, Zeggini, E, Yokota, M, Rich, S S, Kooperberg, C, Pankow, J S, Engert, J C, Chen, Y I, Froguel, P, Wilson, J G, Sheu, W H H, Kardia, S L R, Wu, J, Hayes, M G, Ma, R C W, Wong, T, Groop, L, Mook-kanamori, D O, Chandak, G R, Collins, F S, Bharadwaj, D, Paré, G, Sale, M M, Ahsan, H, Motala, A A, Shu, X, Park, K, Jukema, J W, Cruz, M, Mckean-cowdin, R, Grallert, H, Cheng, C, Bottinger, E P, Dehghan, A, Tai, E, Dupuis, J, Kato, N, Laakso, M, Köttgen, A, Koh, W, Palmer, C N A, Liu, S, Abecasis, G, Kooner, J S, Loos, R J F, North, K E, Haiman, C A, Florez, J C, Saleheen, D, Hansen, T, Pedersen, O, Mägi, R, Langenberg, C, Wareham, N J, Maeda, S, Kadowaki, T, Lee, J, Millwood, I Y, Walters, R G, Stefansson, K, Myers, S R, Ferrer, J, Gaulton, K J, Meigs, J B, Mohlke, K L, Gloyn, A L, Bowden, D W, Below, J E, Chambers, J C, Sim, X, Boehnke, M, Rotter, J I, Mccarthy, M I & Morris, A P 2022, ' Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation ', Nature Genetics, vol. 54, no. 5, pp. 560-572 . https://doi.org/10.1038/s41588-022-01058-3

We assembled an ancestrally diverse collection of genome-wide association studies (GWAS) of type 2 diabetes (T2D) in 180,834 affected individuals and 1,159,055 controls (48.9% non-European descent) through the Diabetes Meta-Analysis of Trans-Ethnic a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3795b8e3c26fbb0c62130d28fea5549e
https://pure.eur.nl/en/publications/3d8c961d-7116-4a9f-bb60-312ae5842805