Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Tormi Reinson"'
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0131675 (2015)
Viruses manipulate the cell cycle of the host cell to optimize conditions for more efficient viral genome replication. One strategy utilized by DNA viruses is to replicate their genomes non-concurrently with the host genome; in this case, the viral g
Externí odkaz:
https://doaj.org/article/94dc6ad244e24f04b7755a3515b314ef
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0135770 (2015)
Stable maintenance replication is characteristic of the latency phase of HPV infection, during which the viral genomes are actively maintained as extrachromosomal genetic elements in infected proliferating basal keratinocytes. Active replication in t
Externí odkaz:
https://doaj.org/article/6598bb90180b420d9053d04ab6a8af6d
Autor:
Tormi Reinson, Mihkel Allik, Mart Ustav, Ene Ustav, Meelis Kadaja, Mart Toots, Regina Pipitch
Publikováno v:
Journal of virology. 87(2)
We have previously demonstrated that the human papillomavirus (HPV) genome replicates effectively in U2OS cells after transfection using electroporation. The transient extrachromosomal replication, stable maintenance, and late amplification of the vi
Autor:
Helen Isok-Paas, Kristiina Salk, Triin Laos, Tormi Reinson, Mart Ustav, Ene Ustav, Jelizaveta Geimanen, Marit Orav, Regina Pipitch
Publikováno v:
Journal of virology. 85(7)
We found that recircularized high-risk (type 16 and 18) and low-risk mucosal (type 6b and 11) and cutaneous (type 5 and 8) human papillomavirus (HPV) genomes replicate readily when delivered into U2OS cells by electroporation. The replication efficie