Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Torben, Knuschke"'
Autor:
Philine Steinbach, Eva Pastille, Lara Kaumanns, Alexandra Adamczyk, Kathrin Sutter, Wiebke Hansen, Ulf Dittmer, Jan Buer, Astrid M Westendorf, Torben Knuschke
Publikováno v:
PLoS Pathogens, Vol 20, Iss 1, p e1011982 (2024)
Influenza A virus (IAV) can cause severe respiratory infection leading to significant global morbidity and mortality through seasonal epidemics. Likewise, the constantly increasing number of cancer diseases is a growing problem. Nevertheless, the und
Externí odkaz:
https://doaj.org/article/a63e2a8e22f64398969f9161ce87c646
Autor:
Nataniel Białas, Viktoriya Sokolova, Selina Beatrice van derMeer, Torben Knuschke, Tatjana Ruks, Kai Klein, Astrid M. Westendorf, Matthias Epple
Publikováno v:
Nano Select, Vol 3, Iss 10, Pp 1407-1420 (2022)
Abstract The uptake of fluorescently labeled ultrasmall gold nanoparticles (2 nm) by Gram‐negative Escherichia coli bacteria occurs within 1–3 hours. This was demonstrated by confocal laser scanning microscopy (CLSM), structured illumination micr
Externí odkaz:
https://doaj.org/article/a4c50b3123e0494eb96e816a5a840515
Autor:
Christina Wenzek, Philine Steinbach, Florian Wirsdörfer, Kathrin Sutter, Julia D. Boehme, Robert Geffers, Robert Klopfleisch, Dunja Bruder, Verena Jendrossek, Jan Buer, Astrid M. Westendorf, Torben Knuschke
Publikováno v:
iScience, Vol 25, Iss 12, Pp 105540- (2022)
Summary: CD47 is an ubiquitously expressed surface molecule with significant impact on immune responses. However, its role for antiviral immunity is not fully understood. Here, we revealed that the expression of CD47 on immune cells seemed to disturb
Externí odkaz:
https://doaj.org/article/13de89e0b0ca48f9bd746945964e9b6d
Immunotherapy With Interferon α11, But Not Interferon Beta, Controls Persistent Retroviral Infection
Autor:
Mara Schwerdtfeger, Julia Dickow, Yasmin Schmitz, Sandra Francois, Zehra Karakoese, Anna Malyshkina, Torben Knuschke, Ulf Dittmer, Kathrin Sutter
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
Type I Interferons (IFNs), including numerous IFNα subtypes and IFNβ, are key molecules during innate and adaptive immune responses against viral infections. These cytokines exert various non-redundant biological activities, although binding to the
Externí odkaz:
https://doaj.org/article/6e632670a1494f1aa74e3e95bb636a60
Autor:
Torben Knuschke, Sebastian Kollenda, Christina Wenzek, Gennadiy Zelinskyy, Philine Steinbach, Ulf Dittmer, Jan Buer, Matthias Epple, Astrid M. Westendorf
Publikováno v:
mBio, Vol 12, Iss 1 (2021)
Despite significant efforts, vaccines are not yet available for every infectious pathogen, and the search for a protective approach to prevent the establishment of chronic infections, i.e., with HIV, continues. Immune checkpoint therapies targeting i
Externí odkaz:
https://doaj.org/article/c4b0311ffd9843a69b3db45c416f2a05
Autor:
Paul David, Malgorzata Drabczyk-Pluta, Eva Pastille, Torben Knuschke, Tanja Werner, Nadine Honke, Dominik A Megger, Ilseyar Akhmetzyanova, Namir Shaabani, Annette Eyking-Singer, Elke Cario, Olivia Kershaw, Achim D Gruber, Matthias Tenbusch, Kirsten K Dietze, Mirko Trilling, Jia Liu, Dirk Schadendorf, Hendrik Streeck, Karl S Lang, Youhua Xie, Lisa Zimmer, Barbara Sitek, Annette Paschen, Astrid M Westendorf, Ulf Dittmer, Gennadiy Zelinskyy
Publikováno v:
PLoS Pathogens, Vol 16, Iss 3, p e1008340 (2020)
Combination immunotherapy (CIT) is currently applied as a treatment for different cancers and is proposed as a cure strategy for chronic viral infections. Whether such therapies are efficient during an acute infection remains elusive. To address this
Externí odkaz:
https://doaj.org/article/9987cb67515b4dc9a412c66b03e91f68
Autor:
Florian Scheffel, Torben Knuschke, Lucas Otto, Sebastian Kollenda, Viktoriya Sokolova, Christine Cosmovici, Jan Buer, Jörg Timm, Matthias Epple, Astrid M. Westendorf
Publikováno v:
Vaccines, Vol 8, Iss 1, p 110 (2020)
The ability of vaccines to induce T cell responses is crucial for preventing diseases caused by viruses. Nanoparticles (NPs) are considered to be efficient tools for the initiation of potent immune responses. Calcium phosphate (CaP) NPs are a class o
Externí odkaz:
https://doaj.org/article/42cd973f5df14b3b91ea92f436fd25ae
Autor:
Torben Knuschke, Olga Rotan, Wibke Bayer, Sebastian Kollenda, Julia Dickow, Kathrin Sutter, Wiebke Hansen, Ulf Dittmer, Karl S. Lang, Matthias Epple, Jan Buer, Astrid M. Westendorf
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
T cell dysfunction and immunosuppression are characteristic for chronic viral infections and contribute to viral persistence. Overcoming these burdens is the goal of new therapeutic strategies to cure chronic infectious diseases. We recently describe
Externí odkaz:
https://doaj.org/article/d2061062d0c74c00851840501c37d264
Autor:
Katja Merches, Vishal Khairnar, Torben Knuschke, Namir Shaabani, Nadine Honke, Vikas Duhan, Mike Recher, Alexander A. Navarini, Cornelia Hardt, Dieter Häussinger, Burkhard Tümmler, Erich Gulbins, Anthony H. Futerman, Daniel Hoffmann, Florian Lang, Philipp A. Lang, Astrid M. Westendorf, Karl S. Lang
Publikováno v:
Cellular Physiology and Biochemistry, Vol 36, Iss 6, Pp 2379-2392 (2015)
Background: Type I interferon (IFN-I) predisposes to bacterial superinfections, an important problem during viral infection or treatment with interferon-alpha (IFN-α). IFN-I-induced neutropenia is one reason for the impaired bacterial control; howev
Externí odkaz:
https://doaj.org/article/d548a237db544f45966c2346f963b89c
Autor:
Matthias Epple, Viktoriya Sokolova, Mathis Kopp, Astrid M. Westendorf, Z Shi, Torben Knuschke, Jan Buer, Dongliang Yang, Annika Frede, Yanqin Du, Shunmei Huang
Publikováno v:
Biomedical Engineering / Biomedizinische Technik. 64:36-40
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fba7c2b7c6789f62c35b20af7d54b85
https://doi.org/10.1515/bmt-2019-7005
https://doi.org/10.1515/bmt-2019-7005