Use of Arc expression as a molecular marker of increased postsynaptic 5-HT function after SSRI/5-HT1A receptor antagonist co-administration

Autor: Castro, E, Tordera, RM, Hughes, ZA, Pei, Q, Sharp, T

An increase in central postsynaptic 5-hydroxytryptamine (5-HT) function activates expression of activity-related cytoskeletal protein (Arc). Here, Arc expression was used to test whether, in rats, co-administration of a 5-HT re-uptake inhibitor (paro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::b6e8ca587cde00fe90afdef189e96d94
https://doi.org/10.1046/j.1471-4159.2003.01782.x

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SIRT2 Inhibition Rescues Neurodegenerative Pathology but Increases Systemic Inflammation in a Transgenic Mouse Model of Alzheimer's Disease.

Autor: Sola-Sevilla N; Department of Pharmacology and Toxicology, University of Navarra, Navarra Institute for Health Research (IdiSNA), C/ Irunlarrea, 1, 31008, Pamplona, Spain., Mesa-Lombardo A; Department of Pharmacology and Toxicology, University of Navarra, Navarra Institute for Health Research (IdiSNA), C/ Irunlarrea, 1, 31008, Pamplona, Spain.; Department of Anatomy, Histology and Neurosciences, Medical School, Autonoma University of Madrid, 28029, Madrid, Spain., Aleixo M; Department of Pharmacology and Toxicology, University of Navarra, Navarra Institute for Health Research (IdiSNA), C/ Irunlarrea, 1, 31008, Pamplona, Spain., Expósito S; Laboratory of Neurophysiology and Synaptic Plasticity, Instituto Cajal, Consejo Superior de Investigaciones Científicas, Madrid, Spain., Diaz-Perdigón T; Department of Pharmacology and Toxicology, University of Navarra, Navarra Institute for Health Research (IdiSNA), C/ Irunlarrea, 1, 31008, Pamplona, Spain., Azqueta A; Department of Pharmacology and Toxicology, University of Navarra, Navarra Institute for Health Research (IdiSNA), C/ Irunlarrea, 1, 31008, Pamplona, Spain., Zamani F; SANKEN, Osaka University, Ibaraki, Osaka, Japan., Suzuki T; SANKEN, Osaka University, Ibaraki, Osaka, Japan., Maioli S; Department of Neurobiology, Care Sciences and Society, Division of Neurogeriatrics, Center for Alzheimer Research, Karolinska Institutet, Stockholm, Sweden., Eroli F; Department of Neurobiology, Care Sciences and Society, Division of Neurogeriatrics, Center for Alzheimer Research, Karolinska Institutet, Stockholm, Sweden., Matton A; Department of Neurobiology, Care Sciences and Society, Division of Neurogeriatrics, Center for Alzheimer Research, Karolinska Institutet, Stockholm, Sweden., Ramírez MJ; Department of Pharmacology and Toxicology, University of Navarra, Navarra Institute for Health Research (IdiSNA), C/ Irunlarrea, 1, 31008, Pamplona, Spain., Solas M; Department of Pharmacology and Toxicology, University of Navarra, Navarra Institute for Health Research (IdiSNA), C/ Irunlarrea, 1, 31008, Pamplona, Spain., Tordera RM; Department of Pharmacology and Toxicology, University of Navarra, Navarra Institute for Health Research (IdiSNA), C/ Irunlarrea, 1, 31008, Pamplona, Spain., Martín ED; Laboratory of Neurophysiology and Synaptic Plasticity, Instituto Cajal, Consejo Superior de Investigaciones Científicas, Madrid, Spain., Puerta E; Department of Pharmacology and Toxicology, University of Navarra, Navarra Institute for Health Research (IdiSNA), C/ Irunlarrea, 1, 31008, Pamplona, Spain. epuerta@unav.es.

Publikováno v: Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology [J Neuroimmune Pharmacol] 2023 Sep; Vol. 18 (3), pp. 529-550. Date of Electronic Publication: 2023 Sep 12.

Understanding the Potential Role of Sirtuin 2 on Aging: Consequences of SIRT2.3 Overexpression in Senescence.

Autor: Sola-Sevilla N; Pharmacology and Toxicology Department, Faculty of Pharmacy, University of Navarra, Navarra Institute for Health Research (IdiSNA), 31008 Pamplona, Spain., Ricobaraza A; Gene Therapy Program CIMA, University of Navarra, Navarra Institute for Health Research (IdiSNA), 31008 Pamplona, Spain., Hernandez-Alcoceba R; Gene Therapy Program CIMA, University of Navarra, Navarra Institute for Health Research (IdiSNA), 31008 Pamplona, Spain., Aymerich MS; Departamento de Bioquímica y Genética, Facultad de Ciencias, Universidad de Navarra, 31008 Pamplona, Spain.; Neuroscience Program CIMA, University of Navarra, Navarra Institute for Health Research (IdiSNA), 31008 Pamplona, Spain., Tordera RM; Pharmacology and Toxicology Department, Faculty of Pharmacy, University of Navarra, Navarra Institute for Health Research (IdiSNA), 31008 Pamplona, Spain., Puerta E; Pharmacology and Toxicology Department, Faculty of Pharmacy, University of Navarra, Navarra Institute for Health Research (IdiSNA), 31008 Pamplona, Spain.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2021 Mar 18; Vol. 22 (6). Date of Electronic Publication: 2021 Mar 18.

Role of Histone Deacetylases in Monocyte Function in Health and Chronic Inflammatory Diseases.

Autor: Tordera RM; Department of Pharmacology and Toxicology, Universidad de Navarra, School of Pharmacy and Nutrition, Pamplona, Spain. rtordera@unav.es., Cortés-Erice M; Department of Pharmacology and Toxicology, Universidad de Navarra, School of Pharmacy and Nutrition, Pamplona, Spain.

Publikováno v: Reviews of physiology, biochemistry and pharmacology [Rev Physiol Biochem Pharmacol] 2021; Vol. 180, pp. 1-47.