Výsledky vyhledávání - "Tormod B. Krüger"

Akademický článek

Alendronate and omeprazole in combination reduce angiogenic and growth signals from osteoblasts

Autor: Tormod B. Krüger, Bente B. Herlofson, Aina M. Lian, Unni Syversen, Janne E. Reseland

Publikováno v: Bone Reports, Vol 14, Iss , Pp 100750- (2021)

Objective: Due to gastrointestinal side effects of oral bisphosphonates (BPs), proton pump inhibitors (PPIs) are often prescribed. PPIs may enhance the risk of osteonecrosis of the jaw, a rare side effect of BPs. Therefore, the objective of this stud

Externí odkaz: https://doaj.org/article/1dfb1f2c47a04c90a2103f324a2d4f15

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Targeting a therapeutically relevant concentration of alendronate for in vitro studies on osteoblasts

Autor: Tormod B. Krüger, Unni Syversen, Bente B. Herlofson, Aina M. Lian, Janne E. Reseland

Publikováno v: Acta Odontologica Scandinavica

Objective Bisphosphonates like alendronate mainly exert their effects on osteoclasts. However, osteoblasts are also affected, but exposed to a much lower concentration in vivo than the osteoclasts. Given that the effects are dose-dependent, the inten

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6cd285d4277e7fa48bce6d28348982d
https://pubmed.ncbi.nlm.nih.gov/35605138

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Alendronate and omeprazole in combination reduce angiogenic and growth signals from osteoblasts

Autor: Janne E. Reseland, Bente Brokstad Herlofson, Aina-Mari Lian, Unni Syversen, Tormod B Krüger

Publikováno v: Bone Reports
14:100750
Bone Reports, Vol 14, Iss, Pp 100750-(2021)

Objective Due to gastrointestinal side effects of oral bisphosphonates (BPs), proton pump inhibitors (PPIs) are often prescribed. PPIs may enhance the risk of osteonecrosis of the jaw, a rare side effect of BPs. Therefore, the objective of this study

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::922c114098734daf561159deb89e8bd1
http://europepmc.org/articles/PMC7856318

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Bisphosphonate-related osteonecrosis of the jaw in four Nordic countries and an indication of under-reporting

Autor: Bente Brokstad Herlofson, Tormod B Krüger, Mohammad N Sharikabad

Publikováno v: Acta Odontologica Scandinavica. 71:1386-1390

To assess reported cases of bisphosphonate-related osteonecrosis of the jaw (BONJ) to Medicines Agencies (MAs) in four Nordic countries and to compare the Norwegian MA data with BONJ cases retrieved through an e-mail survey to Oral and Maxillofacial

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56822a4fd1c4709cd480326b90d14d93
https://doi.org/10.3109/00016357.2013.764007

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Alendronate alters osteoblast activities

Autor: Tormod B Krüger, Maria A. Landin, Janne E. Reseland, Bente Brokstad Herlofson

Publikováno v: Acta odontologica Scandinavica. 74(7)

Due to accumulation in the bone matrix and a half-life of at least 10 years, it is important to understand the cellular impact of bisphosphonates (BPs). This study assessed the effects of alendronate (ALN) on human primary osteoblasts.Osteoblasts wer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::163b9c8209d9739ed695867659334c53
https://pubmed.ncbi.nlm.nih.gov/27546224

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