Výsledky vyhledávání - "Torben Reichardt"

Illuminating a Dark Kinase: Structure-Guided Design, Synthesis, and Evaluation of a Potent Nek1 Inhibitor and Its Effects on the Embryonic Zebrafish Pronephros

Autor: Yung-Hsin Shih, Ulrich Pehl, Georg Baumann, Boris Schmidt, Torben Reichardt, Mirco Dickhaut, Kevin Böhm, Tobias Meckel, Johannes Pilakowski

Publikováno v: Journal of Medicinal Chemistry. 65:1265-1282

NIMA-related kinase 1 (Nek1) has lately garnered attention for its widespread function in ciliogenesis, apoptosis, and the DNA-damage response. Despite its involvement in various diseases and its potential as a cancer drug target, no directed medicin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f4d87909737473edf3bddc13d231573
https://doi.org/10.1021/acs.jmedchem.0c02118

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