Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Toros Dincman"'
Autor:
Toros Dincman, Breege V. Howley, Simon Grelet, Alec N. Woosley, Shaun K. Olsen, Bidyut K. Mohanty, Annamarie C. Dalton, Philip H. Howe, George S. Hussey, Sean Bloos
Publikováno v:
Oncogene
FAM3C/Interleukin-like EMT Inducer (ILEI) is an oncogenic member of the FAM3 cytokine family and serves essential roles in both epithelial-mesenchymal transition (EMT) and breast cancer metastasis. ILEI expression levels are regulated through a non-c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fecbb54c681e247b0c54ba4025ef167c
http://europepmc.org/articles/PMC6525020
http://europepmc.org/articles/PMC6525020
Autor:
Breege V. Howley, Bidyut Mohanty, Annamarie Dalton, Simon Grelet, Joseph Karam, Toros Dincman, Philip H. Howe
Publikováno v:
Oncogene. 41(12)
The epithelial to mesenchymal transition (EMT), a process that is aberrantly activated in cancer and facilitates metastasis to distant organs, requires coordinated transcriptional and post-transcriptional control of gene expression. The tumor-suppres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd755c63a6a964dd842fb3f308a6e128
https://pubmed.ncbi.nlm.nih.gov/35102251
https://pubmed.ncbi.nlm.nih.gov/35102251
Autor:
Bidyut K. Mohanty, Breege V. Howley, Buckley J. McCall, Toros Dincman, Annamarie C. Dalton, Ken Noguchi, Philip H. Howe
Publikováno v:
The Journal of Biological Chemistry
Interleukin-like EMT inducer (ILEI, FAM3C) is a secreted factor that contributes to the epithelial-to-mesenchymal transition (EMT), a cell-biological process that confers metastatic properties to a tumor cell. However, very little is known about how
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93916e04c959c611cf49a2157f2694cf
https://doi.org/10.1074/jbc.ra118.003616
https://doi.org/10.1074/jbc.ra118.003616
Autor:
Walter J. Chazin, Philip H. Howe, Annamarie C. Dalton, Joseph Aq Karam, Breege V. Howley, William S. Streitfeld, Simon Grelet, Bidyut K. Mohanty, Lata Balakrishnan, David T. Long, Je-Hyun Yoon, Toros Dincman
Publikováno v:
Life Science Alliance
hnRNP E1 binds polycytosine tracts of DNA and monitors genome integrity.
Heterogeneous nuclear ribonucleoprotein E1 (hnRNP E1) is a tumor suppressor protein that binds site- and structure-specifically to RNA sequences to regulate mRNA stability,
Heterogeneous nuclear ribonucleoprotein E1 (hnRNP E1) is a tumor suppressor protein that binds site- and structure-specifically to RNA sequences to regulate mRNA stability,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aef40295b8da7fd230b94bea199f5d3
https://doi.org/10.26508/lsa.202000995
https://doi.org/10.26508/lsa.202000995
Autor:
Joëlle Roche, Robert M. Gemmill, Anastasios Dimou, Emilie Evanno, Harry A. Drabkin, Toros Dincman
Publikováno v:
Cancer Treatment and Research Communications. 12:40-48
Cancer is a disease of dysregulated growth and differentiation, along with the ability of the cancer cell to invade, metastasize and escape immune surveillance. Altered transcription factor activity from mutations, gene fusions, copy number alteratio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::925e21b5df9d1b357d1ea8be49eb9db6
https://doi.org/10.1016/j.ctarc.2017.06.003
https://doi.org/10.1016/j.ctarc.2017.06.003
Autor:
Amy Sion, Thomas E. Keane, Jennifer Mikoll, Hong Li, Harry S. Clarke, Theodore Stewart Gourdin, Michael B. Lilly, Toros Dincman, Robert L. Grubb, David T. Marshall, Arif Hussain, David Sellman, Stephen J. Savage, Pooja Patel
Publikováno v:
Journal of Clinical Oncology. 39:116-116
116 Background: Randomized trials have demonstrated a survival advantage to administering docetaxel (D) shortly after initiation of androgen deprivation therapy (ADT) in men with newly diagnosed hormone sensitive metastatic prostate cancer (hsMPC). C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::763519e3be07336272395ab15ed6bd3e
https://doi.org/10.1200/jco.2021.39.6_suppl.116
https://doi.org/10.1200/jco.2021.39.6_suppl.116
Autor:
Vittorio Gallo, Toros Dincman, Michal Hetman, Jason E. Beare, Sujata Saraswat Ohri, Scott R. Whittemore
Publikováno v:
International Journal of Developmental Neuroscience. 54:53-61
Histone deacetylase (HDAC) inhibition mediated by small molecule HDAC inhibitors (HDACi) has demonstrated divergent effects including toxicity towards transformed cell lines, neuroprotection in neurological disease models, and inhibition of oligodend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ccd364f53e7801eeb9017e9f5d74607
https://doi.org/10.1016/j.ijdevneu.2016.08.006
https://doi.org/10.1016/j.ijdevneu.2016.08.006
Autor:
Leylah Drusbosky, Toros Dincman, Philip H. Howe, Antonio Giordano, Hong Li, Michael B. Lilly, Theodore Stewart Gourdin
Publikováno v:
Journal of Clinical Oncology. 38:e17594-e17594
e17594 Background: mPC is a dynamic disease that confers a poor prognosis- particularly in the metastatic castration-resistant prostate cancer (mCRPC) setting. Analysis of ctDNA provides an opportunity to identify and monitor somatic alterations (SAs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00069607d92fb0b4f8ece1c974f18648
https://doi.org/10.1200/jco.2020.38.15_suppl.e17594
https://doi.org/10.1200/jco.2020.38.15_suppl.e17594
Autor:
Richard Song, Bernard S. Strauss, Kemba Kelly, Toros Dincman, Damian C. Ekiert, Theresa Biesieda
Publikováno v:
Journal of Bacteriology. 186:2147-2155
Cells of the Escherichia coli dnaE (Ts) dnaE74 and dnaE486 mutants die after 4 h of incubation at 40°C in Luria-Bertani medium. Cell death is preceded by elongation, is inhibited by chloramphenicol, tetracycline, or rifampin, and is dependent on cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1b109fb2a5865ec7c950d8d65578973
https://doi.org/10.1128/jb.186.7.2147-2155.2004
https://doi.org/10.1128/jb.186.7.2147-2155.2004
Publikováno v:
Journal of neuroscience methods. 209(1)
The reliable isolation of primary oligodendrocyte progenitors cells (OPCs) holds promise as both a research tool and putative therapy for the study and treatment of central nervous system (CNS) disease and trauma. Stringently characterized primary mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cee6a610ff645f8441db47facfdef5c
https://pubmed.ncbi.nlm.nih.gov/22743801
https://pubmed.ncbi.nlm.nih.gov/22743801