Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Torbjörn Egelrud"'
Autor:
Pablo Forte, Jukka Mäenpää, Robert Palmér, Alexandra Jauhiainen, Susanne Prothon, James Root, Philip Gardiner, Muir Russell, Ligia Chialda, Bengt Larsson, Torbjörn Egelrud, Kristina Stenvall, John Mo
Publikováno v:
Clinical Pharmacology and Therapeutics
Neutrophil serine proteases (NSPs), such as neutrophil elastase (NE), are activated by dipeptidyl peptidase 1 (DPP1) during neutrophil maturation. High NSP levels can be detrimental, particularly in lung tissue, and inhibition of NSPs is therefore an
Autor:
Dirk Roosterman, Kristina Stefansson, Georgeta Bocheva, Torbjörn Egelrud, Maria Brattsand, Cordula Kempkes, Martin Steinhoff
Publikováno v:
Journal of Investigative Dermatology. 128(1):18-25
Proteinase-activated receptor-2 (PAR2) is a seven transmembrane spanning, G-protein-coupled receptor, present on the membrane of many cell types including keratinocytes. In skin, PAR2 is suggested to play a regulatory role during inflammation, epider
Autor:
O. Bäck, Torbjörn Egelrud
Publikováno v:
British Journal of Dermatology. 112:539-545
A mouse model for assessment of the anti-inflammatory effect of topical glucocorticoids is described. Mice, sensitized to picryl chloride, had both ears painted with the sensitizer followed 2 hours later by the application of the topical steroid to o
Autor:
Annelii Ny, Torbjörn Egelrud
Publikováno v:
Acta Dermato-Venereologica. 84:18-22
Stratum corneum chymotryptic enzyme (SCCE; also known as kallikrein 7) is a serine protease that may have an important role in the skin desquamation process. We have recently described transgenic mice overexpressing human SCCE in suprabasal epidermal
Autor:
Annelii Ny, Torbjörn Egelrud
Publikováno v:
Acta Dermato-Venereologica. 83:322-327
Stratum corneum chymotryptic enzyme (SCCE; also known as kallikrein 7) is a serine protease that is preferentially expressed in cornifying epithelia and possibly involved in the desquamation process. We have recently described transgenic mice over-ex
Autor:
Michel Simon, Guy Serre, Torbjörn Egelrud, Dominique Bernard, Nathalie Jonca, Marina Guerrin, Rainer Schmidt, Cécile Caubet, Marek Haftek
Publikováno v:
Journal of Biological Chemistry. 276:20292-20299
Corneodesmosin is a putative adhesion glycoprotein located in the extracellular part of the desmosomes in the upper layers of the epidermis. Synthesized by granular keratinocytes as a 52–56-kDa protein, corneodesmosin is progressively proteolysed d
Autor:
Shigetaka Yoshida, Harry G. Rittenhouse, H Wain, Eleftherios P. Diamandis, Hans Lilja, Torbjörn Egelrud, Peter S. Nelson, Judith A. Clements, Sheila P. Little, George M. Yousef, Sadao Shiosaka, Ulf-Håkan Stenman, Linda K. Ashworth
Publikováno v:
Clinical Chemistry. 46:1855-1858
The human kallikrein gene family is important to the discipline of clinical chemistry because it contains genes that encode for valuable cancer biomarkers, including the best tumor marker available today, prostate-specific antigen (PSA). Despite repo
Autor:
Torbjörn Egelrud, Maria Brattsand
Publikováno v:
Journal of Biological Chemistry. 274:30033-30040
A new human 33-kDa serine protease was purified from human epidermis, and its cDNA was cloned from a keratinocyte library, from mRNA from a human keratinocyte line (HaCat) and from mRNA from human skin. Polyclonal antibodies specific for the new prot
Autor:
Torbjörn Egelrud, Elisabeth Ekholm
Publikováno v:
Archives of Dermatological Research. 291:195-200
Stratum corneum chymotryptic enzyme (SCCE) is a serine protease which may function in the turnover of the stratum corneum by means of degradation of intercellular adhesive structures between corneocytes. It is also potentially an epidermal activating
Autor:
E Ekholm, Torbjörn Egelrud
Publikováno v:
British Journal of Dermatology. 139:585-590
At sites with a continuous formation of cornified epithelia, there is need for continuous cell shedding in order to maintain normal anatomy. Stratum corneum chymotryptic enzyme (SCCE) has been suggested to mediate this process by degrading intercellu