Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Torben Ruhwedel"'
Autor:
Ludwik Gąsiorowski, Isabel Lucia Dittmann, Jeremias N. Brand, Torben Ruhwedel, Wiebke Möbius, Bernhard Egger, Jochen C. Rink
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-19 (2023)
Abstract Background Unlike most free-living platyhelminths, catenulids, the sister group to all remaining flatworms, do not have eyes. Instead, the most prominent sensory structures in their heads are statocysts or sensory pits. The latter, found in
Externí odkaz:
https://doaj.org/article/8bb1665bc53141d1ae44c1c81afdf4fb
Autor:
Martin Meschkat, Anna M. Steyer, Marie-Theres Weil, Kathrin Kusch, Olaf Jahn, Lars Piepkorn, Paola Agüi-Gonzalez, Nhu Thi Ngoc Phan, Torben Ruhwedel, Boguslawa Sadowski, Silvio O. Rizzoli, Hauke B. Werner, Hannelore Ehrenreich, Klaus-Armin Nave, Wiebke Möbius
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Myelin is formed of proteins of long half-lives. The mechanisms of renewal of such a stable structure are unclear. Here, the authors show that myelin integrity requires continuous myelin synthesis at the inner tongue, contributing to the maintenance
Externí odkaz:
https://doaj.org/article/287e7feee643483fbef3a7725df08a2f
Autor:
Kerstin Menck, Saskia Heinrichs, Darius Wlochowitz, Maren Sitte, Helen Noeding, Andreas Janshoff, Hannes Treiber, Torben Ruhwedel, Bawarjan Schatlo, Christian von der Brelie, Stefan Wiemann, Tobias Pukrop, Tim Beißbarth, Claudia Binder, Annalen Bleckmann
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-18 (2021)
Abstract Background Breast cancer has been associated with activation of the WNT signaling pathway, although no driver mutations in WNT genes have been found yet. Instead, a high expression of the alternative WNT receptor ROR2 was observed, in partic
Externí odkaz:
https://doaj.org/article/d0a5a0c967764391a19be071ba9a9dca
Autor:
Ladina Hösli, Noemi Binini, Kim David Ferrari, Laetitia Thieren, Zoe J. Looser, Marc Zuend, Henri S. Zanker, Stewart Berry, Martin Holub, Wiebke Möbius, Torben Ruhwedel, Klaus-Armin Nave, Christian Giaume, Bruno Weber, Aiman S. Saab
Publikováno v:
Cell Reports, Vol 38, Iss 10, Pp 110484- (2022)
Summary: The mechanisms by which astrocytes modulate neural homeostasis, synaptic plasticity, and memory are still poorly explored. Astrocytes form large intercellular networks by gap junction coupling, mainly composed of two gap junction channel pro
Externí odkaz:
https://doaj.org/article/6141a1541b9a4958a50d6e78433e4ecb
Autor:
Tobias J Buscham, Maria A Eichel-Vogel, Anna M Steyer, Olaf Jahn, Nicola Strenzke, Rakshit Dardawal, Tor R Memhave, Sophie B Siems, Christina Müller, Martin Meschkat, Ting Sun, Torben Ruhwedel, Wiebke Möbius, Eva-Maria Krämer-Albers, Susann Boretius, Klaus-Armin Nave, Hauke B Werner
Publikováno v:
eLife, Vol 11 (2022)
Oligodendrocytes facilitate rapid impulse propagation along the axons they myelinate and support their long-term integrity. However, the functional relevance of many myelin proteins has remained unknown. Here, we find that expression of the tetraspan
Externí odkaz:
https://doaj.org/article/f7b1fb656ccc4da5be331128cb894c52
Autor:
Melanie Lohrberg, Anne Winkler, Jonas Franz, Franziska van der Meer, Torben Ruhwedel, Nikoloz Sirmpilatze, Rakshit Dadarwal, Ronja Handwerker, Daniel Esser, Kerstin Wiegand, Christian Hagel, Andreas Gocht, Fatima Barbara König, Susann Boretius, Wiebke Möbius, Christine Stadelmann, Alonso Barrantes-Freer
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-24 (2020)
Abstract Demyelinated lesions in human pons observed after osmotic shifts in serum have been referred to as central pontine myelinolysis (CPM). Astrocytic damage, which is prominent in neuroinflammatory diseases like neuromyelitis optica (NMO) and mu
Externí odkaz:
https://doaj.org/article/918549fd508a43c99de49fff73f22fe0
Autor:
Sharlen Moore, Martin Meschkat, Torben Ruhwedel, Andrea Trevisiol, Iva D. Tzvetanova, Arne Battefeld, Kathrin Kusch, Maarten H. P. Kole, Nicola Strenzke, Wiebke Möbius, Livia de Hoz, Klaus-Armin Nave
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Oligodendrocytes myelinate and metabolically support axons. The role of myelination in information processing beyond regulation of conduction velocity is unclear. Here, the authors show that myelination contributes to sustained stimulus perception in
Externí odkaz:
https://doaj.org/article/a09d02aa6f5a496d8ea875c4ea276d34
Autor:
Anastasia Dagkonaki, Maria Avloniti, Maria Evangelidou, Irini Papazian, Ioannis Kanistras, Vivian Tseveleki, Fotis Lampros, Theodore Tselios, Lise Torp Jensen, Wiebke Möbius, Torben Ruhwedel, Maria-Eleni Androutsou, John Matsoukas, Maria Anagnostouli, Hans Lassmann, Lesley Probert
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
CNS autoantigens conjugated to oxidized mannan (OM) induce antigen-specific T cell tolerance and protect mice against autoimmune encephalomyelitis (EAE). To investigate whether OM-peptides treat EAE initiated by human MHC class II molecules, we admin
Externí odkaz:
https://doaj.org/article/01e6e4ce64414d3fbec5f23cf0834a95
Autor:
Stefan A. Berghoff, Tim Düking, Lena Spieth, Jan Winchenbach, Sina K. Stumpf, Nina Gerndt, Kathrin Kusch, Torben Ruhwedel, Wiebke Möbius, Gesine Saher
Publikováno v:
Acta Neuropathologica Communications, Vol 5, Iss 1, Pp 1-13 (2017)
Abstract In neuroinflammatory disorders such as multiple sclerosis, the physiological function of the blood-brain barrier (BBB) is perturbed, particularly in demyelinating lesions and supposedly secondary to acute demyelinating pathology. Using the t
Externí odkaz:
https://doaj.org/article/d7f11a965962441290665d029f07d603
Autor:
Stefan A. Berghoff, Nina Gerndt, Jan Winchenbach, Sina K. Stumpf, Leon Hosang, Francesca Odoardi, Torben Ruhwedel, Carolin Böhler, Benoit Barrette, Ruth Stassart, David Liebetanz, Payam Dibaj, Wiebke Möbius, Julia M. Edgar, Gesine Saher
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Cholesterol is important for axonal myelination during development. Here the authors show that cholesterol levels are reduced in a cuprizone mouse model of multiple sclerosis and that dietary cholesterol supplementation enhances remyelination and rec
Externí odkaz:
https://doaj.org/article/3ee45ebdd5304a2ead8ae8d4b159b5bf