Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Torahiko Kishikawa"'
Publikováno v:
Chemical and Pharmaceutical Bulletin. 26:3124-3134
The metabolism of 4-ethoxy-2-methyl-5-morpholino-3 (2H)-pyridazinone (M73101) in rabbits and the pharmacological activities of metabolites were investigated. Rabbits orally received the drug in a dose of 100 mg/kg excreted ten metabolites together wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24c5eec54b55f6d0749c32720f46eb24
https://doi.org/10.1248/cpb.26.3124
https://doi.org/10.1248/cpb.26.3124
Autor:
Hidetaka Yuki, Torahiko Kishikawa
Publikováno v:
Chemical and Pharmaceutical Bulletin. 14:1365-1370
1-Phenyl-5, 6-diaminouracil (IX) or-2-thiouracil (X) prepared from 1-phenyl-6-aminouracil (V) or 1-phenyl-6-amino-2-thiouracil (VI) in an usual way was fused with urea or thiourea to yield 3-phenyluric acid and 3-phenylthiouric acid derivatives (XII,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6683e396c60ed580cd76c223fa31e25
https://doi.org/10.1248/cpb.14.1365
https://doi.org/10.1248/cpb.14.1365
Autor:
Torahiko Kishikawa
Publikováno v:
Chemical and Pharmaceutical Bulletin. 17:2494-2501
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7b993a51b84a5e09d4b5e82d30e6d71
https://doi.org/10.1248/cpb.17.2494
https://doi.org/10.1248/cpb.17.2494
Autor:
Torahiko Kishikawa, Hidetaka Yuki
Publikováno v:
Chemical and Pharmaceutical Bulletin. 14:1360-1364
Condensation of 4-ethylthio-5-nitro-6-chloropyrimidine with methyl 1-amino-1-deoxy-2, 3, 4-tri-O-acetyl-β-D-glucopyranuronate was effectd to give methyl 1-deoxy-1-(4-ethylthio-5-nitro-6-pyrimidinylamino)-2, 3-4-tri-O-acetyl-D-glucopyranuronate (VI).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::741a5d0220d48337c8a9fd79a31faa3e
https://doi.org/10.1248/cpb.14.1360
https://doi.org/10.1248/cpb.14.1360
Publikováno v:
Chemical and Pharmaceutical Bulletin. 15:1052-1055
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6419956ea916043ce90bef947156a9b4
https://doi.org/10.1248/cpb.15.1052
https://doi.org/10.1248/cpb.15.1052
Publikováno v:
Chemical and Pharmaceutical Bulletin. 17:699-702
Condensation of methyl (tri-O-acetyl-a-D-glucopyranosyl bromide) uronate with silver 2-pyridyl oxide in toluene gave methyl (2-pyridyl 2, 3, 4-tri-O-acetyl-β-D-glucopyranosid)-uronate (III). Removal of the protecting groups from III afforded the O-g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f6f81e71aa5d294afbcca2134ace406
https://doi.org/10.1248/cpb.17.699
https://doi.org/10.1248/cpb.17.699
Publikováno v:
Chemicalpharmaceutical bulletin. 27(2)
The species differences of metabolism of 4-ethoxy-2-methyl-5-morpholino-3 (2H)-pyridazinone (M73101) were studied. The urinary and fecal metabolites in six animals (dog, mouse, rabbit, rat, monkey, and guinea pig) were analyzed qualitatively and quan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72b1b47d282c92e3db18c25796deb7fd
https://pubmed.ncbi.nlm.nih.gov/109218
https://pubmed.ncbi.nlm.nih.gov/109218
Publikováno v:
Chemicalpharmaceutical bulletin. 14(12)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58d55192d54244d8fbbfbb9119f2e16b
https://pubmed.ncbi.nlm.nih.gov/5977955
https://pubmed.ncbi.nlm.nih.gov/5977955
Autor:
Shigeru Hayakawa, Seikichi Suzuki, Yasuo Tohira, Hidetaka Yuki, Torahiko Kishikawa, Fumihiko Sano
Publikováno v:
Chemicalpharmaceutical bulletin. 15(8)
N-chloro compounds were synthesized and their virus inactivating activity and probable mechanism of the action were investigated. It is likely that the N-chloro compounds oxidize the sulfhydryl groups of the viral protein coat to form disulfide, disu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85a24d1d88588a0c29a8d529f9cacc55
https://pubmed.ncbi.nlm.nih.gov/5583167
https://pubmed.ncbi.nlm.nih.gov/5583167