A method for detection of endogenous unmodified RNA in live bacterial cells

Autor: Toran, Paul T.

RNAs are dynamic molecules that orchestrate a breadth of processes for prokaryotes and eukaryotes in both the nucleus and cytoplasm. These processes include regulation of transcription, translation, and post-translational modifications. It has been d

Externí odkaz: https://hdl.handle.net/2144/15212

Sphingolipid metabolism determines the therapeutic efficacy of nanoliposomal ceramide in acute myeloid leukemia

Autor: Barth, Brian M., Wang, Weiyuan, Toran, Paul T., Fox, Todd E., Annageldiyev, Charyguly, Ondrasik, Regina M., Keasey, Nicole R., Brown, Timothy J., Devine, Viola G., Sullivan, Emily C., Cote, Andrea L., Papakotsi, Vasiliki, Tan, Su-Fern, Shanmugavelandy, Sriram S., Deering, Tye G., Needle, David B., Stern, Stephan T., Zhu, Junjia, Liao, Jason, Viny, Aaron D., Feith, David J., Levine, Ross L., Wang, Hong-Gang, Loughran, Thomas P., Jr, Sharma, Arati, Kester, Mark ^*, Claxton, David F.

Publikováno v: In Blood Advances 10 September 2019 3(17):2598-2603

Combinatorial Efficacy of Quercitin and Nanoliposomal Ceramide for Acute Myeloid Leukemia

Autor: McGill, Colin M., Brown, Timothy J., Fisher, Lindsey N., Gustafson, Sally J., Dunlap, Kriya L., Beck, Adam J., Toran, Paul T., Claxton, David F., Barth, Brian M.

Acute myeloid leukemia (AML) is an aggressive hematological malignancy with limited treatment options. Inflammation is often a contributing factor to the development and progression of AML, and related diseases, and can potentiate therapy failure. Pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b9ae900108614e13990b8e1e8b2fd316
https://europepmc.org/articles/PMC6349237/

Obesity Promotes the Ceramide-Mediated NADPH Oxidase in Acute Myeloid Leukemia.

Autor: Wang W; Department of Molecular, Cellular, and Biomedical Sciences, University of New Hampshire, Durham, NH 03824 USA.; Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta GA 30322 USA., Sabol RJ; Department of Molecular, Cellular, and Biomedical Sciences, University of New Hampshire, Durham, NH 03824 USA., Day AM; Department of Molecular, Cellular, and Biomedical Sciences, University of New Hampshire, Durham, NH 03824 USA., Hathorn TG; Department of Molecular, Cellular, and Biomedical Sciences, University of New Hampshire, Durham, NH 03824 USA., Clark MN; Department of Molecular, Cellular, and Biomedical Sciences, University of New Hampshire, Durham, NH 03824 USA., Connell SE; Department of Molecular, Cellular, and Biomedical Sciences, University of New Hampshire, Durham, NH 03824 USA., Mantis EA; Department of Molecular, Cellular, and Biomedical Sciences, University of New Hampshire, Durham, NH 03824 USA., Traore M; Department of Molecular, Cellular, and Biomedical Sciences, University of New Hampshire, Durham, NH 03824 USA., Siciliano JM; Department of Molecular, Cellular, and Biomedical Sciences, University of New Hampshire, Durham, NH 03824 USA., Arsenault EJ; Department of Molecular, Cellular, and Biomedical Sciences, University of New Hampshire, Durham, NH 03824 USA., Labrecque NT; Department of Molecular, Cellular, and Biomedical Sciences, University of New Hampshire, Durham, NH 03824 USA., Sullivan EC; Department of Molecular, Cellular, and Biomedical Sciences, University of New Hampshire, Durham, NH 03824 USA., Cote AL; Department of Molecular, Cellular, and Biomedical Sciences, University of New Hampshire, Durham, NH 03824 USA.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139 USA.; The Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard University, Cambridge, MA 02139 USA., Toran PT; Department of Molecular, Cellular, and Biomedical Sciences, University of New Hampshire, Durham, NH 03824 USA., Barth BM; Department of Molecular, Cellular, and Biomedical Sciences, University of New Hampshire, Durham, NH 03824 USA.; Department of Natural Sciences, University of Alaska Southeast, Juneau, AK 99801 USA.

Publikováno v: Journal of blood disorders and malignancies [J Blood Disord Malig] 2024; Vol. 2 (1). Date of Electronic Publication: 2024 Apr 15.

Combinatorial Efficacy of Quercitin and Nanoliposomal Ceramide for Acute Myeloid Leukemia.

Autor: McGill CM; Department of Chemistry, University of Alaska-Anchorage, Anchorage, AK 99508 USA., Brown TJ; Department of Medicine, Division of Hematology and Oncology, Penn State Hershey Cancer Institute, Penn State College of Medicine, Hershey, PA 17033 USA.; Department of Internal Medicine, The University of Texas Southwestern Medical Center, Dallas, TX 75390 USA., Fisher LN; Department of Medicine, Division of Hematology and Oncology, Penn State Hershey Cancer Institute, Penn State College of Medicine, Hershey, PA 17033 USA., Gustafson SJ; Department of Chemistry and Biochemistry, University of Alaska-Fairbanks, Fairbanks, AK 99775., Dunlap KL; Department of Chemistry and Biochemistry, University of Alaska-Fairbanks, Fairbanks, AK 99775., Beck AJ; Drug Discovery, Development, and Delivery Core, Penn State College of Medicine, Hershey, PA 17033 USA., Toran PT; Department of Molecular, Cellular and Biomedical Sciences, University of New Hampshire, Durham, NH 03824 USA., Claxton DF; Department of Medicine, Division of Hematology and Oncology, Penn State Hershey Cancer Institute, Penn State College of Medicine, Hershey, PA 17033 USA., Barth BM; Department of Medicine, Division of Hematology and Oncology, Penn State Hershey Cancer Institute, Penn State College of Medicine, Hershey, PA 17033 USA.; Department of Molecular, Cellular and Biomedical Sciences, University of New Hampshire, Durham, NH 03824 USA.

Publikováno v: International journal of biopharmaceutical sciences [Int J Biopharm Sci] 2018; Vol. 1 (1). Date of Electronic Publication: 2018 Jan 31.