Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Torben Kimhofer"'
Autor:
Natalja Kurbatova, Manik Garg, Luke Whiley, Elena Chekmeneva, Beatriz Jiménez, María Gómez-Romero, Jake Pearce, Torben Kimhofer, Ellie D’Hondt, Hilkka Soininen, Iwona Kłoszewska, Patrizia Mecocci, Magda Tsolaki, Bruno Vellas, Dag Aarsland, Alejo Nevado-Holgado, Benjamine Liu, Stuart Snowden, Petroula Proitsi, Nicholas J. Ashton, Abdul Hye, Cristina Legido-Quigley, Matthew R. Lewis, Jeremy K. Nicholson, Elaine Holmes, Alvis Brazma, Simon Lovestone
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-17 (2020)
Abstract Finding early disease markers using non-invasive and widely available methods is essential to develop a successful therapy for Alzheimer’s Disease. Few studies to date have examined urine, the most readily available biofluid. Here we repor
Externí odkaz:
https://doaj.org/article/1bd85f619d574055ba7c1fb49956bdea
Autor:
Muhammad Saeed Ahmad, Torben Kimhofer, Sultan Ahmad, Mohammed Nabil AlAma, Hala Hisham Mosli, Salwa Ibrahim Hindawi, Dennis O Mook-Kanamori, Katarína Šebeková, Zoheir Abdullah Damanhouri, Elaine Holmes
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0185175 (2017)
Skin auto fluorescence (SAF) is used as a proxy for the accumulation of advanced glycation end products (AGEs) and has been proposed to stratify patients into cardiovascular disease (CVD) and diabetes mellitus (DM) risk groups. This study evaluates t
Externí odkaz:
https://doaj.org/article/26ebaaf2e91842be979a92feca63579f
Autor:
Reika Masuda, Samantha Lodge, Luke Whiley, Nicola Gray, Nathan Lawler, Philipp Nitschke, Sze-How Bong, Torben Kimhofer, Ruey Leng Loo, Berin Boughton, Annie X. Zeng, Drew Hall, Hartmut Schaefer, Manfred Spraul, Girish Dwivedi, Bu B. Yeap, Tammo Diercks, Ganeko Bernardo-Seisdedos, José M. Mato, John C. Lindon, Elaine Holmes, Oscar Millet, Julien Wist, Jeremy K. Nicholson
Publikováno v:
Analytical Chemistry. 94:4426-4436
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6fb39f0415413e8b7dd12dc1c0a5eab4
https://doi.org/10.1021/acs.analchem.1c05389
https://doi.org/10.1021/acs.analchem.1c05389
Autor:
Sze-How Bong, Hartmut Schaefer, Torben Kimhofer, Rubén Gil-Redondo, Maider Bizkarguenaga, Oscar Millet, Philipp Nitschke, Jeremy K. Nicholson, Chiara Bruzzone, Julien Wist, José M. Mato, Reika Masuda, Elaine Holmes, Nieves Embade, Drew Hall, Manfred Spraul, Samantha Lodge, Ruey Leng Loo
Publikováno v:
Journal of Proteome Research. 20:4139-4152
Quantitative plasma lipoprotein and metabolite profiles were measured on an autonomous community of the Basque Country (Spain) cohort consisting of hospitalized COVID-19 patients (n = 72) and a matched control group (n = 75) and a Western Australian
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8efc2e430d431418effb0397977f58c
https://doi.org/10.1021/acs.jproteome.1c00458
https://doi.org/10.1021/acs.jproteome.1c00458
Autor:
Sven Pettersson, Ruey Leng Loo, Monique Ryan, Manfred Spraul, Sze-How Bong, Dale W. Edgar, Philipp Nitschke, Rongchang Yang, Sofina Begum, Samantha Lodge, Torben Kimhofer, Sung Tong Chin, Nathan G. Lawler, Toby Richards, Reika Masuda, Julien Wist, John C. Lindon, Luke Whiley, Drew Hall, Hartmut Schaefer, Berin A. Boughton, Aude-Claire Morillon, Bu B. Yeap, Elaine Holmes, Nicola Gray, Jeremy K. Nicholson
Publikováno v:
Journal of Proteome Research
We present a multivariate metabotyping approach to assess the functional recovery of nonhospitalized COVID-19 patients and the possible biochemical sequelae of "Post-Acute COVID-19 Syndrome", colloquially known as long-COVID. Blood samples were taken
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::382d3a13979d85e6ee3a8a48b02d3ced
https://doi.org/10.1021/acs.jproteome.1c00224
https://doi.org/10.1021/acs.jproteome.1c00224
Autor:
Sofina Begum, Samantha Lodge, Chris Smith, Nicola Gray, Kenneth G. C. Smith, Toby Richards, Jeremy K. Nicholson, Ruey Leng Loo, Luke Whiley, Elaine Holmes, Philipp Nitschke, Bu B. Yeap, David Morrison, Nathan G. Lawler, Torben Kimhofer, Sze-How Bong
Publikováno v:
Journal of Proteome Research
The metabolic effects of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection on human blood plasma were characterized using multi-platform metabolic phenotyping with Nuclear Magnetic Resonance (NMR) spectroscopy and liquid chromato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8422129ca9ad0362d5e7975b25e1b74f
https://doi.org/10.1021/acs.jproteome.0c00519
https://doi.org/10.1021/acs.jproteome.0c00519
Autor:
Robin D, Abeles, Benjamin H, Mullish, Roberta, Forlano, Torben, Kimhofer, Maciej, Adler, Alexandros, Tzallas, Nikolaos, Giannakeas, Michael, Yee, Jamil, Mayet, Robert D, Goldin, Mark R, Thursz, Pinelopi, Manousou
Publikováno v:
Alimentary Pharmacology & Therapeutics
Summary Background Atherosclerotic cardiovascular disease is a key cause of morbidity in non‐alcoholic fatty liver disease (NAFLD) but appropriate means to predict major acute cardiovascular events (MACE) are lacking. Aim To design a bespoke cardio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::84fed64a2588b65282479ba9ce5b0e6a
http://europepmc.org/articles/PMC6519040
http://europepmc.org/articles/PMC6519040
Autor:
Sven Pettersson, Monique Ryan, Nathan G. Lawler, Toby Richards, Edward Raby, Berin A. Boughton, Torben Kimhofer, Aude-Claire Morillon, Sze-How Bong, Dale W. Edgar, Rongchang Yang, Sofina Begum, Sung Tong Chin, Luke Whiley, Jerome D Coudert, Nicola Gray, Jeremy K. Nicholson, Elaine Holmes
Publikováno v:
Journal of Proteome Research
We performed quantitative metabolic phenotyping of blood plasma in parallel with cytokine/chemokine analysis from participants who were either SARS-CoV-2 (+) (n = 10) or SARS-CoV-2 (-) (n = 49). SARS-CoV-2 positivity was associated with a unique meta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33c0dd8c2cbc2564546160c7caa37523
http://hdl.handle.net/10044/1/91210
http://hdl.handle.net/10044/1/91210
Autor:
Wolfgang Bermel, Jeremy K. Nicholson, Philipp Nitschke, Reika Masuda, Toby Richards, John C. Lindon, Elaine Holmes, Hartmut Schaefer, Sze-How Bong, Sofina Begum, Samantha Lodge, Manfred Spraul, Tony Reinsperger, Julien Wist, Torben Kimhofer, Ruey Leng Loo
Publikováno v:
Analytical Chemistry
We have applied nuclear magnetic resonance spectroscopy based plasma phenotyping to reveal diagnostic molecular signatures of SARS-CoV-2 infection via combined diffusional and relaxation editing (DIRE). We compared plasma from healthy age-matched con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72bfd115c74be06ca808f29e261be295
Autor:
Elaine Holmes, Toby Richards, Jeremy K. Nicholson, Torben Kimhofer, Manfred Spraul, John C. Lindon, Hartmut Schaefer, Sofina Begum, Samantha Lodge, Philipp Nitschke, Sze-How Bong, Ruey Leng Loo
Publikováno v:
Journal of Proteome Research
The utility of low sample volume in vitro diagnostic (IVDr) proton nuclear magnetic resonance (1H NMR) spectroscopic experiments on blood plasma for information recovery from limited availability or high value samples was exemplified using plasma fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b586bf46cf0b5cb14ee762171dda725e