Serum protein signatures differentiating autoimmune pancreatitis versus pancreatic cancer.

Autor: Klaus Felix, Oliver Hauck, Stefan Fritz, Ulf Hinz, Martina Schnölzer, Tore Kempf, Uwe Warnken, Angelika Michel, Michael Pawlita, Jens Werner

Publikováno v: PLoS ONE, Vol 8, Iss 12, p e82755 (2013)

Autoimmune pancreatitis (AIP) is defined by characteristic lymphoplasmacytic infiltrate, ductal strictures and a pancreatic enlargement or mass that can mimic pancreatic cancer (PaCa). The distinction between this benign disease and pancreatic cancer

Externí odkaz: https://doaj.org/article/88f0dae11af8474ea451080c0c5e0f2a

Supplementary Figure Legends 1-4 from Costimulatory Protein 4IgB7H3 Drives the Malignant Phenotype of Glioblastoma by Mediating Immune Escape and Invasiveness

Autor: Wolfgang Wick, Michael Platten, Michael Weller, Ruxandra Tudoran, Martina Schnölzer, Uwe Warnken, Tore Kempf, Ann-Catherine Klein, Felix Sahm, Philipp-Niclas Pfenning, Dieter Lemke

PDF file - 64K

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a2f59844981701a71c60bfc5b1eda32
https://doi.org/10.1158/1078-0432.22446360.v1

Data from Costimulatory Protein 4IgB7H3 Drives the Malignant Phenotype of Glioblastoma by Mediating Immune Escape and Invasiveness

Autor: Wolfgang Wick, Michael Platten, Michael Weller, Ruxandra Tudoran, Martina Schnölzer, Uwe Warnken, Tore Kempf, Ann-Catherine Klein, Felix Sahm, Philipp-Niclas Pfenning, Dieter Lemke

Purpose: Recent work points out a role of B7H3, a member of the B7-family of costimulatory proteins, in conveying immunosuppression and enforced invasiveness in a variety of tumor entities. Glioblastoma is armed with effective immunosuppressive prope

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::195db7e3b1f8ebc71e605f3b5eed7c43
https://doi.org/10.1158/1078-0432.c.6520728

Drosophila Spag Is the Homolog of RNA Polymerase II-associated Protein 3 (RPAP3) and Recruits the Heat Shock Proteins 70 and 90 (Hsp70 and Hsp90) during the Assembly of Cellular Machineries

Autor: Ioannis Iliopoulos, Nour El Houda Benbahouche, Tore Kempf, Istvan Török, Philippe Meyer, Robert Farkaš, Edouard Bertrand, István Kiss, Julien Henri, Bernard M. Mechler, Bérengère Pradet-Balade, Andrey V. Kajava, Joachim Marhold, Martina Schnölzer

Publikováno v: Journal of Biological Chemistry
Journal of Biological Chemistry, 2014, 289 (9), pp.6236--47. ⟨10.1074/jbc.M113.499608⟩
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2014, 289 (9), pp.6236--47. ⟨10.1074/jbc.M113.499608⟩

The R2TP is a recently identified Hsp90 co-chaperone, composed of four proteins as follows: Pih1D1, RPAP3, and the AAA(+)-ATPases RUVBL1 and RUVBL2. In mammals, the R2TP is involved in the biogenesis of cellular machineries such as RNA polymerases, s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96e0637b89bada28a508ab1d8fe16075
https://doi.org/10.1074/jbc.m113.499608

Identification of Novel Serum Autoantibodies for Differential Diagnosis of Autoimmune Pancreatitis and Pancreatic Ductal Adenocarcinoma

Autor: Stefan Fritz, Frank Bergmann, Uwe Warnken, Kathrin Schneider, Klaus Felix, Oliver Hauck, Martina Schnölzer, Tore Kempf, Jens Werner

Publikováno v: Pancreas. 45(9)

Objectives: The lack of specific biochemical markers is a major drawback for the diagnosis of autoimmune pancreatitis (AIP). The aims were to characterize the autoantibody profiles in AIP and pancreatic ductal adenocarcinoma (PDAC) and to identify ci

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a86f83da3c9de84797d3ac47fd9093d
https://pubmed.ncbi.nlm.nih.gov/27623556