An Efficient and Simple Entry to N-Substituted beta-Enamino Acid Derivatives from 2-Alkyl-2-oxazolines and 2-Alkyl-2-thiazolines

Autor: Santos Fustero, F. Sanz, M. L. Gonzalez, D. Diaz, Antonio Hidalgo Navarro, Amparo Asensio, de La Torre Mg

Publikováno v: The Journal of organic chemistry. 61(25)

Reaction of azaenolates of 2-alkyl-oxa(thia)zolines 6 with imidoyl chlorides 7 as electrophiles to furnish masked N-substituted beta-enamino acid derivatives 1-2 in 70-90% yield is described. Alternative routes are discussed. Compounds 1-2 generally

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8845832a0bef2c295a9bb3f64e6d514f
https://pubmed.ncbi.nlm.nih.gov/11667864

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Deep immunophenotyping shows altered immune cell subsets in CTLA-4 haploinsufficiency.

Autor: Maiarana J; Department of Pediatrics, Monroe Carell Jr. Children's Hospital at Vanderbilt, Nashville, Tennessee, USA.; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Moncada-Velez M; Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York City, New York, USA., Malbran E; Unidad de Alergia, Asma e Inmunologia Clinica, Buenos Aires, Argentina., Torre MG; Unidad de Alergia, Asma e Inmunologia Clinica, Buenos Aires, Argentina., Elonen C; Department of Medicine, Division of Genetic Medicine, Vanderbilt Institute of Infection, Immunology and Inflammation, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Malbran A; Unidad de Alergia, Asma e Inmunologia Clinica, Buenos Aires, Argentina., Markle JG; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.; Department of Medicine, Division of Genetic Medicine, Vanderbilt Institute of Infection, Immunology and Inflammation, Vanderbilt University Medical Center, Nashville, Tennessee, USA.

Publikováno v: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology [Pediatr Allergy Immunol] 2023 Jul; Vol. 34 (7), pp. e13994.